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The map label for this gene is spoT3 [H]

Identifier: 229586921

GI number: 229586921

Start: 845228

End: 845497

Strand: Direct

Name: spoT3 [H]

Synonym: RAF_ORF0805

Alternate gene names: 229586921

Gene position: 845228-845497 (Clockwise)

Preceding gene: 229586919

Following gene: 229586923

Centisome position: 66.11

GC content: 35.56

Gene sequence:

>270_bases
ATGCGTCAATCAGACAATCCTTATTATTCGCACCCGATTGAGGTAAAAATTATGCTTGCTGAATTTGTAGCTGAAGAAGC
ACCTAAGCTTTATAACATTATTATGCTGCAAGCCGCTTTACTTCATGATACTATTGAAGACACTGAATTAACTGAAGAAG
CAATTACCGAAATTTTTGGACCGGAAGTAGCAAAACACGTAGAAGGTCTAACTAGAATTAAATCTTACGGGAAGATAAGT
AGCGGAGAAAGCCTAATACTTATTAATTAA

Upstream 100 bases:

>100_bases
TACTTGATAAACTCGAATATTTAAATACTAAAGTAGCAAATCCTATAGATATACTCGAAATCACAAAAGGTATCTACTAT
GCACGTAACACGGTTCTCAA

Downstream 100 bases:

>100_bases
AGAGAAAAGAGACAATACGGCATTAATAAAATTATTTGACCGAATTCATAATGTGCAAACTTTGGGAGTTAAATCACCTG
AGAAAGCTAGAAAAATTATT

Product: Guanosine polyphosphate pyrophosphohydrolase/synthetase

Products: NA

Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase [H]

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MRQSDNPYYSHPIEVKIMLAEFVAEEAPKLYNIIMLQAALLHDTIEDTELTEEAITEIFGPEVAKHVEGLTRIKSYGKIS
SGESLILIN

Sequences:

>Translated_89_residues
MRQSDNPYYSHPIEVKIMLAEFVAEEAPKLYNIIMLQAALLHDTIEDTELTEEAITEIFGPEVAKHVEGLTRIKSYGKIS
SGESLILIN
>Mature_89_residues
MRQSDNPYYSHPIEVKIMLAEFVAEEAPKLYNIIMLQAALLHDTIEDTELTEEAITEIFGPEVAKHVEGLTRIKSYGKIS
SGESLILIN

Specific function: Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Plays a role in ada

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =2.7.6.5 [H]

Molecular weight: Translated: 10019; Mature: 10019

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSDNPYYSHPIEVKIMLAEFVAEEAPKLYNIIMLQAALLHDTIEDTELTEEAITEIFG
CCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PEVAKHVEGLTRIKSYGKISSGESLILIN
HHHHHHHHHHHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MRQSDNPYYSHPIEVKIMLAEFVAEEAPKLYNIIMLQAALLHDTIEDTELTEEAITEIFG
CCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PEVAKHVEGLTRIKSYGKISSGESLILIN
HHHHHHHHHHHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA