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The map label for this gene is macB [H]

Identifier: 227827723

GI number: 227827723

Start: 1360702

End: 1361967

Strand: Direct

Name: macB [H]

Synonym: M1425_1454

Alternate gene names: 227827723

Gene position: 1360702-1361967 (Clockwise)

Preceding gene: 227827721

Following gene: 227827724

Centisome position: 52.16

GC content: 37.05

Gene sequence:

>1266_bases
ATGGTGAATACATTAGACATTTTCTGGCTAGCATATAAGGGATTAGTATCTAGGAAAGCTATATCGATTTTAGCTATAAT
ATCAGTTATGATAGGGGTAGCCAGTGTAACTGTACTAGTAGCTTTTACTCAAGGTGTAAGTCAATCTATCTTATCAGTTG
TGGAGTCATTGGGATCTAATACAATTTTAGTTTTACCTAGGGGTGGTGCAAGTTTGACTCAAGCTACTGTAGCAACTATA
GCGAGTTTGCCAGTGATAAAAGCAGTTTATCCAGTAATTAGTGGTTTCGGCGAAATATATGTTGAGGGGCAACCATTAGG
GGTCAGTATAATTGGAATAGATAACTTATCCGCACTTCTTGGTCAAGTACTGCTAGAAAGCGGGTCTGTTTATCCTCCAG
TTTTTTCTCCAGAAGCCGTAATTGGATCAGAAGTGGCAAATCCAGCCCCTGGGGTTTTCTTCTCTCCAGGAAATATAATT
ACTGTTCAAATTTCTAGAGGTAATAGTATAACGTTAGAAGTAGTAGGAGTGTTATCCCCCTCTGGTGCTAATCCTTTATT
TAATTCTGAAACTTCTATATTTTTACCTTTGGGCGAAGCAATGGCTATTCTAAACAGAACTTCATATAGCGAATTAATAG
TTGAGGCTCAATCAGTTAATGATGTTAATAATGTAGTAAACCTTATTGGAGAAATATATGGTACTCAGTTTAGTGTGATT
TCAGTTCAGCAGTTAATTAATACAGTATCTACTATTACGTCTGGGTTTAGTTTTCTATTAATATCAGTTGCGTCAATATC
TCTTTTCGTAGGGGCTGTTGGAATAATGGCGATAATGTTAAGTAGAGTGTATCAGAAGATAAGAGAAATCGGTATAATGA
AAACAGTAGGGCTAACAACTAGAGATATTCTTTTAGTTTTCTTAGCAGAATCTGGGATAATAGGATTAATTGGAGGCATA
GTAGGTGTATTGGTAGGTTTAGTAGGTACTTCATTTATTGATCTTTTATCAGCAATAACGTCTCAATCCGCATCTAGTAG
TTCAGTGAGTACAAACACGGGTGGATCTAGAGGGGGTGGCGGTTTTGGTAGACTTGGTGGAGCATCCGCTTCATCTTCAT
CTTTCTTCACATTTAAACCGATTATTTCGATAGAAGCAATTTTAATAGCATTAGCAGTAGCAATTGTTGTGAGTTTAATA
GCAGGGATTTATCCAGCTTGGAAGGCTTCGAGGCTTACAGCAATTGATGCGATTAGAAGAGATTAA

Upstream 100 bases:

>100_bases
CAACAATTCCCACATATCCCTAATCGGCATATTGGGCATAATAATTGTAATAAGTATAGTCATAGTTTTAGTGATAGTAT
TTTTAAGAAGGAGGTAATTA

Downstream 100 bases:

>100_bases
ATTTTTGTCTTTACATTATATAAACTAGAGCTTATCCTTTTTGGTATGGGCAATTTGAGTGTGATGATGAGAGGGTCCAA
TGATTTGATGATTATCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MVNTLDIFWLAYKGLVSRKAISILAIISVMIGVASVTVLVAFTQGVSQSILSVVESLGSNTILVLPRGGASLTQATVATI
ASLPVIKAVYPVISGFGEIYVEGQPLGVSIIGIDNLSALLGQVLLESGSVYPPVFSPEAVIGSEVANPAPGVFFSPGNII
TVQISRGNSITLEVVGVLSPSGANPLFNSETSIFLPLGEAMAILNRTSYSELIVEAQSVNDVNNVVNLIGEIYGTQFSVI
SVQQLINTVSTITSGFSFLLISVASISLFVGAVGIMAIMLSRVYQKIREIGIMKTVGLTTRDILLVFLAESGIIGLIGGI
VGVLVGLVGTSFIDLLSAITSQSASSSSVSTNTGGSRGGGGFGRLGGASASSSSFFTFKPIISIEAILIALAVAIVVSLI
AGIYPAWKASRLTAIDAIRRD

Sequences:

>Translated_421_residues
MVNTLDIFWLAYKGLVSRKAISILAIISVMIGVASVTVLVAFTQGVSQSILSVVESLGSNTILVLPRGGASLTQATVATI
ASLPVIKAVYPVISGFGEIYVEGQPLGVSIIGIDNLSALLGQVLLESGSVYPPVFSPEAVIGSEVANPAPGVFFSPGNII
TVQISRGNSITLEVVGVLSPSGANPLFNSETSIFLPLGEAMAILNRTSYSELIVEAQSVNDVNNVVNLIGEIYGTQFSVI
SVQQLINTVSTITSGFSFLLISVASISLFVGAVGIMAIMLSRVYQKIREIGIMKTVGLTTRDILLVFLAESGIIGLIGGI
VGVLVGLVGTSFIDLLSAITSQSASSSSVSTNTGGSRGGGGFGRLGGASASSSSFFTFKPIISIEAILIALAVAIVVSLI
AGIYPAWKASRLTAIDAIRRD
>Mature_421_residues
MVNTLDIFWLAYKGLVSRKAISILAIISVMIGVASVTVLVAFTQGVSQSILSVVESLGSNTILVLPRGGASLTQATVATI
ASLPVIKAVYPVISGFGEIYVEGQPLGVSIIGIDNLSALLGQVLLESGSVYPPVFSPEAVIGSEVANPAPGVFFSPGNII
TVQISRGNSITLEVVGVLSPSGANPLFNSETSIFLPLGEAMAILNRTSYSELIVEAQSVNDVNNVVNLIGEIYGTQFSVI
SVQQLINTVSTITSGFSFLLISVASISLFVGAVGIMAIMLSRVYQKIREIGIMKTVGLTTRDILLVFLAESGIIGLIGGI
VGVLVGLVGTSFIDLLSAITSQSASSSSVSTNTGGSRGGGGFGRLGGASASSSSFFTFKPIISIEAILIALAVAIVVSLI
AGIYPAWKASRLTAIDAIRRD

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=430, Percent_Identity=24.1860465116279, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43374; Mature: 43374

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNTLDIFWLAYKGLVSRKAISILAIISVMIGVASVTVLVAFTQGVSQSILSVVESLGSN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TILVLPRGGASLTQATVATIASLPVIKAVYPVISGFGEIYVEGQPLGVSIIGIDNLSALL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHHH
GQVLLESGSVYPPVFSPEAVIGSEVANPAPGVFFSPGNIITVQISRGNSITLEVVGVLSP
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCEEEEEEECCCEEEEEEEEEECC
SGANPLFNSETSIFLPLGEAMAILNRTSYSELIVEAQSVNDVNNVVNLIGEIYGTQFSVI
CCCCCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
SVQQLINTVSTITSGFSFLLISVASISLFVGAVGIMAIMLSRVYQKIREIGIMKTVGLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
RDILLVFLAESGIIGLIGGIVGVLVGLVGTSFIDLLSAITSQSASSSSVSTNTGGSRGGG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GFGRLGGASASSSSFFTFKPIISIEAILIALAVAIVVSLIAGIYPAWKASRLTAIDAIRR
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHC
D
C
>Mature Secondary Structure
MVNTLDIFWLAYKGLVSRKAISILAIISVMIGVASVTVLVAFTQGVSQSILSVVESLGSN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TILVLPRGGASLTQATVATIASLPVIKAVYPVISGFGEIYVEGQPLGVSIIGIDNLSALL
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCHHHHHH
GQVLLESGSVYPPVFSPEAVIGSEVANPAPGVFFSPGNIITVQISRGNSITLEVVGVLSP
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCEEEEEEECCCEEEEEEEEEECC
SGANPLFNSETSIFLPLGEAMAILNRTSYSELIVEAQSVNDVNNVVNLIGEIYGTQFSVI
CCCCCCCCCCCEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
SVQQLINTVSTITSGFSFLLISVASISLFVGAVGIMAIMLSRVYQKIREIGIMKTVGLTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCH
RDILLVFLAESGIIGLIGGIVGVLVGLVGTSFIDLLSAITSQSASSSSVSTNTGGSRGGG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
GFGRLGGASASSSSFFTFKPIISIEAILIALAVAIVVSLIAGIYPAWKASRLTAIDAIRR
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHHHHHHC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA