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The map label for this gene is tlpA [H]

Identifier: 229586669

GI number: 229586669

Start: 535365

End: 536009

Strand: Direct

Name: tlpA [H]

Synonym: RAF_ORF0506

Alternate gene names: 229586669

Gene position: 535365-536009 (Clockwise)

Preceding gene: 229586668

Following gene: 229586670

Centisome position: 41.87

GC content: 30.23

Gene sequence:

>645_bases
ATGACCTTAAGAAATTATAATAAATATCTTATATATATTATAGTATTTTTATTATCTATAATAATTTTTATTCCTAAAAT
TCATGCTAGGCCCTATGAGCAGCCTAAGGATAAATTAGCATTTTTAAGAGGTTCAAGCGTTCCTGATAATATAATTTTTT
TTGATGAAGAAAAAAATCAATATTCTCTTGATCAGTTTGAAGGAAAGACTATATTGTTAGTGTTTTGGGCTACTTGGAGT
GCTCCTTGTGTCAAAGAAATGCCTGACCTTGATATGTTGCAAAAAGATTTTAGGAAATTACCTTTTTCAGTAATTCCGAT
TTCAGAAGATTATCAAGACATAAAAGTTGTGAAAGAATATTTTAAAAGCTATCAAATAAGATATTTGCCGATTTATCATG
ATTATAGAAATGAATTATTTAAAGCCTTATGGGTTGTTAGTTTGCCGACTAGTATATTAATAGACCCAAACGGTAAAATA
GTAACTAGCTTTGTTGGCAATACAAATTGGTATGACGAAAAAGTTAGAGGTACTATTTTGTCTGCCATTTCCGGCAATTA
TCCTGAACCTAAAAATAGTTATAACGCGCAATCTCTGAATAAACCGGCTAAGCCTTTGCTGCCAATAAAAAAGGATGCTC
TATAG

Upstream 100 bases:

>100_bases
CTCTTTCTGCGGTGCTTCTAAAGGCTTTTTTATACCACAACTACATAATGTAAGTGCTAATACGAATAAATAAAATGTCT
TCATTACTATAAATTATTAT

Downstream 100 bases:

>100_bases
TAACTCCAAGTAAATAGACGAAGTGTAATTTGGAAAAGAGCAAGGAGTCTATAAGGCGAGGAGCGGAGCGTATACTTAAT
AGGTGAGTACCGCAGATCTT

Product: Thiol:disulfide interchange protein tlpA

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MTLRNYNKYLIYIIVFLLSIIIFIPKIHARPYEQPKDKLAFLRGSSVPDNIIFFDEEKNQYSLDQFEGKTILLVFWATWS
APCVKEMPDLDMLQKDFRKLPFSVIPISEDYQDIKVVKEYFKSYQIRYLPIYHDYRNELFKALWVVSLPTSILIDPNGKI
VTSFVGNTNWYDEKVRGTILSAISGNYPEPKNSYNAQSLNKPAKPLLPIKKDAL

Sequences:

>Translated_214_residues
MTLRNYNKYLIYIIVFLLSIIIFIPKIHARPYEQPKDKLAFLRGSSVPDNIIFFDEEKNQYSLDQFEGKTILLVFWATWS
APCVKEMPDLDMLQKDFRKLPFSVIPISEDYQDIKVVKEYFKSYQIRYLPIYHDYRNELFKALWVVSLPTSILIDPNGKI
VTSFVGNTNWYDEKVRGTILSAISGNYPEPKNSYNAQSLNKPAKPLLPIKKDAL
>Mature_213_residues
TLRNYNKYLIYIIVFLLSIIIFIPKIHARPYEQPKDKLAFLRGSSVPDNIIFFDEEKNQYSLDQFEGKTILLVFWATWSA
PCVKEMPDLDMLQKDFRKLPFSVIPISEDYQDIKVVKEYFKSYQIRYLPIYHDYRNELFKALWVVSLPTSILIDPNGKIV
TSFVGNTNWYDEKVRGTILSAISGNYPEPKNSYNAQSLNKPAKPLLPIKKDAL

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 25013; Mature: 24882

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRNYNKYLIYIIVFLLSIIIFIPKIHARPYEQPKDKLAFLRGSSVPDNIIFFDEEKNQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCC
YSLDQFEGKTILLVFWATWSAPCVKEMPDLDMLQKDFRKLPFSVIPISEDYQDIKVVKEY
CCHHHHCCCEEEEEEEECCCCCHHHHCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
FKSYQIRYLPIYHDYRNELFKALWVVSLPTSILIDPNGKIVTSFVGNTNWYDEKVRGTIL
HHHCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHH
SAISGNYPEPKNSYNAQSLNKPAKPLLPIKKDAL
HHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLRNYNKYLIYIIVFLLSIIIFIPKIHARPYEQPKDKLAFLRGSSVPDNIIFFDEEKNQ
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCC
YSLDQFEGKTILLVFWATWSAPCVKEMPDLDMLQKDFRKLPFSVIPISEDYQDIKVVKEY
CCHHHHCCCEEEEEEEECCCCCHHHHCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHH
FKSYQIRYLPIYHDYRNELFKALWVVSLPTSILIDPNGKIVTSFVGNTNWYDEKVRGTIL
HHHCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHH
SAISGNYPEPKNSYNAQSLNKPAKPLLPIKKDAL
HHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]