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The map label for this gene is dppC [H]

Identifier: 227828560

GI number: 227828560

Start: 2121776

End: 2122747

Strand: Direct

Name: dppC [H]

Synonym: M1425_2311

Alternate gene names: 227828560

Gene position: 2121776-2122747 (Clockwise)

Preceding gene: 227828559

Following gene: 227828561

Centisome position: 81.33

GC content: 35.6

Gene sequence:

>972_bases
ATGGCTAGCAGAAAGTTATTTACTTTTAATTTAAAAATAGACAAGTACGGTCCGGTTTATAATCTAATAAGAGGTGTGTG
GGAACAAAGAGTATCAAGAGTTGGGTTCTATATACTACTAGGGATAATAGTATTTTCCTTAATAGGCATATTTTATACTC
CATATAATCCAAGCGCGACTAACTTTCCTAGGGATCTACCACCCTCACCTCAACACCTATTAGGCACGGATGATTATGGC
CATGATATTTTTTCTCAACTTTTAGTAGGTGGATTTCCAGTAATTGGAGTAGGTTTTGCTGTAGGATTAATAGGTACGCT
AATAGCTATCCTCATAGGAATAACTGCAGGATTATATGCAGAGACAATGATTGATAGAGTATTAAGTGCAATAACTCAGA
TTTTCTTAATAATACCCGGTATTTTGATTATCGAATTAATAGGAGCATATCTAGGAGCAGTACAGTTTAAATTAGGATAT
ATAACAATTTTGTTCGCCCTTTCATTAACTGGCTGGGCATGGGGTGCTAGAGTGCTGAGATCTTTAGTGTTATCGTTAAG
GAGGAGAGAGTATATATTATCTTCTGATCTTATTGGCGAGTCTAAATTAAGTATAATTTTTAATCAAATAATACCTAATA
ACCTACCGTTCATAGCTTCAAACTTCTTCTTTACTGCAATTTATGGTATCGCTGGCTTTACATTCATTTATTATTTTGGA
TTGGGTAGTCTAACACAAGTCAATTGGGGAACCATGCTCTATTGGTCTTTAGGAGGAGAGGCTTATCTAAGAGGATTATG
GTGGTGGTACATTCCCCCTGGACTCATGATTGGTTTAGTGGCTTTTTCATTCGCTTTAATTAACATAGGGATTGATAGAG
TTGCGAATCCAAGGCTAAGAATATGGGACGTAAAGAAATATATGAAAAAAATAGAAAAAGCAAAAGAGAAGGAGGAGGTG
TTGACTAGATGA

Upstream 100 bases:

>100_bases
ATGCTAGTCACTGCGATGGTATTAAGTAATTTCGTCGCCGATATAATTTACACAATTATAGATCCTAGGACAAGTCAAGA
GGAGACGGAGGGTGTATAAG

Downstream 100 bases:

>100_bases
GTGAAATCTCGATATCAGTAAAAAACCTAAACGTGGGTTACTTATCAGACTATGGTATAATAAAAGTCCTAAGAGATGTC
AGTATTGACATTCCAGAAAG

Product: binding-protein-dependent transporters inner membrane component

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MASRKLFTFNLKIDKYGPVYNLIRGVWEQRVSRVGFYILLGIIVFSLIGIFYTPYNPSATNFPRDLPPSPQHLLGTDDYG
HDIFSQLLVGGFPVIGVGFAVGLIGTLIAILIGITAGLYAETMIDRVLSAITQIFLIIPGILIIELIGAYLGAVQFKLGY
ITILFALSLTGWAWGARVLRSLVLSLRRREYILSSDLIGESKLSIIFNQIIPNNLPFIASNFFFTAIYGIAGFTFIYYFG
LGSLTQVNWGTMLYWSLGGEAYLRGLWWWYIPPGLMIGLVAFSFALINIGIDRVANPRLRIWDVKKYMKKIEKAKEKEEV
LTR

Sequences:

>Translated_323_residues
MASRKLFTFNLKIDKYGPVYNLIRGVWEQRVSRVGFYILLGIIVFSLIGIFYTPYNPSATNFPRDLPPSPQHLLGTDDYG
HDIFSQLLVGGFPVIGVGFAVGLIGTLIAILIGITAGLYAETMIDRVLSAITQIFLIIPGILIIELIGAYLGAVQFKLGY
ITILFALSLTGWAWGARVLRSLVLSLRRREYILSSDLIGESKLSIIFNQIIPNNLPFIASNFFFTAIYGIAGFTFIYYFG
LGSLTQVNWGTMLYWSLGGEAYLRGLWWWYIPPGLMIGLVAFSFALINIGIDRVANPRLRIWDVKKYMKKIEKAKEKEEV
LTR
>Mature_322_residues
ASRKLFTFNLKIDKYGPVYNLIRGVWEQRVSRVGFYILLGIIVFSLIGIFYTPYNPSATNFPRDLPPSPQHLLGTDDYGH
DIFSQLLVGGFPVIGVGFAVGLIGTLIAILIGITAGLYAETMIDRVLSAITQIFLIIPGILIIELIGAYLGAVQFKLGYI
TILFALSLTGWAWGARVLRSLVLSLRRREYILSSDLIGESKLSIIFNQIIPNNLPFIASNFFFTAIYGIAGFTFIYYFGL
GSLTQVNWGTMLYWSLGGEAYLRGLWWWYIPPGLMIGLVAFSFALINIGIDRVANPRLRIWDVKKYMKKIEKAKEKEEVL
TR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789889, Length=260, Percent_Identity=29.2307692307692, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787760, Length=270, Percent_Identity=31.1111111111111, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787054, Length=290, Percent_Identity=26.551724137931, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789964, Length=264, Percent_Identity=29.5454545454545, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787549, Length=238, Percent_Identity=27.7310924369748, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788505, Length=215, Percent_Identity=26.9767441860465, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36304; Mature: 36172

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRKLFTFNLKIDKYGPVYNLIRGVWEQRVSRVGFYILLGIIVFSLIGIFYTPYNPSAT
CCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NFPRDLPPSPQHLLGTDDYGHDIFSQLLVGGFPVIGVGFAVGLIGTLIAILIGITAGLYA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETMIDRVLSAITQIFLIIPGILIIELIGAYLGAVQFKLGYITILFALSLTGWAWGARVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVLSLRRREYILSSDLIGESKLSIIFNQIIPNNLPFIASNFFFTAIYGIAGFTFIYYFG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
LGSLTQVNWGTMLYWSLGGEAYLRGLWWWYIPPGLMIGLVAFSFALINIGIDRVANPRLR
CCCCEEECCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
IWDVKKYMKKIEKAKEKEEVLTR
EEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASRKLFTFNLKIDKYGPVYNLIRGVWEQRVSRVGFYILLGIIVFSLIGIFYTPYNPSAT
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC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EEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377; 3145906 [H]