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The map label for this gene is sdhC

Identifier: 229586366

GI number: 229586366

Start: 168411

End: 168785

Strand: Direct

Name: sdhC

Synonym: RAF_ORF0157

Alternate gene names: 229586366

Gene position: 168411-168785 (Clockwise)

Preceding gene: 229586365

Following gene: 229586367

Centisome position: 13.17

GC content: 34.13

Gene sequence:

>375_bases
ATGACTAAAACCAAACAAGAAATTTATAATAAGCGTCCAACTTCACCGCATTTAACTATATATAAGCCGCAAATAAGTTC
TACATTATCAATTTTGTATCGTATGACCGGCGTAGCTTTGTTTTTTGCGGTGTCAATCTTGGTGTGGTGGTTGATTCTTA
GTAAATATGACAATAATTATTTACAGCTTGCTGAATGCTGTATTATAAAAATATGCTTAGTAGCTGTTAGCTACGCTTGG
TTTTATCATTTATGTAACGGCATTCGGCATTTATTTTGGGATATCGGTTACGGTTTTTCTATAAAATTGGTTAATATCAC
CGGTTGGTGTGTAGTGGTAGGATCTGTATTATTAACGGTATTGTTATGGGTGTAG

Upstream 100 bases:

>100_bases
AGCTTTTAATTTTAAAAATTCGGTATATTTGTATTTTTTAATTACTGGATTCCTGCTTCCGCGGGAATGACATAACCCTT
TGTTTATTTATTAGAAATAT

Downstream 100 bases:

>100_bases
TAATTAAAAATGTCATTGCGAGGAGATGCATAGCATCGACATGGCAATCTCAGAAATAATAACAAATGCCTGAGATTGTT
TCGTCAATTGCTATGCAATT

Product: Succinate dehydrogenase cytochrome b-556 subunit

Products: fumarate; reduced acceptor

Alternate protein names: Cytochrome b-556

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MTKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNYLQLAECCIIKICLVAVSYAW
FYHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTVLLWV

Sequences:

>Translated_124_residues
MTKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNYLQLAECCIIKICLVAVSYAW
FYHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTVLLWV
>Mature_123_residues
TKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNYLQLAECCIIKICLVAVSYAWF
YHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTVLLWV

Specific function: Membrane-anchoring subunit of succinate dehydrogenase (SDH)

COG id: COG2009

COG function: function code C; Succinate dehydrogenase/fumarate reductase, cytochrome b subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome b560 family

Homologues:

Organism=Homo sapiens, GI4506863, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323765, Length=123, Percent_Identity=34.9593495934959, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550736, Length=133, Percent_Identity=36.8421052631579, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DHSC_RICCN (Q92J99)

Other databases:

- EMBL:   AE006914
- PIR:   H97720
- RefSeq:   NP_359805.1
- ProteinModelPortal:   Q92J99
- SMR:   Q92J99
- GeneID:   928024
- GenomeReviews:   AE006914_GR
- KEGG:   rco:RC0168
- NMPDR:   fig|272944.1.peg.168
- OMA:   TWALMHH
- ProtClustDB:   CLSK870757
- BioCyc:   RCON272944:RC0168-MONOMER
- GO:   GO:0006810
- InterPro:   IPR018495
- InterPro:   IPR014314
- InterPro:   IPR014361
- InterPro:   IPR000701
- PIRSF:   PIRSF000178
- TIGRFAMs:   TIGR02970

Pfam domain/function: PF01127 Sdh_cyt

EC number: 1.3.99.1

Molecular weight: Translated: 14341; Mature: 14210

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01000 SDH_CYT_1; PS01001 SDH_CYT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fd66b10)-; HASH(0x20dc6d80)-; HASH(0x1fdd85a0)-;

Cys/Met content:

4.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNY
CCCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LQLAECCIIKICLVAVSYAWFYHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
LLWV
HHHH
>Mature Secondary Structure 
TKTKQEIYNKRPTSPHLTIYKPQISSTLSILYRMTGVALFFAVSILVWWLILSKYDNNY
CCCHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LQLAECCIIKICLVAVSYAWFYHLCNGIRHLFWDIGYGFSIKLVNITGWCVVVGSVLLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHH
LLWV
HHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11557893