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The map label for this gene is 229586723

Identifier: 229586723

GI number: 229586723

Start: 597764

End: 599446

Strand: Direct

Name: 229586723

Synonym: RAF_ORF0572

Alternate gene names: NA

Gene position: 597764-599446 (Clockwise)

Preceding gene: 229586721

Following gene: 229586724

Centisome position: 46.75

GC content: 36.48

Gene sequence:

>1683_bases
ATGTCATCATTCAACATCAAAAATCATAAAAATGATCTGCTATTTGTACCGCTAGGGGGATCTAATGAAATAGGTATGAA
TCTTAATCTTTACCATTATCAAGGTCAATGGTTAATGATTGATTGTGGTAGCGGTTTTGCCGATGATTATTTACCCGGTG
TTGATATGATAATTGCTGATAGCAGCTTTATCGAGAAATATAAAAAAGATATAGTAGGTCTGATTTTAACTCATGCTCAC
GAGGATCATTTAGGTGGAGTCCAATATTTATGGCATAGACTTAAATGTCCTATTTATATTACTACTTTTACAGCAAATTT
TCTAAAAATTCGTTTAAATGAATATGATTTTGCTAAAAATATAAAAATTCATGAAGTAAAACCCGGTAGTAAAATAAATC
TAGATCCTTTTTCCTTAGAGATGGTGCCACTGACTCACTCGGCTCCTGAAATGCAAGCAATTATGATCCGTACGGATGCA
GGTAATATTTTACATACGGGGGATTGGAAATTTGATAACGATCCGATACTTGGGAAAAAAGCCGATGAGGAGCTTTTAAA
ATCTTACGGAGATGAAGGGGTTCTTGCACTTGTTTGTGATTCAACTAACGTATTTAATAAAGGAAGCTCAGGTTCTGAGG
GGGATGTTAGAAAAAGTTTAGTAGATATTATAGCCGGTTGTCCTCAAATGGTAGTAGTTTCAACCTTTGCCTCTAATTTA
GCACGGCTTGATACAATAATTCATGCTGCAGGGCTTGCGGGTAGAAAAGTAGTCTTAACCGGTAGAAGTTTGCACCGTAT
GATGCTTGCTGCGCAGGAAAGCGGCTATTTGAAAGATATTGCTCCTCTAATTAGTGAACGTGATGTTAGCAGATTTAGAA
GAGAAGAATTATTAGTAATTGCTACCGGTTGTCAAGGTGAGCCTATGGCTGCTACCGCAAAACTGGCTAGTAATTCTCAT
CCGTCTATAAAGCTTGTTCCTAAGGATACAATGATTTTTTCTTCAAAAATTATTCCGGGTAATGAAAAGAAAATATTCAG
GCTATTTAATATATTTGTTAAAGCCGGTGTAGAAGTTATTACTGAGCGAGACCATTTTGTACATGTTTCAGGACATCCAT
CGATTGACGAGCTACAAAAAATGTATTCTCTAATTAGACCGAATATTTGTATACCTGTTCACGGCGAGCCTGTACATATT
CATGAACATGTTAAGCTTGCTAAGAAAAACGGCATAAAACAGGTAGTAGAGGTTGAAAATGGTAGTGTAGTACTGCTTGA
ACCTAATAATGCAAAAGTAATTTCAAAGGTTGAAAACGGTTATTTAGCTGTTGACGGTAATTATTTGCTGCCCGTTGAAT
CTCCGATTTTCAAAGCTAGAAGACGTATGCGTGAGTCGGGTATCGTGGTAGCATCAGTAGTCATTAATAAAAAAGGACTA
CTTGCTGCAAACCCAATGCTGTCTATGCCCGGGCTGCTTGATCCGAAAGAGGATATGGCATTAGTTAACCTCATTAAAAA
CGACATTAAAGAACTTGTTACCATTCAAAATAAACAGGCTAAAAAAGCATTGTCGGATGAACAAGTAATCGAGGCAATAA
AAGGAACAATCCGTAAAACCTTAAAACAAGAAATTAATAAGTCACCCGTTATAATAGTAAATCTTGAGAAAGCTGTGGAG
TAG

Upstream 100 bases:

>100_bases
ATTTTATTTATATTCATTATATGAATTTCTTTTTTAATATATAGACGCTTAACTAATAATAAGTTATAAGAATAAAATAA
AATAAATATTAAGTTAAATT

Downstream 100 bases:

>100_bases
TGAAATTGTTATTGTAAGTAGGTATTGTTTTATGGCTCGAGAAATTCGTTCAATGTCATTCCCGCCTTCGTGAGAATGAC
ATAAACAAGCCAAGCAACGA

Product: Putative hydrolase of the metallo-beta-lactamase superfamily

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSSFNIKNHKNDLLFVPLGGSNEIGMNLNLYHYQGQWLMIDCGSGFADDYLPGVDMIIADSSFIEKYKKDIVGLILTHAH
EDHLGGVQYLWHRLKCPIYITTFTANFLKIRLNEYDFAKNIKIHEVKPGSKINLDPFSLEMVPLTHSAPEMQAIMIRTDA
GNILHTGDWKFDNDPILGKKADEELLKSYGDEGVLALVCDSTNVFNKGSSGSEGDVRKSLVDIIAGCPQMVVVSTFASNL
ARLDTIIHAAGLAGRKVVLTGRSLHRMMLAAQESGYLKDIAPLISERDVSRFRREELLVIATGCQGEPMAATAKLASNSH
PSIKLVPKDTMIFSSKIIPGNEKKIFRLFNIFVKAGVEVITERDHFVHVSGHPSIDELQKMYSLIRPNICIPVHGEPVHI
HEHVKLAKKNGIKQVVEVENGSVVLLEPNNAKVISKVENGYLAVDGNYLLPVESPIFKARRRMRESGIVVASVVINKKGL
LAANPMLSMPGLLDPKEDMALVNLIKNDIKELVTIQNKQAKKALSDEQVIEAIKGTIRKTLKQEINKSPVIIVNLEKAVE

Sequences:

>Translated_560_residues
MSSFNIKNHKNDLLFVPLGGSNEIGMNLNLYHYQGQWLMIDCGSGFADDYLPGVDMIIADSSFIEKYKKDIVGLILTHAH
EDHLGGVQYLWHRLKCPIYITTFTANFLKIRLNEYDFAKNIKIHEVKPGSKINLDPFSLEMVPLTHSAPEMQAIMIRTDA
GNILHTGDWKFDNDPILGKKADEELLKSYGDEGVLALVCDSTNVFNKGSSGSEGDVRKSLVDIIAGCPQMVVVSTFASNL
ARLDTIIHAAGLAGRKVVLTGRSLHRMMLAAQESGYLKDIAPLISERDVSRFRREELLVIATGCQGEPMAATAKLASNSH
PSIKLVPKDTMIFSSKIIPGNEKKIFRLFNIFVKAGVEVITERDHFVHVSGHPSIDELQKMYSLIRPNICIPVHGEPVHI
HEHVKLAKKNGIKQVVEVENGSVVLLEPNNAKVISKVENGYLAVDGNYLLPVESPIFKARRRMRESGIVVASVVINKKGL
LAANPMLSMPGLLDPKEDMALVNLIKNDIKELVTIQNKQAKKALSDEQVIEAIKGTIRKTLKQEINKSPVIIVNLEKAVE
>Mature_559_residues
SSFNIKNHKNDLLFVPLGGSNEIGMNLNLYHYQGQWLMIDCGSGFADDYLPGVDMIIADSSFIEKYKKDIVGLILTHAHE
DHLGGVQYLWHRLKCPIYITTFTANFLKIRLNEYDFAKNIKIHEVKPGSKINLDPFSLEMVPLTHSAPEMQAIMIRTDAG
NILHTGDWKFDNDPILGKKADEELLKSYGDEGVLALVCDSTNVFNKGSSGSEGDVRKSLVDIIAGCPQMVVVSTFASNLA
RLDTIIHAAGLAGRKVVLTGRSLHRMMLAAQESGYLKDIAPLISERDVSRFRREELLVIATGCQGEPMAATAKLASNSHP
SIKLVPKDTMIFSSKIIPGNEKKIFRLFNIFVKAGVEVITERDHFVHVSGHPSIDELQKMYSLIRPNICIPVHGEPVHIH
EHVKLAKKNGIKQVVEVENGSVVLLEPNNAKVISKVENGYLAVDGNYLLPVESPIFKARRRMRESGIVVASVVINKKGLL
AANPMLSMPGLLDPKEDMALVNLIKNDIKELVTIQNKQAKKALSDEQVIEAIKGTIRKTLKQEINKSPVIIVNLEKAVE

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 62012; Mature: 61881

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFNIKNHKNDLLFVPLGGSNEIGMNLNLYHYQGQWLMIDCGSGFADDYLPGVDMIIAD
CCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECEEEEEECCCCCCCCCCCCCEEEEEC
SSFIEKYKKDIVGLILTHAHEDHLGGVQYLWHRLKCPIYITTFTANFLKIRLNEYDFAKN
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECEEEEEEECCCCHHCC
IKIHEVKPGSKINLDPFSLEMVPLTHSAPEMQAIMIRTDAGNILHTGDWKFDNDPILGKK
CEEEEECCCCEECCCCCEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCC
ADEELLKSYGDEGVLALVCDSTNVFNKGSSGSEGDVRKSLVDIIAGCPQMVVVSTFASNL
CHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ARLDTIIHAAGLAGRKVVLTGRSLHRMMLAAQESGYLKDIAPLISERDVSRFRREELLVI
HHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEE
ATGCQGEPMAATAKLASNSHPSIKLVPKDTMIFSSKIIPGNEKKIFRLFNIFVKAGVEVI
EECCCCCCCHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCHHEE
TERDHFVHVSGHPSIDELQKMYSLIRPNICIPVHGEPVHIHEHVKLAKKNGIKQVVEVEN
ECCCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHCCCEEEEEECC
GSVVLLEPNNAKVISKVENGYLAVDGNYLLPVESPIFKARRRMRESGIVVASVVINKKGL
CCEEEECCCCCEEEEEECCCEEEECCCEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCC
LAANPMLSMPGLLDPKEDMALVNLIKNDIKELVTIQNKQAKKALSDEQVIEAIKGTIRKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
LKQEINKSPVIIVNLEKAVE
HHHHCCCCCEEEEEEHHHCC
>Mature Secondary Structure 
SSFNIKNHKNDLLFVPLGGSNEIGMNLNLYHYQGQWLMIDCGSGFADDYLPGVDMIIAD
CCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEECEEEEEECCCCCCCCCCCCCEEEEEC
SSFIEKYKKDIVGLILTHAHEDHLGGVQYLWHRLKCPIYITTFTANFLKIRLNEYDFAKN
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEEECEEEEEEECCCCHHCC
IKIHEVKPGSKINLDPFSLEMVPLTHSAPEMQAIMIRTDAGNILHTGDWKFDNDPILGKK
CEEEEECCCCEECCCCCEEEEEEECCCCCCEEEEEEEECCCCEEECCCCCCCCCCCCCCC
ADEELLKSYGDEGVLALVCDSTNVFNKGSSGSEGDVRKSLVDIIAGCPQMVVVSTFASNL
CHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
ARLDTIIHAAGLAGRKVVLTGRSLHRMMLAAQESGYLKDIAPLISERDVSRFRREELLVI
HHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEE
ATGCQGEPMAATAKLASNSHPSIKLVPKDTMIFSSKIIPGNEKKIFRLFNIFVKAGVEVI
EECCCCCCCHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCHHEE
TERDHFVHVSGHPSIDELQKMYSLIRPNICIPVHGEPVHIHEHVKLAKKNGIKQVVEVEN
ECCCCEEEECCCCCHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHHHHHCCCEEEEEECC
GSVVLLEPNNAKVISKVENGYLAVDGNYLLPVESPIFKARRRMRESGIVVASVVINKKGL
CCEEEECCCCCEEEEEECCCEEEECCCEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCC
LAANPMLSMPGLLDPKEDMALVNLIKNDIKELVTIQNKQAKKALSDEQVIEAIKGTIRKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHH
LKQEINKSPVIIVNLEKAVE
HHHHCCCCCEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]