| Definition | Rickettsia africae ESF-5 chromosome, complete genome. |
|---|---|
| Accession | NC_012633 |
| Length | 1,278,540 |
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The map label for this gene is fabG [H]
Identifier: 229587123
GI number: 229587123
Start: 1094384
End: 1095109
Strand: Direct
Name: fabG [H]
Synonym: RAF_ORF1078
Alternate gene names: 229587123
Gene position: 1094384-1095109 (Clockwise)
Preceding gene: 229587122
Following gene: 229587124
Centisome position: 85.6
GC content: 34.85
Gene sequence:
>726_bases ATGATTGATTTAACAGGTAAAACTTCCTTAATTACGGGAGCTTCAGGAGGCATAGGCGGAGCTATAGCGAGGTTACTACA CAAACTCGGAAGCCATGTAATTATTAGCGGTAGTAATGAGGAAAAATTAAAATCCCTTGGAAAGGTTGTAAAAGATAATT ATACGATAGAAGTATGTAATCTTGCCGATAAGGAAGAATGTAGCAATTTAATATCTAAAGCATCAAAGTTAGATATTTTA GTATGTAATGCCGGTATTACTAGCGATACGCTAGCAATTAGAATGAAAGATGAAGATTTTGACAAAGTTATTGATATTAA TTTAAAAGCAAATTTTATTTTAAATCGTGAAGCAATAAAAAAAATGATACAAAACAGGTATGGACGTATTATTAACATAT CTTCAATAGTAGGAATTTCAGGTAACCCCGGGCAGGCTAATTATTGTGCTTCTAAAGCAGGTTTAATAGGTATGACCAAA TCGCTCGCTTACGAAGTTGCAACCAGAGGCATTACGGTTAACACAGTAGCTCCAGGATTTATTAAATCAGATATGACCGA TAAACTAAATGAAAAACAAAGAGAAGCTATAATACAAAAAATTCCGCTAGGCACTTACGGTATGCCGGAAGACGTGGCAA ACGCAGTTGCATTTTTAGCAAGCGATCAGGCATCATATATTACCGGTCAAACTATACATGTAAACGGTGGTATGTTAATG GTATAA
Upstream 100 bases:
>100_bases TTAAAAGAACATCCACAAATTTCCAACGAAATTGAGAAAATAATACGTGAAAAATCGTCAAAAATTACTAATATAAATCT TGATCAAACGGAGGAAGAAA
Downstream 100 bases:
>100_bases AAATTAATAAGATTATTTTGTGCTAGCATAAAATAATTTTTTGTGCTAGAAGTTCTTTTAAAGATAAAATGTAATGAATA TTTTAAATAAATATTCATAC
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 241; Mature: 241
Protein sequence:
>241_residues MIDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGKVVKDNYTIEVCNLADKEECSNLISKASKLDIL VCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIKKMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLAYEVATRGITVNTVAPGFIKSDMTDKLNEKQREAIIQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V
Sequences:
>Translated_241_residues MIDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGKVVKDNYTIEVCNLADKEECSNLISKASKLDIL VCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIKKMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLAYEVATRGITVNTVAPGFIKSDMTDKLNEKQREAIIQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V >Mature_241_residues MIDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGKVVKDNYTIEVCNLADKEECSNLISKASKLDIL VCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIKKMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLAYEVATRGITVNTVAPGFIKSDMTDKLNEKQREAIIQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=38.7096774193548, Blast_Score=165, Evalue=3e-41, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=37.2384937238494, Blast_Score=153, Evalue=1e-37, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=36.0655737704918, Blast_Score=147, Evalue=8e-36, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=34.2629482071713, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=33.0612244897959, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.4516129032258, Blast_Score=118, Evalue=5e-27, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=30.7053941908714, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI4504505, Length=255, Percent_Identity=31.3725490196078, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=32.6424870466321, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI66933014, Length=242, Percent_Identity=27.6859504132231, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=29.296875, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=32.9608938547486, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=31.1224489795918, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI226371731, Length=211, Percent_Identity=28.436018957346, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI59889578, Length=220, Percent_Identity=28.6363636363636, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=27.9187817258883, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=27.2, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI4503301, Length=247, Percent_Identity=28.7449392712551, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.126213592233, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI142976729, Length=230, Percent_Identity=29.5652173913043, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=26.953125, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI157739938, Length=226, Percent_Identity=28.7610619469027, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI109715829, Length=233, Percent_Identity=28.3261802575107, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=25.1282051282051, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI224922801, Length=182, Percent_Identity=29.1208791208791, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI225579078, Length=205, Percent_Identity=26.3414634146341, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI50726952, Length=205, Percent_Identity=28.2926829268293, Blast_Score=66, Evalue=2e-11, Organism=Homo sapiens, GI44680136, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI44680133, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI17738292, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI302344755, Length=101, Percent_Identity=34.6534653465347, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI25282469, Length=218, Percent_Identity=23.394495412844, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=49.1803278688525, Blast_Score=235, Evalue=2e-63, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=34.9397590361446, Blast_Score=138, Evalue=3e-34, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=33.7349397590361, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=32.258064516129, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=35.5932203389831, Blast_Score=124, Evalue=7e-30, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.9156626506024, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=31.6, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=30.8641975308642, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=32.3770491803279, Blast_Score=107, Evalue=5e-25, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=30.6122448979592, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1789057, Length=179, Percent_Identity=35.7541899441341, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.9236947791165, Blast_Score=95, Evalue=3e-21, Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=30.0448430493274, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1787526, Length=239, Percent_Identity=26.3598326359833, Blast_Score=74, Evalue=6e-15, Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=25.8706467661692, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=38.5245901639344, Blast_Score=160, Evalue=5e-40, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=35.3909465020576, Blast_Score=147, Evalue=3e-36, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=34.2857142857143, Blast_Score=142, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=33.7349397590361, Blast_Score=120, Evalue=5e-28, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.9588014981273, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=33.587786259542, Blast_Score=113, Evalue=7e-26, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=32.1969696969697, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=33.0827067669173, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=31.8352059925094, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=33.469387755102, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=32.5842696629214, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=32.089552238806, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=31.3432835820896, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=31.0204081632653, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=31.3008130081301, Blast_Score=105, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.9473684210526, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.2238805970149, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=32.6996197718631, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.7116104868914, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=30.9433962264151, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=30.0411522633745, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=32.9896907216495, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=33.2, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=29.8039215686275, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=29.3877551020408, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=33.4661354581673, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=31.2, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538486, Length=271, Percent_Identity=29.8892988929889, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=31.8681318681319, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=27.4725274725275, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=29.6, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17508895, Length=246, Percent_Identity=26.0162601626016, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=31.25, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI193207185, Length=149, Percent_Identity=33.5570469798658, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=32.6732673267327, Blast_Score=103, Evalue=2e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=28.6852589641434, Blast_Score=92, Evalue=6e-20, Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=29.3172690763052, Blast_Score=76, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=37.037037037037, Blast_Score=158, Evalue=3e-39, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=37.0967741935484, Blast_Score=147, Evalue=7e-36, Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=32.6530612244898, Blast_Score=125, Evalue=3e-29, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=34.8, Blast_Score=120, Evalue=6e-28, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=31.7991631799163, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=30.46875, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=32.6693227091633, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI18859837, Length=244, Percent_Identity=32.3770491803279, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=29.4416243654822, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=29.4416243654822, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24649181, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI28574402, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24584752, Length=199, Percent_Identity=28.1407035175879, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24640492, Length=225, Percent_Identity=26.2222222222222, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=26.8571428571429, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI221510726, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364892, Length=177, Percent_Identity=29.9435028248588, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25736; Mature: 25736
Theoretical pI: Translated: 8.59; Mature: 8.59
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGKVVKDNYTIEVCN CEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEC LADKEECSNLISKASKLDILVCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIK CCCHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEEECHHHHH KMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLAYEVATRGITVNTVAPGF HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCH IKSDMTDKLNEKQREAIIQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEECCCEEE V C >Mature Secondary Structure MIDLTGKTSLITGASGGIGGAIARLLHKLGSHVIISGSNEEKLKSLGKVVKDNYTIEVCN CEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEC LADKEECSNLISKASKLDILVCNAGITSDTLAIRMKDEDFDKVIDINLKANFILNREAIK CCCHHHHHHHHHHHHHCEEEEECCCCCCCEEEEEECCCCCCEEEEEEEEEEEEECHHHHH KMIQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLAYEVATRGITVNTVAPGF HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEECCCCCH IKSDMTDKLNEKQREAIIQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEECCCEEE V C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]