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The map label for this gene is rpl6p [H]

Identifier: 227827707

GI number: 227827707

Start: 1347928

End: 1348473

Strand: Direct

Name: rpl6p [H]

Synonym: M1425_1436

Alternate gene names: 227827707

Gene position: 1347928-1348473 (Clockwise)

Preceding gene: 227827706

Following gene: 227827708

Centisome position: 51.67

GC content: 34.43

Gene sequence:

>546_bases
ATGCAGATAGTAATTTTAAGGGAAGAGATTGAAATTCCGAGCAATGTAAATGTTGATTTAAAAGACTCAGTAATTAAGAT
GAAAGGACCTAAAGGTGAAGTAGTCAAAGATTTCAGCTTTGCTAGGGGTATACAAATTAGTTTAGATGGAAATAAGATAG
TGTTAGAAACTACATTTGCTAATAGACGAAAAAAGGCGGCCTTCTATAGTATAGTTAGTCATATCAAAAATATGATAACT
GGAGTAACTAAGGGTTATAGGTATTATCTTAAAATTATATATACTCACTTTCCAACATCTGTAAAGGTAGTAGGGAACGA
AGTTCAAATAACTAATCTAATAGGTGAAAAGAATATAAGGAGGGCGCCAATACTACAGGGCGTTAAGGTTACTGTGAAAG
GTGAAGATATAGTTGTGGAGGGCCCGAATTTAGATGCTGTTGCCCAAACTGCAGCAAATATTGAAGCAGCTTCAAAGATA
ACTGGTTTTGATAGACGTATCTTCTCGGATGGAATTTTCATCTATAAAAAAGAGGTGGTTGAATGA

Upstream 100 bases:

>100_bases
TTATTGTTTCGACATCTAAAGGAGTAATGTCTCATAAAGAAGCAGCTAGAATGCGACTAGGAGGAGTAGCATTGGGATAT
GTATATTGAGGTGATTTTTA

Downstream 100 bases:

>100_bases
CCGAAGAAAAAATACAGTCATATAGGAAAAAGATTTATGTAATAAGGCAAAAGCTTAAGGCAAAGAAGCCAAGGTTCTTA
CGTTATGATTCCGACAAGTT

Product: 50S ribosomal protein L6P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MQIVILREEIEIPSNVNVDLKDSVIKMKGPKGEVVKDFSFARGIQISLDGNKIVLETTFANRRKKAAFYSIVSHIKNMIT
GVTKGYRYYLKIIYTHFPTSVKVVGNEVQITNLIGEKNIRRAPILQGVKVTVKGEDIVVEGPNLDAVAQTAANIEAASKI
TGFDRRIFSDGIFIYKKEVVE

Sequences:

>Translated_181_residues
MQIVILREEIEIPSNVNVDLKDSVIKMKGPKGEVVKDFSFARGIQISLDGNKIVLETTFANRRKKAAFYSIVSHIKNMIT
GVTKGYRYYLKIIYTHFPTSVKVVGNEVQITNLIGEKNIRRAPILQGVKVTVKGEDIVVEGPNLDAVAQTAANIEAASKI
TGFDRRIFSDGIFIYKKEVVE
>Mature_181_residues
MQIVILREEIEIPSNVNVDLKDSVIKMKGPKGEVVKDFSFARGIQISLDGNKIVLETTFANRRKKAAFYSIVSHIKNMIT
GVTKGYRYYLKIIYTHFPTSVKVVGNEVQITNLIGEKNIRRAPILQGVKVTVKGEDIVVEGPNLDAVAQTAANIEAASKI
TGFDRRIFSDGIFIYKKEVVE

Specific function: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center [H]

COG id: COG0097

COG function: function code J; Ribosomal protein L6P/L9E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L6P family [H]

Homologues:

Organism=Homo sapiens, GI15431303, Length=189, Percent_Identity=34.3915343915344, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI67944630, Length=189, Percent_Identity=34.3915343915344, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI310133141, Length=165, Percent_Identity=34.5454545454545, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI310118095, Length=137, Percent_Identity=36.4963503649635, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17554746, Length=185, Percent_Identity=34.0540540540541, Blast_Score=113, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324262, Length=184, Percent_Identity=31.5217391304348, Blast_Score=108, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6321291, Length=184, Percent_Identity=30.9782608695652, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24583602, Length=185, Percent_Identity=29.7297297297297, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17137198, Length=185, Percent_Identity=29.7297297297297, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000702
- InterPro:   IPR020040
- InterPro:   IPR002359
- InterPro:   IPR019907 [H]

Pfam domain/function: PF00347 Ribosomal_L6 [H]

EC number: NA

Molecular weight: Translated: 20201; Mature: 20201

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIVILREEIEIPSNVNVDLKDSVIKMKGPKGEVVKDFSFARGIQISLDGNKIVLETTFA
CEEEEEECCCCCCCCCCEEECCCEEEECCCCCCEEECCHHHCCEEEEECCCEEEEEECCC
NRRKKAAFYSIVSHIKNMITGVTKGYRYYLKIIYTHFPTSVKVVGNEVQITNLIGEKNIR
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCEEEEEEECCCCCCC
RAPILQGVKVTVKGEDIVVEGPNLDAVAQTAANIEAASKITGFDRRIFSDGIFIYKKEVV
CCCCCCCEEEEEECCEEEEECCCCCHHHHHHHCHHHHHHHCCCHHHHHHCCEEEEEEECC
E
C
>Mature Secondary Structure
MQIVILREEIEIPSNVNVDLKDSVIKMKGPKGEVVKDFSFARGIQISLDGNKIVLETTFA
CEEEEEECCCCCCCCCCEEECCCEEEECCCCCCEEECCHHHCCEEEEECCCEEEEEECCC
NRRKKAAFYSIVSHIKNMITGVTKGYRYYLKIIYTHFPTSVKVVGNEVQITNLIGEKNIR
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCEEEEEEECCCCCCC
RAPILQGVKVTVKGEDIVVEGPNLDAVAQTAANIEAASKITGFDRRIFSDGIFIYKKEVV
CCCCCCCEEEEEECCEEEEECCCCCHHHHHHHCHHHHHHHCCCHHHHHHCCEEEEEEECC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]