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The map label for this gene is ycgM [C]

Identifier: 227828778

GI number: 227828778

Start: 2370078

End: 2370992

Strand: Direct

Name: ycgM [C]

Synonym: M1425_2552

Alternate gene names: 227828778

Gene position: 2370078-2370992 (Clockwise)

Preceding gene: 227828777

Following gene: 227828782

Centisome position: 90.85

GC content: 36.83

Gene sequence:

>915_bases
ATGGTTAAGATACTACTATTTTCTCCAAATCCTAATGAATTTAAGAGAGTTGGCGTTTATGAGAACAATAAGGTCATTGA
CCTTGTAAAGGCTTATGAACTATTGTATGATGCTAAGCCCCCAAATTGGTTTTACGATACTAAGGATCTAATTGAAGGTG
GAGATGGTGCAATGCTAATGATAAAGACTATTTTAGATAATTTGAGAGGTAATGAGGATAAAGTGTCTTATGATCCAGAG
AAGATCTTCTATTACCCACCAATTACAAATCCAGAGAAGATCTTCCTATTAGCCGTTAATTACAAGGCTCATGGTAAGGA
GACTAACAATGAGCCACCTAAGGAACCTTACATATTTACCAAGTTCTCAAATGCGTTAATTGGCCATAATCAACCAATAT
TATATCCAAAGGCTTCAAATAAGGTTGACTACGAGGTTGAGCTTGCAGTTATAATTGGGAAAAAAGGGAAGTATATAAGA
AAGGAAAGAGTCTCTGATTACGTATTTGGTTACACAGTATTTAACGATATTAGTTATAGGGATAAACAATTTCCATCAGA
AATGCCCTACGGTATGAGATGGGTTCACGGTAAAGGTATGGACACTGGGGCTCCAATGGGGCCATGGATAGTTACCAAGG
ACGAAATACCAAACCCCTATGAATTGAGATTAACCTTAAGGGTTAACGGCGAGGTTAGGCAAGATGCTTACGCTGAGGAT
ATGATATTCAAGATTGACGAAATAATTGAGTACTTATCAAATGGTATAACACTTAAACCTGGAGATGTAATATCAACTGG
AACTCCACCCGGAGTCGGATTAGCTAGTGGTAAATTTTTGAAAGCTGGAGATGTAATTGAAGCTGAGATAAGTAAGATAG
GTGTCTTGAGGAATTATTTAGTAAAAGAGGAATAA

Upstream 100 bases:

>100_bases
GAGTCCAACAATTCTGAGAGTTCACGTTAATTCTAATAGTATACCTTCTAGATTGTTAATGAAAAGATAGCTATTTATAA
TAAAATAAGGTATTTTACTT

Downstream 100 bases:

>100_bases
AATCAGATCTTTATTATGGCGTAATTTATCCCCAAATATGCTAGAAAGAACAATGGTAATATAAGGTCTGGTATATCGAA
GACGACCTCACTTATCCATA

Product: 5-oxopent-3-ene-1,2,5-tricarboxylatede carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MVKILLFSPNPNEFKRVGVYENNKVIDLVKAYELLYDAKPPNWFYDTKDLIEGGDGAMLMIKTILDNLRGNEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEVELAVIIGKKGKYIR
KERVSDYVFGYTVFNDISYRDKQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDVISTGTPPGVGLASGKFLKAGDVIEAEISKIGVLRNYLVKEE

Sequences:

>Translated_304_residues
MVKILLFSPNPNEFKRVGVYENNKVIDLVKAYELLYDAKPPNWFYDTKDLIEGGDGAMLMIKTILDNLRGNEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEVELAVIIGKKGKYIR
KERVSDYVFGYTVFNDISYRDKQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDVISTGTPPGVGLASGKFLKAGDVIEAEISKIGVLRNYLVKEE
>Mature_304_residues
MVKILLFSPNPNEFKRVGVYENNKVIDLVKAYELLYDAKPPNWFYDTKDLIEGGDGAMLMIKTILDNLRGNEDKVSYDPE
KIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFTKFSNALIGHNQPILYPKASNKVDYEVELAVIIGKKGKYIR
KERVSDYVFGYTVFNDISYRDKQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
MIFKIDEIIEYLSNGITLKPGDVISTGTPPGVGLASGKFLKAGDVIEAEISKIGVLRNYLVKEE

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=224, Percent_Identity=43.3035714285714, Blast_Score=198, Evalue=5e-51,
Organism=Homo sapiens, GI40786394, Length=224, Percent_Identity=42.8571428571429, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI66348062, Length=197, Percent_Identity=38.0710659898477, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI13654274, Length=197, Percent_Identity=38.0710659898477, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI215422413, Length=197, Percent_Identity=38.0710659898477, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787428, Length=190, Percent_Identity=38.9473684210526, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17557057, Length=195, Percent_Identity=38.4615384615385, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=233, Percent_Identity=31.7596566523605, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=43.75, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=37.1559633027523, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=37.3205741626794, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 34582; Mature: 34582

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILLFSPNPNEFKRVGVYENNKVIDLVKAYELLYDAKPPNWFYDTKDLIEGGDGAMLM
CEEEEEECCCCCHHEEECEECCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEE
IKTILDNLRGNEDKVSYDPEKIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFT
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECEECCCCCCCCCCCCCEEEE
KFSNALIGHNQPILYPKASNKVDYEVELAVIIGKKGKYIRKERVSDYVFGYTVFNDISYR
EECCCEECCCCCEEEECCCCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEEEEECCCCCC
DKQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCHHHHHH
MIFKIDEIIEYLSNGITLKPGDVISTGTPPGVGLASGKFLKAGDVIEAEISKIGVLRNYL
HHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
VKEE
HCCC
>Mature Secondary Structure
MVKILLFSPNPNEFKRVGVYENNKVIDLVKAYELLYDAKPPNWFYDTKDLIEGGDGAMLM
CEEEEEECCCCCHHEEECEECCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCEEE
IKTILDNLRGNEDKVSYDPEKIFYYPPITNPEKIFLLAVNYKAHGKETNNEPPKEPYIFT
HHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECEECCCCCCCCCCCCCEEEE
KFSNALIGHNQPILYPKASNKVDYEVELAVIIGKKGKYIRKERVSDYVFGYTVFNDISYR
EECCCEECCCCCEEEECCCCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEEEEECCCCCC
DKQFPSEMPYGMRWVHGKGMDTGAPMGPWIVTKDEIPNPYELRLTLRVNGEVRQDAYAED
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCCCHHHHHH
MIFKIDEIIEYLSNGITLKPGDVISTGTPPGVGLASGKFLKAGDVIEAEISKIGVLRNYL
HHHHHHHHHHHHHCCCEECCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
VKEE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]