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The map label for this gene is dnaA

Identifier: 229586943

GI number: 229586943

Start: 871344

End: 872735

Strand: Direct

Name: dnaA

Synonym: RAF_ORF0831

Alternate gene names: 229586943

Gene position: 871344-872735 (Clockwise)

Preceding gene: 229586942

Following gene: 229586945

Centisome position: 68.15

GC content: 34.77

Gene sequence:

>1392_bases
GTGAGTACTAACCAAATAATTTTAACGGATCAAGGTAATAATTATGTAAATGTCTGGAGTCACGTGGCTCAAGATCTTTA
CAATCATTACGGTGAAACTCTATATAATAGCTGGTTTAGTAAAGTCAATTTTATAGAGTCTTCATTAAATACCGTTATTC
TTTGTGCCCCTACTAACTTTGTTAGAGATTGGATAAAATCCAAGTACTCTATGGTTATATTGCAACTATTTCAACATTAT
AATAATACCATTAAGTCAATTGAAATAATTACTAAAGAGTTACCTGGAACAACCCAAACAGTTACAGAATTACCTACTAA
GACTTTTGCCGATATCGGCAGCAGTGAGCTTAATTCGGAAAATATCTTTTCAACCCTTGATGTACGTTTTACTTTCGATA
ATTTTGTGGTTGGAGCCCCAAATGAGCTAGCTTATGCAGCCGCAAGAGCGGTTGCAGAATCATCAGGTGCGGTTTCTGAG
TCTAATCCGCTTTTTCTATATGGCGGCGTAGGGCTTGGTAAAACTCATTTAATGCATGCAATCGGTTGGTACATCAAGCA
GCATAATCCAAGCCGCAAAGTGATATACATGTCGGCAGAAAAATTTATGTATCAATTTGTTAAAGCTCTGCGTAACAAAG
AAGTAATCTCGTTTAAAGAGAAATTTCGTTCGGTTGACGTGTTAATGATTGATGATATTCAATTTATTTGTGGTAAAGAT
AGTACGCAGGAAGAATTTTTCCATACTTTTAATACATTGATTGATAATAACCGTCAAATGGTTATTTCTTGTGATAGATC
GCCTTCAGATTTAGATAATATTGAAGATCGGATAAAATCTCGTCTTGGATGGGGCTTAGTTGCCGACGTTCATAGTACTA
CTTATGAGCTACGACTCGGTATTCTAGAATCTAAGATTGAGCAGATGAACGTTAAAATACCAAAAGACGTAATTGATTTT
TTAGCATCTAAAATCGTTTCAAACGTTAGAGAACTTGAAGGAGCTTTAAATAAGGTGATCGCTCATTCTAATTTTACTTT
AAAAGAAATTACACTCGAAAACACACAAAATATTTTGCGGGATTTACTGCGTTCTAATGAAAGAATAATTACCGTTGAAG
ATATTCAGAAAAAGGTAGCTAGCCGTTATAATATTAAGTTATCCGATATGTCTTCATCAAGGAGATTACGAGAAGTTGCA
AGACCGCGTCAAATAGCCATGTATCTTAGTAAAGCATTAACGCCGAAAAGTCTTGCAGATATCGGTAAAAAATTCGGTAA
AAAAGACCACACGACGGTTATGCATGCTATTAAGAAAGTAGAAGAATTACTGGAAAACGATATAGAATTACGCGAAGAGA
TTCATTTGCTAATGAAAATATTGCAGAACTAA

Upstream 100 bases:

>100_bases
TAATATAGGTTATAAAAATTGTTATAATATTAGTGACGGCTTTGAAGGAAATAATCAAGATAAAGGCTGGAAACAAAATA
ACTTACCGTGGCAGTTTTAA

Downstream 100 bases:

>100_bases
ATGTCATACCGTAGTCAAGCTGACTTTGTTGCATGGTCCGAAAAACCGATTCGATGTCATTCCCGCAAAATCGGGAATCC
CGGGTAAAGCAAAATAAATC

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSTNQIILTDQGNNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHY
NNTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSE
SNPLFLYGGVGLGKTHLMHAIGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKD
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDF
LASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVA
RPRQIAMYLSKALTPKSLADIGKKFGKKDHTTVMHAIKKVEELLENDIELREEIHLLMKILQN

Sequences:

>Translated_463_residues
MSTNQIILTDQGNNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHY
NNTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSE
SNPLFLYGGVGLGKTHLMHAIGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKD
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDF
LASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVA
RPRQIAMYLSKALTPKSLADIGKKFGKKDHTTVMHAIKKVEELLENDIELREEIHLLMKILQN
>Mature_462_residues
STNQIILTDQGNNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHYN
NTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSES
NPLFLYGGVGLGKTHLMHAIGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKDS
TQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDFL
ASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVAR
PRQIAMYLSKALTPKSLADIGKKFGKKDHTTVMHAIKKVEELLENDIELREEIHLLMKILQN

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=466, Percent_Identity=41.8454935622318, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI226510964, Length=232, Percent_Identity=23.7068965517241, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_RICAE (C3PP41)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002845444.1
- GeneID:   7815637
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0831
- OMA:   CHTLNAL
- ProtClustDB:   PRK00149
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 52965; Mature: 52834

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQIILTDQGNNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNF
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
VRDWIKSKYSMVILQLFQHYNNTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCCC
NIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSESNPLFLYGGVGLGKTHLMHA
CCCEEEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHH
IGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKD
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCHHCCCCC
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ILESKIEQMNVKIPKDVIDFLASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
DLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVARPRQIAMYLSKALTPKSLAD
HHHHCCCCEEEHHHHHHHHHHHCCEEEECCCHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
IGKKFGKKDHTTVMHAIKKVEELLENDIELREEIHLLMKILQN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STNQIILTDQGNNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNF
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
VRDWIKSKYSMVILQLFQHYNNTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCCC
NIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSESNPLFLYGGVGLGKTHLMHA
CCCEEEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHH
IGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKD
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCHHCCCCC
STQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLG
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHH
ILESKIEQMNVKIPKDVIDFLASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHH
DLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVARPRQIAMYLSKALTPKSLAD
HHHHCCCCEEEHHHHHHHHHHHCCEEEECCCHHHHHHHHHCHHHHHHHHHHCCCHHHHHH
IGKKFGKKDHTTVMHAIKKVEELLENDIELREEIHLLMKILQN
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA