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The map label for this gene is dppB [H]

Identifier: 227828559

GI number: 227828559

Start: 2120662

End: 2121774

Strand: Direct

Name: dppB [H]

Synonym: M1425_2310

Alternate gene names: 227828559

Gene position: 2120662-2121774 (Clockwise)

Preceding gene: 227828556

Following gene: 227828560

Centisome position: 81.29

GC content: 34.86

Gene sequence:

>1113_bases
ATGATTTATACTAAATTAACAAAATTGTTGTTAATACTCATATTTATATATCTCTATTTCAAAGATTCTAATAGTGGGTC
TCTAGTGAGACGAGATTTCTTGATCAAAAGGGGTATATATTACATTATAGTTTGGTTTGTTGGAATTACAATAGATTTTG
TCCTTCCTAGGCTAATACCTGGTAGTGCCTTGGCCAGCATAATTTATAGTAGAATTGGTGGAGCTGGAGCCAATTATGGA
CAAGATATCCAACAAGAGATTCAAATTCTTGTTCAGCAATTAGGTTTAGCTCAGTATCAACAACCTCTTTATATTCAGTA
TTTTAATTACTTAAAAGAAATAGTTACACTGAATTTCGGTGTTTCTCTTACCGAATTCCCAGTATCTGTAAGCACAATAA
TAACTGAAGCTGCTCCTTGGACTTTTGGTATAGTAATACCAGCTATTGTAGCTTCTTTCTTCATAGGTAATTTGCTTGGC
AGAGTGGCTGCTTTGTCAAGAGGTAAAATAAGTGACTACGCCATATTGGGACTCATGATGTTTTTATATACGTTTCCGGT
TTTTGTTACTGGTGAGATTTTAATAGAAGTACTAGCAATTGATCTTCACATATTCCCTACAGGTGGTCAGTATAATACCT
TTCAATTTCTCAAACCTACTATGAGTTTACCCTTTGTGTGGTCCGTAATATATCATGCAATATTACCCACATTAACACTA
ATTATCTTTTCCCTAGCTGGTTGGATAATGGGAATGAGGAATAATATGATACCCATTTTACAAGAGGATTATATGAATTA
TTATAGGTTAATGGGGGTATCAGAAAAAATGGTTGCAAGTAAGGCCTATAGGTTAGCATTATTACCTAACTTTACCAGTT
TCTCCATTTCCTTAGGATACTCTGTGTTGGGTGCTGTTGCGATAGAGTATTTATTTAATTATGCAGGTTTGGGCTACTTC
TTTAATCAAGCCATTACCGGTTTGGATTACCCGTTACTAAGCGGAATATTTTTCATGCTAGTCACTGCGATGGTATTAAG
TAATTTCGTCGCCGATATAATTTACACAATTATAGATCCTAGGACAAGTCAAGAGGAGACGGAGGGTGTATAA

Upstream 100 bases:

>100_bases
GTGCGACAAAATTTTTTGAAAAAGGATTTAGAAATTGCGACATCTTCTCTTCGTCAACAGTCAAATCATATGTAGAATTG
AAAATAAATGAATACTTTAT

Downstream 100 bases:

>100_bases
GATGGCTAGCAGAAAGTTATTTACTTTTAATTTAAAAATAGACAAGTACGGTCCGGTTTATAATCTAATAAGAGGTGTGT
GGGAACAAAGAGTATCAAGA

Product: binding-protein-dependent transporters inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MIYTKLTKLLLILIFIYLYFKDSNSGSLVRRDFLIKRGIYYIIVWFVGITIDFVLPRLIPGSALASIIYSRIGGAGANYG
QDIQQEIQILVQQLGLAQYQQPLYIQYFNYLKEIVTLNFGVSLTEFPVSVSTIITEAAPWTFGIVIPAIVASFFIGNLLG
RVAALSRGKISDYAILGLMMFLYTFPVFVTGEILIEVLAIDLHIFPTGGQYNTFQFLKPTMSLPFVWSVIYHAILPTLTL
IIFSLAGWIMGMRNNMIPILQEDYMNYYRLMGVSEKMVASKAYRLALLPNFTSFSISLGYSVLGAVAIEYLFNYAGLGYF
FNQAITGLDYPLLSGIFFMLVTAMVLSNFVADIIYTIIDPRTSQEETEGV

Sequences:

>Translated_370_residues
MIYTKLTKLLLILIFIYLYFKDSNSGSLVRRDFLIKRGIYYIIVWFVGITIDFVLPRLIPGSALASIIYSRIGGAGANYG
QDIQQEIQILVQQLGLAQYQQPLYIQYFNYLKEIVTLNFGVSLTEFPVSVSTIITEAAPWTFGIVIPAIVASFFIGNLLG
RVAALSRGKISDYAILGLMMFLYTFPVFVTGEILIEVLAIDLHIFPTGGQYNTFQFLKPTMSLPFVWSVIYHAILPTLTL
IIFSLAGWIMGMRNNMIPILQEDYMNYYRLMGVSEKMVASKAYRLALLPNFTSFSISLGYSVLGAVAIEYLFNYAGLGYF
FNQAITGLDYPLLSGIFFMLVTAMVLSNFVADIIYTIIDPRTSQEETEGV
>Mature_370_residues
MIYTKLTKLLLILIFIYLYFKDSNSGSLVRRDFLIKRGIYYIIVWFVGITIDFVLPRLIPGSALASIIYSRIGGAGANYG
QDIQQEIQILVQQLGLAQYQQPLYIQYFNYLKEIVTLNFGVSLTEFPVSVSTIITEAAPWTFGIVIPAIVASFFIGNLLG
RVAALSRGKISDYAILGLMMFLYTFPVFVTGEILIEVLAIDLHIFPTGGQYNTFQFLKPTMSLPFVWSVIYHAILPTLTL
IIFSLAGWIMGMRNNMIPILQEDYMNYYRLMGVSEKMVASKAYRLALLPNFTSFSISLGYSVLGAVAIEYLFNYAGLGYF
FNQAITGLDYPLLSGIFFMLVTAMVLSNFVADIIYTIIDPRTSQEETEGV

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=351, Percent_Identity=26.2108262108262, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787053, Length=330, Percent_Identity=28.4848484848485, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787497, Length=334, Percent_Identity=25.1497005988024, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789888, Length=269, Percent_Identity=26.3940520446097, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788504, Length=370, Percent_Identity=25.6756756756757, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=28.955223880597, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787550, Length=278, Percent_Identity=23.021582733813, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41618; Mature: 41618

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHCCCC
>Mature Secondary Structure
MIYTKLTKLLLILIFIYLYFKDSNSGSLVRRDFLIKRGIYYIIVWFVGITIDFVLPRLIP
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GSALASIIYSRIGGAGANYGQDIQQEIQILVQQLGLAQYQQPLYIQYFNYLKEIVTLNFG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
VSLTEFPVSVSTIITEAAPWTFGIVIPAIVASFFIGNLLGRVAALSRGKISDYAILGLMM
CCHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FLYTFPVFVTGEILIEVLAIDLHIFPTGGQYNTFQFLKPTMSLPFVWSVIYHAILPTLTL
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHH
IIFSLAGWIMGMRNNMIPILQEDYMNYYRLMGVSEKMVASKAYRLALLPNFTSFSISLGY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCHHHHHHHH
SVLGAVAIEYLFNYAGLGYFFNQAITGLDYPLLSGIFFMLVTAMVLSNFVADIIYTIIDP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RTSQEETEGV
CCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]