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The map label for this gene is alr

Identifier: 229586333

GI number: 229586333

Start: 124151

End: 125218

Strand: Direct

Name: alr

Synonym: RAF_ORF0118

Alternate gene names: 229586333

Gene position: 124151-125218 (Clockwise)

Preceding gene: 229586332

Following gene: 229586334

Centisome position: 9.71

GC content: 34.74

Gene sequence:

>1068_bases
ATGAGCTTGTGTACTGTAGAAATAAATCTATCTACAATAAAAAATAATTACCTTTTATTACAAGATATTTGCAAAACCTC
ATTAGTCGGTGCTGCCGTTAAAGCTAACGGTTACGGTCTTGGAGCAGTACAAATTTCTAAAGCTTTAATAGAAGAAAATT
GTAGGCATTTTTTTGTGGCCTCAAGTGAAGAAGGAGTGAATTTACGCAACGCTTTAGGATTAGATGTTAATATTTTAGTT
CTTAACGGCGTTTTTGAACATGATGCTTTAGAGCTGATAGAATATAATTTAACACCTGTCCTAAATAACTTAAAACAAAT
AGAAATTTGGCAAAAATTTAGTAATTTGAAAAACCGATTATTGTCTTGTTATTTACATTTCAATACGGGGATTAATCGTC
TTGGCTTAAGCTCTGATGAGATAGAGCAGCTCATTAATGATCGTGATTTGTTAAAAGGGCTAGATTTACAATATATTATA
AGCCATCTAGCTATATCCGAGGAAATAGATAATCCTTATAATCTAGAACAATTAAACAGATTTAAAGCTTATTTACAATA
TTTCCCAAACGTCAAAGCAAGCCTTGCTAATTCCGGCGGCATATTTTTAGGACAGGATTACCATTTTGATTTAGCAAGAC
CAGGGGCAGCCTTATATGGTCTTAATCCCTTAACAAAGAATCCCGTAACCTTAAAAGCTCCTATAATTCACTTACAGAAT
TTGACACTAGATAGCCATATCGGTTATAATATGACTTTTACAACTAAGCGTGATAGTGTCATTGCAACGTTACCGCTTGG
TTATGCCGATGGGTTTAGTCGTAATTTTAGCAATCAAGGCGAAGTATTTATTAACAGTCGCAGCGTTCCTATAGTAGGGC
GAGTATCGATGGATTTAATAAATATCGATGTTACCGATCTACCACCATCCGAGATTTTTCTAGGGCAGGAAGCGGAAATT
ATCGGAAATTATTGCACGCCCGATAAAATAGCGAGTATTATAGGTACTATCGGGTATGAGGTATTAACTAACCTTGGTAG
TAGATATAAAAGAAAGTATATCGGGTAG

Upstream 100 bases:

>100_bases
CAATATTTTTATCACGGATACTAAAAACAAGTGACTTATCTACAAAATTTCATATAATACCCGTATTGTCTATCATCGTA
AAAGAGTTAATAAATATACT

Downstream 100 bases:

>100_bases
ATATCTGTGTCATACACGGTATCCAGAAAAAAATTAAAAAAGACTGGATCCCGCGATCAAGTCGCGGGGATGACATTAGA
GGTTACTGGATTCCTGCTTG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVASSEEGVNLRNALGLDVNILV
LNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLSCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYII
SHLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQN
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEI
IGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG

Sequences:

>Translated_355_residues
MSLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVASSEEGVNLRNALGLDVNILV
LNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLSCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYII
SHLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQN
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEI
IGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG
>Mature_354_residues
SLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVASSEEGVNLRNALGLDVNILVL
NGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLSCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIIS
HLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQNL
TLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEII
GNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=366, Percent_Identity=30.0546448087432, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=29.2613636363636, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_RICAE (C3PMD1)

Other databases:

- EMBL:   CP001612
- RefSeq:   YP_002844834.1
- ProteinModelPortal:   C3PMD1
- GeneID:   7815369
- GenomeReviews:   CP001612_GR
- KEGG:   raf:RAF_ORF0118
- OMA:   YCTPDKI
- ProtClustDB:   PRK00053
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 39479; Mature: 39348

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 34-34 ACT_SITE 249-249

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVA
CCEEEEEEEEEEECCCEEEHHHHHHHHHHHHEEECCCCEEHHHHHHHHHHHCCCCEEEEE
SSEEGVNLRNALGLDVNILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRL
CCCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNR
HEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
FKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQN
HHHHHHHCCCCCEECCCCCCEEEECCCEEECCCCCCEEECCCCCCCCCEEEEECEEEEEC
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLI
CEECCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
NIDVTDLPPSEIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG
EEEECCCCHHHEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLCTVEINLSTIKNNYLLLQDICKTSLVGAAVKANGYGLGAVQISKALIEENCRHFFVA
CEEEEEEEEEEECCCEEEHHHHHHHHHHHHEEECCCCEEHHHHHHHHHHHCCCCEEEEE
SSEEGVNLRNALGLDVNILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRL
CCCCCCCHHHHCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LSCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNR
HEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
FKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQN
HHHHHHHCCCCCEECCCCCCEEEECCCEEECCCCCCEEECCCCCCCCCEEEEECEEEEEC
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLI
CEECCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEEEEE
NIDVTDLPPSEIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTNLGSRYKRKYIG
EEEECCCCHHHEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA