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The map label for this gene is sdhB [H]

Identifier: 229586280

GI number: 229586280

Start: 62463

End: 63248

Strand: Direct

Name: sdhB [H]

Synonym: RAF_ORF0063

Alternate gene names: 229586280

Gene position: 62463-63248 (Clockwise)

Preceding gene: 229586279

Following gene: 229586281

Centisome position: 4.89

GC content: 37.02

Gene sequence:

>786_bases
ATGGCAGAGTTAAGGTTACCGCCAAATTCAGTAGTAAAAAAAGGTAGAGAGCATAAAGAACAAGAGGAAATGCTTAAACC
TAGAAAGATAAAAATTTATAGGTATGACCCTGATCTTGATAAGAATCCTACTATCGATAGTTTTGAGATAGATTTAAGCA
AAACCGGACCGATGGTTTTAGATGCTTTAATTAAAATCAAAAACGACATCGATTCTACTTTAACTTTTAGGCGTTCTTGT
CGGGAAGGAATTTGCGGTAGTTGTGCAATGAATATTGACGGTACAAATACTTTAGCATGCATAAAACCAATAGAAGATAT
ATCAGGCGATATCAAAATCTATCCGCTTCCTCATATGAAAGTAGTGAAAGATTTAGTACCTGATATGTCGCATTTTTATG
CACAATACGAATCTATAGAACCTTGGCTCAAAACCGATAGCCCTACCCCTTCAAACTCTGAAAGGTTACAGTCGATTAAA
GACCGAGAAAAGCTTGACGGTTTATATGAGTGTATATTATGTGCTTGCTGTTCTACTTCTTGTCCTAGCTATTGGTGGAA
CGGTGATAAATATTTGGGTCCTGCGATTTTACTACAAGCATATAGATGGATTGCCGATTCAAGGGATGATAATACCGGTG
AACGTCTTGAAGCTTTAGAAGACCCATTTAAGCTTTACCGTTGTCATACGATTATGAACTGTACTAAGACCTGCCCGAAA
GGCTTAAATCCTGCTAAAGCTATCGGTAAAATAAAAAGTTTAATTGCAGAACGTCACGGTTTGTGA

Upstream 100 bases:

>100_bases
CTAGAGATATTAATGTCATCCACGTAACAGGTATGAAAGATTGTGAATTAGCTAATTATTTTGTATAGTTCTAAAAACAA
ATTTTAAGAGAGTGCTTAAA

Downstream 100 bases:

>100_bases
TTCTTAATTAATTATTTTTAAAAATGATAAAATAATGAAAAAAGCAATTATTTTCTGTTGATTGTAATAATACCATGATA
CAAGGTGATATGAATTATTG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAELRLPPNSVVKKGREHKEQEEMLKPRKIKIYRYDPDLDKNPTIDSFEIDLSKTGPMVLDALIKIKNDIDSTLTFRRSC
REGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIK
DREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGERLEALEDPFKLYRCHTIMNCTKTCPK
GLNPAKAIGKIKSLIAERHGL

Sequences:

>Translated_261_residues
MAELRLPPNSVVKKGREHKEQEEMLKPRKIKIYRYDPDLDKNPTIDSFEIDLSKTGPMVLDALIKIKNDIDSTLTFRRSC
REGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIK
DREKLDGLYECILCACCSTSCPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGERLEALEDPFKLYRCHTIMNCTKTCPK
GLNPAKAIGKIKSLIAERHGL
>Mature_260_residues
AELRLPPNSVVKKGREHKEQEEMLKPRKIKIYRYDPDLDKNPTIDSFEIDLSKTGPMVLDALIKIKNDIDSTLTFRRSCR
EGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIKD
REKLDGLYECILCACCSTSCPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGERLEALEDPFKLYRCHTIMNCTKTCPKG
LNPAKAIGKIKSLIAERHGL

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=70.6896551724138, Blast_Score=349, Evalue=1e-96,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=53.8135593220339, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI1790596, Length=231, Percent_Identity=33.7662337662338, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=66.2337662337662, Blast_Score=329, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6322987, Length=231, Percent_Identity=64.0692640692641, Blast_Score=315, Evalue=7e-87,
Organism=Drosophila melanogaster, GI17137106, Length=249, Percent_Identity=63.0522088353414, Blast_Score=341, Evalue=3e-94,
Organism=Drosophila melanogaster, GI24643156, Length=235, Percent_Identity=63.4042553191489, Blast_Score=313, Evalue=5e-86,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29676; Mature: 29544

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELRLPPNSVVKKGREHKEQEEMLKPRKIKIYRYDPDLDKNPTIDSFEIDLSKTGPMVL
CCCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHH
DALIKIKNDIDSTLTFRRSCREGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCHHHCCCCEEEEECCHHH
VVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIKDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGERLEALEDPFKLYRCHTIMNCTKTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIGKIKSLIAERHGL
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AELRLPPNSVVKKGREHKEQEEMLKPRKIKIYRYDPDLDKNPTIDSFEIDLSKTGPMVL
CCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHH
DALIKIKNDIDSTLTFRRSCREGICGSCAMNIDGTNTLACIKPIEDISGDIKIYPLPHMK
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEECCHHHCCCCEEEEECCHHH
VVKDLVPDMSHFYAQYESIEPWLKTDSPTPSNSERLQSIKDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNGDKYLGPAILLQAYRWIADSRDDNTGERLEALEDPFKLYRCHTIMNCTKTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLNPAKAIGKIKSLIAERHGL
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA