Click here to switch to the map view.

The map label for this gene is engA

Identifier: 229587033

GI number: 229587033

Start: 966136

End: 967479

Strand: Direct

Name: engA

Synonym: RAF_ORF0936

Alternate gene names: 229587033

Gene position: 966136-967479 (Clockwise)

Preceding gene: 229587032

Following gene: 229587037

Centisome position: 75.57

GC content: 33.78

Gene sequence:

>1344_bases
ATGACTAAGCAAATCATTACTTTAGTTGGCCGTCCGAATGTAGGCAAATCAACGCTTTTCAATAGATTAAGCATACGTAA
AAAAGCTATCGTTCACGATTTGCCAGGCGTCACTAGAGATAGAAAATATACAGACGGCAAAATCGGCTCTTTTGAATTTT
TGTTAATTGATACCCCAGGACTTGACGAGCATCCTAATAGTATGGGAGAGAGGTTAATTGAGCAGACTACTAAAGCAATT
TTAGAGGCAGATTTAATTTGCTTTATGGTTGACGGTAGAAGCGGAATATTACCTGATGATAAGCTACTTAGTAGTTTTGT
TAGAAAATATAATAAGCCTGCTATATTGGTAGTTAATAAATGCGAGAAAGCTTTTGATTTTGATAAAGAGTACTACAAAT
TAGGGTTTGATAGTATGATAGCTATCTCTGCCGAACATGGCACAGGCTTAATTGATTTATATGACGAAATTATTGCCAAG
TTACCTGAAGAAGAATCAATCAAGACAAATATAGCCGATCCAATTAAAGGAGATTGTTTGCAAATAGTAGTTAGTGGCAG
ACCTAACGCCGGAAAATCTACTTTTATAAACGCTCTTATTAATGATGAAAGATTATTAACCGGTCCTGAAGCCGGCATTA
CTCGTGAATCAATTGAAATTGATTGGCAATATAAAAATAATCATATTAAATTGATTGATACAGCAGGACTCCGCAAGAAA
TCTACTATTACAAAGTCTTTAGAAAAATTATCGGCATCGGATACTATTAACAGTATTAAATTTGCTAATACCGTAATCTT
AATGATTGATGCTTTAGCTCCTTTAAAACAACAAGATTTAAATATTGCAAGCCATGTGGTAAATGAAGGAAGAAGTATAG
TTATAGTAGTGAATAAATGGGATTTAGTTAAAGAATCCGAAAAAGAAGCATTTCAGGAAGAATTTTATTATCAGATAAAT
ACTCATCTGCCTCAAGTTAAAGGTATCCCCGTTCTATTCATTTCAGCAATAAATAAACAAAATATTGAACAAGTGCTAGA
TGCTTGTCTTAAAATTTATAAAATTTGGAATAAGAAAATAACTACTAGCAAATTAAATGAATGGCTTAATTTTACTACGG
AAGCACATCTGCTGCCTTTACAAAAAGGAGGCAGAAGAGTGCGTGTAAAGTATATGACTCAAACAAAAACCCGCCCCCCT
ACTTTCAAACTATTCTCCAATAATCCGGAAAAAATTACCGATAGCTATACTAGGTATTTAGTAAACAATATGCGTGAGGC
TTTTGACATGCCGGGCGTTCCTATTAGATTCATTTACGTAAAAACTAAAAACCCGTATGTGTAG

Upstream 100 bases:

>100_bases
ATACGGCATATTAATAAAAAATACACCTATTATAATAGCAAATATAGTAGGTTTTATCGGGGCATTATTAGTTCTCTTAA
CCATAATAATATATTAAATA

Downstream 100 bases:

>100_bases
TTTAAAATTAATTAATAACAGTTTAGTTATTAGCACCGAAAAATCTGAATTAGATATATTACTAGATAATATTACTGATT
CTAATTGTCATCATAAATTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGERLIEQTTKAI
LEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAK
LPEEESIKTNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKK
STITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQIN
THLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPP
TFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFIYVKTKNPYV

Sequences:

>Translated_447_residues
MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGERLIEQTTKAI
LEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAK
LPEEESIKTNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKK
STITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQIN
THLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPP
TFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFIYVKTKNPYV
>Mature_446_residues
TKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGERLIEQTTKAIL
EADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKL
PEEESIKTNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKS
TITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINT
HLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPT
FKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFIYVKTKNPYV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=36.1111111111111, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788919, Length=168, Percent_Identity=35.1190476190476, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367268, Length=87, Percent_Identity=41.3793103448276, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=125, Percent_Identity=36, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_RICAE (C3PPD1)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845534.1
- GeneID:   7814935
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0936
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50743; Mature: 50612

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
LDEHPNSMGERLIEQTTKAILEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
CEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIKTNIADPIKGDCL
CHHHHCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
QIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKK
EEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEECEEEEEEEEECCEEEEEECCCCCHH
STITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKW
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHHCCHHHHHHHHCCCEEEEEEECC
DLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKI
CHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHCCCC
TTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYL
CHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
VNNMREAFDMPGVPIRFIYVKTKNPYV
HHHHHHHHCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
TKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCC
LDEHPNSMGERLIEQTTKAILEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEC
CEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIKTNIADPIKGDCL
CHHHHCCCHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
QIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKK
EEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCEECEEEEEEEEECCEEEEEECCCCCHH
STITKSLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKW
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHHCCHHHHHHHHCCCEEEEEEECC
DLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKI
CHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHHHCCCC
TTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYL
CHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHH
VNNMREAFDMPGVPIRFIYVKTKNPYV
HHHHHHHHCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA