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The map label for this gene is thiL [H]

Identifier: 227828162

GI number: 227828162

Start: 1741096

End: 1742046

Strand: Direct

Name: thiL [H]

Synonym: M1425_1900

Alternate gene names: 227828162

Gene position: 1741096-1742046 (Clockwise)

Preceding gene: 227828161

Following gene: 227828163

Centisome position: 66.74

GC content: 30.91

Gene sequence:

>951_bases
GTGAAACTTAAAGATATAGGCGAGCACGAGTTCATCAAGAGATATATTAAGAATTACGTGGATATTAAACTATTAGACGA
TGTATTCATTCATGAAAAAAGAGGATATAAGGTGGATGGATTCAAGCTATCCTATACTTTTCCGTTTATGTCACTCTACG
ATATTGGATGGAAAGCGATTTCAGCCTCTACCAGTGACATTATAGCGAAGGGAGTCAAACCGGAATTTTATTTAATTTCA
TTGGGTTTACCACCAGATTTTGATGTGAATAAAGCAGAAGAACTTATTAAAGGTATATCTGATGCTATCCATTATTATGG
AGGAAGGTATATAGGAGGGGATTTAAATGATTCTGATTCTAGTGGTTGGGTTGATGTTTTTGTAGAAGGAGAAGTTTTAT
GTGATATTAGCAATAAAGATATTGATGATGGCGATCTTTTAGTAGTTGGCGATTATATTGGTTATACCACGAATGTTTTT
ATTTCCTATATAAACAATTTTAATATACAGATCTTGCCAGAATCATTACTTAAAGTAAAACATCCTATTGTTAGAAAGTC
ATTACTATTTTTTATGAAAAAATATTGTAAGTTCATTAAGTATTCTACGGACATTAGTGATGGTCTTATGGTATCTTTAT
ACAAAATAATCGATAATTTCGATTTAGGGATAAATATTACCGAAATTCCAATAGATAAAAACGTGTTCAATACGCTAAAG
CTTCGTTTAAATTTAACTGAACTCGATATTTTAAAGTATGCCGGAGAGGAGTTTTTGCCCTTGCTAATTATAGACAAAAA
TTCGCCGGTAAAGGAAATGTTAAATGAACTTCAATATCTAGCATTTAATCCGTTAATTATCGGGCAAGTTATCCATGAAA
AGAAAGCAGTCATATATAAAAATACATTCATTAAAAATACTGGATGGGATAATTTTATAGGTTGGTATTAA

Upstream 100 bases:

>100_bases
AAGTGAGATAGCCGGTGGTCGCGGGTTCGAATCCCGCCGGCGGCTTTAAAGCATTATTTTTGAGAAATTAAATAAGACTT
TGATAAGTAACTAATACTTT

Downstream 100 bases:

>100_bases
CTGAATGTACGTAAGTCAAAGGGAATATCTTTATATATAAAGATCGGCAATCATACTTTCAATGGCTCAGACAGTAAACA
CTGAAAGGCATTCGAGACTT

Product: AIR synthase related protein domain protein

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKLKDIGEHEFIKRYIKNYVDIKLLDDVFIHEKRGYKVDGFKLSYTFPFMSLYDIGWKAISASTSDIIAKGVKPEFYLIS
LGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDSSGWVDVFVEGEVLCDISNKDIDDGDLLVVGDYIGYTTNVF
ISYINNFNIQILPESLLKVKHPIVRKSLLFFMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIDKNVFNTLK
LRLNLTELDILKYAGEEFLPLLIIDKNSPVKEMLNELQYLAFNPLIIGQVIHEKKAVIYKNTFIKNTGWDNFIGWY

Sequences:

>Translated_316_residues
MKLKDIGEHEFIKRYIKNYVDIKLLDDVFIHEKRGYKVDGFKLSYTFPFMSLYDIGWKAISASTSDIIAKGVKPEFYLIS
LGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDSSGWVDVFVEGEVLCDISNKDIDDGDLLVVGDYIGYTTNVF
ISYINNFNIQILPESLLKVKHPIVRKSLLFFMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIDKNVFNTLK
LRLNLTELDILKYAGEEFLPLLIIDKNSPVKEMLNELQYLAFNPLIIGQVIHEKKAVIYKNTFIKNTGWDNFIGWY
>Mature_316_residues
MKLKDIGEHEFIKRYIKNYVDIKLLDDVFIHEKRGYKVDGFKLSYTFPFMSLYDIGWKAISASTSDIIAKGVKPEFYLIS
LGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDSSGWVDVFVEGEVLCDISNKDIDDGDLLVVGDYIGYTTNVF
ISYINNFNIQILPESLLKVKHPIVRKSLLFFMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIDKNVFNTLK
LRLNLTELDILKYAGEEFLPLLIIDKNSPVKEMLNELQYLAFNPLIIGQVIHEKKAVIYKNTFIKNTGWDNFIGWY

Specific function: Unknown

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36320; Mature: 36320

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKDIGEHEFIKRYIKNYVDIKLLDDVFIHEKRGYKVDGFKLSYTFPFMSLYDIGWKAI
CCCCCCCCHHHHHHHHHHHCCEEEECHHHEECCCCCEECCEEEEEECCHHHHHHCCCCEE
SASTSDIIAKGVKPEFYLISLGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDS
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
SGWVDVFVEGEVLCDISNKDIDDGDLLVVGDYIGYTTNVFISYINNFNIQILPESLLKVK
CCEEEEEECCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHH
HPIVRKSLLFFMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIDKNVFNTLK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHEEEE
LRLNLTELDILKYAGEEFLPLLIIDKNSPVKEMLNELQYLAFNPLIIGQVIHEKKAVIYK
EEEECHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEE
NTFIKNTGWDNFIGWY
EEEEECCCCCCCCCCC
>Mature Secondary Structure
MKLKDIGEHEFIKRYIKNYVDIKLLDDVFIHEKRGYKVDGFKLSYTFPFMSLYDIGWKAI
CCCCCCCCHHHHHHHHHHHCCEEEECHHHEECCCCCEECCEEEEEECCHHHHHHCCCCEE
SASTSDIIAKGVKPEFYLISLGLPPDFDVNKAEELIKGISDAIHYYGGRYIGGDLNDSDS
CCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
SGWVDVFVEGEVLCDISNKDIDDGDLLVVGDYIGYTTNVFISYINNFNIQILPESLLKVK
CCEEEEEECCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHH
HPIVRKSLLFFMKKYCKFIKYSTDISDGLMVSLYKIIDNFDLGINITEIPIDKNVFNTLK
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHEEEE
LRLNLTELDILKYAGEEFLPLLIIDKNSPVKEMLNELQYLAFNPLIIGQVIHEKKAVIYK
EEEECHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEE
NTFIKNTGWDNFIGWY
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]