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The map label for this gene is 227827683

Identifier: 227827683

GI number: 227827683

Start: 1329152

End: 1329853

Strand: Direct

Name: 227827683

Synonym: M1425_1412

Alternate gene names: NA

Gene position: 1329152-1329853 (Clockwise)

Preceding gene: 227827682

Following gene: 227827684

Centisome position: 50.95

GC content: 31.05

Gene sequence:

>702_bases
ATGGTAATTAGAATTTATGCTGATGATAGGGAAAAGGCTAGTGGTATACCAGAATTATTAAAGGATTTGGGAATTACAGT
AATATTCTCTCAACTTAGTGTTGCTGATTATGTGATAGGTGAAGATGCTGCAGTAGAGAGGAAGTCGGTAAATGATTTGG
TAAATTCGGTTTTTGACAAGAGGTTTTTTGACCAAATCAGTAGGCTTTCAGAGGTTTATAATTTTCCAATGTTAATTGTT
GAAGGTGATATTAATGAAATTAGGAAAATAACTGAAAAGTGGAGAGCGATAAATAACGCTTTAATTTCTGCCACGATTGA
TTATGATGTTAAAGTATTTTATTCTAGAGATAAAAAAGATACTGCGGAAGTTTTGAAAAAAATAGCAGAGAAGTATCAAT
TTGGCGAAAATGGGAGTAGGAGAATTAATTTACATAATAAGGCTAAACTAGAAAGTATTTCTGATATGCAACTTTATATT
GTAGAATCTTTTCCTAATGTTGGTTCTGTACTTGCTGAAAGGCTACTACTTAAGTTTGGAACTATACAGAATATTTGTAA
TGCGTCTATATCAGAATTGGAAAAAGCATTAGGTAGTAGGAAAAAAGCTGAGGATATTTATAAAATTTTAAGGGCACACT
ATTCTAAAACTAACGCTGATAATGATAGTAAGAAAAGTACCTCTTTATTTGATTTCCTTTAA

Upstream 100 bases:

>100_bases
AGAAGACTTACAAGCTAAAATAAATGAGATGTTATCGAAATATTATCCGCAAGGTGGCCAAACAGGTATAAAAGCTTAAG
CTAAATAACTTATTAGTGTT

Downstream 100 bases:

>100_bases
ATTTTTTAGTCTCTTTTTTAGCATTACCTTTTAATATGGGTCTAGAGAAGTTTAAGTGCAAGAAGTTGGTGATTTCATTT
GCCTAGATATAAGACAGTAG

Product: ERCC4 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MVIRIYADDREKASGIPELLKDLGITVIFSQLSVADYVIGEDAAVERKSVNDLVNSVFDKRFFDQISRLSEVYNFPMLIV
EGDINEIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKYQFGENGSRRINLHNKAKLESISDMQLYI
VESFPNVGSVLAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRAHYSKTNADNDSKKSTSLFDFL

Sequences:

>Translated_233_residues
MVIRIYADDREKASGIPELLKDLGITVIFSQLSVADYVIGEDAAVERKSVNDLVNSVFDKRFFDQISRLSEVYNFPMLIV
EGDINEIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKYQFGENGSRRINLHNKAKLESISDMQLYI
VESFPNVGSVLAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRAHYSKTNADNDSKKSTSLFDFL
>Mature_233_residues
MVIRIYADDREKASGIPELLKDLGITVIFSQLSVADYVIGEDAAVERKSVNDLVNSVFDKRFFDQISRLSEVYNFPMLIV
EGDINEIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKYQFGENGSRRINLHNKAKLESISDMQLYI
VESFPNVGSVLAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRAHYSKTNADNDSKKSTSLFDFL

Specific function: Unknown

COG id: COG1948

COG function: function code L; ERCC4-type nuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI74959747, Length=194, Percent_Identity=26.2886597938144, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR020819
- InterPro:   IPR006166
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR011335
- InterPro:   IPR010994 [H]

Pfam domain/function: PF00270 DEAD; PF02732 ERCC4; PF00271 Helicase_C; PF00633 HHH [H]

EC number: =3.6.4.13 [H]

Molecular weight: Translated: 26533; Mature: 26533

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRIYADDREKASGIPELLKDLGITVIFSQLSVADYVIGEDAAVERKSVNDLVNSVFDK
CEEEEEECCCHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RFFDQISRLSEVYNFPMLIVEGDINEIRKITEKWRAINNALISATIDYDVKVFYSRDKKD
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCH
TAEVLKKIAEKYQFGENGSRRINLHNKAKLESISDMQLYIVESFPNVGSVLAERLLLKFG
HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHH
TIQNICNASISELEKALGSRKKAEDIYKILRAHYSKTNADNDSKKSTSLFDFL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVIRIYADDREKASGIPELLKDLGITVIFSQLSVADYVIGEDAAVERKSVNDLVNSVFDK
CEEEEEECCCHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RFFDQISRLSEVYNFPMLIVEGDINEIRKITEKWRAINNALISATIDYDVKVFYSRDKKD
HHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCH
TAEVLKKIAEKYQFGENGSRRINLHNKAKLESISDMQLYIVESFPNVGSVLAERLLLKFG
HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHH
TIQNICNASISELEKALGSRKKAEDIYKILRAHYSKTNADNDSKKSTSLFDFL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]