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The map label for this gene is sppA1 [H]

Identifier: 229586670

GI number: 229586670

Start: 536174

End: 537088

Strand: Direct

Name: sppA1 [H]

Synonym: RAF_ORF0507

Alternate gene names: 229586670

Gene position: 536174-537088 (Clockwise)

Preceding gene: 229586669

Following gene: 229586671

Centisome position: 41.94

GC content: 33.55

Gene sequence:

>915_bases
ATGAATGAAGTAAATAAATCAACTATGGCGAATGCTGAATTTGATCAGATAATAACCAAACGACAGATAAGTAAATTAGA
CCAATTATTTGCTTCGGTTTTTGGTAATTCTAAAGAGGTGATTGCCGTTTTACGCCTTAGCGGTGTTATCGGTAAAGTAA
GTACTATGCAATCGGGACTTACGTTAGAATCATTAAATGCACTAATAGAAAAAGCTTTTAAAATAAAGAAATTAAAAGCA
TTATGTTTAATTATTAATTCTCCCGGCGGTTCTCCGGTACAATCTGAACTTATTGCAAAACGTATTCGTGATCTTGCTGA
AGAAAATAAAATAAAAATTTATAGTTTTATTGAAGATATGGCGGCTTCAGGCGGATATTGGCTGGCTTGCAGCGGTGACC
GGATATATGCTTTGCCGAGTTCGGTTATCGGTAGTATCGGAGTAGTATCAAGCGGATTCGGTTTTCATGAAGCAATTAAT
AAACTTGGGATAGAGAGAAGAGTTTATACGGAAGGCAAGAATAAATCAGTATTGGATCCGTTTAAACCTATTAATAAAGA
TGATCTTAAAATTATCAAAGATTTGCAAAAGCAGGTTTATGAACATTTTATAGAATATGTAAAAACAAGAAGAGCAGGGA
AGTTAACTCAGCAAGACGAAATTTTATTTAACGGTGAATTTTGGGCAGGGCAAACGGCGCTTGATTACGGCTTAATTGAT
GGCATAGGTGATATGTATAGCGTAATGAAAGAAAAATTCGGTGATAATATTAAGTTTCAATATCTGTGTGCTAAGCAACC
TTGGCTTAAAAAGAAACTTGGCATGGGAAGTAAGATATTAACCGATAATCTTGCTAATTCTTTAATTGATGCGGTAGAAA
ATAAAATTATTAACGATAAATTTGATATGAAATAA

Upstream 100 bases:

>100_bases
GGAGCGTATACTTAATAGGTGAGTACCGCAGATCTTATAAGACAACATAGCCAATTTTTCAAATGAAACGAGTATATTAA
ATTAAAAATGAGTAAAATTA

Downstream 100 bases:

>100_bases
TATGACAATAACACAAGTTAAAATTAAAAAACTAGAAAATTTTTCCGGCAGTTTGCCGGAATATGCTACAGAGCATAGTG
CGGGGATGGATTTAATAGCC

Product: Signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNEVNKSTMANAEFDQIITKRQISKLDQLFASVFGNSKEVIAVLRLSGVIGKVSTMQSGLTLESLNALIEKAFKIKKLKA
LCLIINSPGGSPVQSELIAKRIRDLAEENKIKIYSFIEDMAASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAIN
KLGIERRVYTEGKNKSVLDPFKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDEILFNGEFWAGQTALDYGLID
GIGDMYSVMKEKFGDNIKFQYLCAKQPWLKKKLGMGSKILTDNLANSLIDAVENKIINDKFDMK

Sequences:

>Translated_304_residues
MNEVNKSTMANAEFDQIITKRQISKLDQLFASVFGNSKEVIAVLRLSGVIGKVSTMQSGLTLESLNALIEKAFKIKKLKA
LCLIINSPGGSPVQSELIAKRIRDLAEENKIKIYSFIEDMAASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAIN
KLGIERRVYTEGKNKSVLDPFKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDEILFNGEFWAGQTALDYGLID
GIGDMYSVMKEKFGDNIKFQYLCAKQPWLKKKLGMGSKILTDNLANSLIDAVENKIINDKFDMK
>Mature_304_residues
MNEVNKSTMANAEFDQIITKRQISKLDQLFASVFGNSKEVIAVLRLSGVIGKVSTMQSGLTLESLNALIEKAFKIKKLKA
LCLIINSPGGSPVQSELIAKRIRDLAEENKIKIYSFIEDMAASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAIN
KLGIERRVYTEGKNKSVLDPFKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDEILFNGEFWAGQTALDYGLID
GIGDMYSVMKEKFGDNIKFQYLCAKQPWLKKKLGMGSKILTDNLANSLIDAVENKIINDKFDMK

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=266, Percent_Identity=28.1954887218045, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787527, Length=162, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 33924; Mature: 33924

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00264 NEUROHYPOPHYS_HORM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVNKSTMANAEFDQIITKRQISKLDQLFASVFGNSKEVIAVLRLSGVIGKVSTMQSGL
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
TLESLNALIEKAFKIKKLKALCLIINSPGGSPVQSELIAKRIRDLAEENKIKIYSFIEDM
CHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAINKLGIERRVYTEGKNKSVLDP
HCCCCEEEEECCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCHHEEECCCCCCCCCC
FKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDEILFNGEFWAGQTALDYGLID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
GIGDMYSVMKEKFGDNIKFQYLCAKQPWLKKKLGMGSKILTDNLANSLIDAVENKIINDK
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
FDMK
CCCC
>Mature Secondary Structure
MNEVNKSTMANAEFDQIITKRQISKLDQLFASVFGNSKEVIAVLRLSGVIGKVSTMQSGL
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
TLESLNALIEKAFKIKKLKALCLIINSPGGSPVQSELIAKRIRDLAEENKIKIYSFIEDM
CHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AASGGYWLACSGDRIYALPSSVIGSIGVVSSGFGFHEAINKLGIERRVYTEGKNKSVLDP
HCCCCEEEEECCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHCCCHHEEECCCCCCCCCC
FKPINKDDLKIIKDLQKQVYEHFIEYVKTRRAGKLTQQDEILFNGEFWAGQTALDYGLID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHH
GIGDMYSVMKEKFGDNIKFQYLCAKQPWLKKKLGMGSKILTDNLANSLIDAVENKIINDK
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
FDMK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA