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The map label for this gene is gpsA [H]

Identifier: 229586724

GI number: 229586724

Start: 599586

End: 600563

Strand: Direct

Name: gpsA [H]

Synonym: RAF_ORF0573

Alternate gene names: 229586724

Gene position: 599586-600563 (Clockwise)

Preceding gene: 229586723

Following gene: 229586725

Centisome position: 46.9

GC content: 32.52

Gene sequence:

>978_bases
ATGAACAAATTTAAAAATATTGCGGTGTATGGGGGAGGGAGTTTCGGTACTAGCCTTGCTTCTTTAGCAGCACAAAACTG
TAATAACGTTACTTTATTTTTACGTGATGAGGCAATAGCAAAGGAAATTTTACATAACAAAACTAATGTAAAATATTTAG
GGGATATTAAATTACCTGCTCATTTACAGGCTACTACAAACTTAGATATAATTAAGGATTTTGAACTAATTATTATTGCA
TTGCCGTCTTACGCTTTTGATGACTCAATAAAATTATTAAAAACTCACAGCATTTCTAAAGACAATACTCTTCTAATTGC
AACAAAAGGCTTTGCCCGTAATCCTACCGCATTATTTTCAGATAGGTTAAAAACTCTATTACCGTATAACCCTACAGCGT
TTTTTGTAGGTCCGAATCTAGCAAAAGAACTTGCTAAAAATTTACCTGCTTCGGCAAGTATTGCAAGTTTAGATATAGAT
ATAGCAAATAAAATAGCTTATAACCTAAGTTCAAAAATTTTTACTACTAATGTGTCAAGCGATATTGTAACATTACAGGT
AGCAGGAGCTTTAAAAAATATTTTTGCTATTAAAAGCGGGATTGATTTAGCAAGAAAGCAGGGCGAAAATGCAAGAGCAA
CGCTTATAGTAGCTGCCTTAAAAGAAATTGCTATTTTGTCGAAAGCGTTAGGTGGTATGCAAAAAAATTCTGATATTTTA
TTAGAAGGCGTAGTAGGCGATTTAGTGCTTACTTGTTATTCGTTAGGTTCACGTAATACAAAATTTGGTTATGAACTTGG
AATTAGTAGCGATAAACAGAAATTTTTACAGGAATATAAAGAGCTAGTAGAGGGAAGAGAAGCATTAAAATTAGTTTTGG
ATTTGATAAAAAAATATAATTTACATATGCCTATAATTTCCGAAGTAGCTTCGTGTGTTATTCCTTATGTCATGCCTGCT
TTCGCAGGAATGACATAG

Upstream 100 bases:

>100_bases
AGAAATTCGTTCAATGTCATTCCCGCCTTCGTGAGAATGACATAAACAAGCCAAGCAACGATACCTACAAACCTGTAAGT
GACAAAGAAAAAATAAGCAC

Downstream 100 bases:

>100_bases
GTATCCACGCAACAATGCCTCCGCGGGAATGACATATGACTCCACGCGAGCAATACCAATAAATATGAAAATTTCATATT
AAATTAGATACCTTAAATCA

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPAHLQATTNLDIIKDFELIIIA
LPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFSDRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDID
IANKIAYNLSSKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDIL
LEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYNLHMPIISEVASCVIPYVMPA
FAGMT

Sequences:

>Translated_325_residues
MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPAHLQATTNLDIIKDFELIIIA
LPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFSDRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDID
IANKIAYNLSSKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDIL
LEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYNLHMPIISEVASCVIPYVMPA
FAGMT
>Mature_325_residues
MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPAHLQATTNLDIIKDFELIIIA
LPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFSDRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDID
IANKIAYNLSSKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDIL
LEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYNLHMPIISEVASCVIPYVMPA
FAGMT

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=303, Percent_Identity=25.4125412541254, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24307999, Length=271, Percent_Identity=26.1992619926199, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1790037, Length=307, Percent_Identity=32.2475570032573, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17507425, Length=307, Percent_Identity=24.4299674267101, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136200, Length=303, Percent_Identity=26.4026402640264, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136204, Length=299, Percent_Identity=27.0903010033445, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136202, Length=303, Percent_Identity=26.4026402640264, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35261; Mature: 35261

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPA
CCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCC
HLQATTNLDIIKDFELIIIALPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFS
EEEECCCCCHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCHHHHH
DRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDIDIANKIAYNLSSKIFTTNVSS
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCC
DIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDIL
CEEEEEEHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYN
EHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHMPIISEVASCVIPYVMPAFAGMT
CCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNVKYLGDIKLPA
CCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCEEEEEECCCC
HLQATTNLDIIKDFELIIIALPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFS
EEEECCCCCHHCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCCCHHHHH
DRLKTLLPYNPTAFFVGPNLAKELAKNLPASASIASLDIDIANKIAYNLSSKIFTTNVSS
HHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCEEEEECCCC
DIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSKALGGMQKNSDIL
CEEEEEEHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LEGVVGDLVLTCYSLGSRNTKFGYELGISSDKQKFLQEYKELVEGREALKLVLDLIKKYN
EHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHMPIISEVASCVIPYVMPAFAGMT
CCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA