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The map label for this gene is cca

Identifier: 227827462

GI number: 227827462

Start: 1114411

End: 1115649

Strand: Direct

Name: cca

Synonym: M1425_1182

Alternate gene names: 227827462

Gene position: 1114411-1115649 (Clockwise)

Preceding gene: 227827461

Following gene: 227827463

Centisome position: 42.72

GC content: 33.58

Gene sequence:

>1239_bases
TTGATAGAGGAGGAAGTACTGAAGATAATAAAACCCACTGAAGAAGACAAAAAAGGAATAGAAAAAGTATTGGAAATCAT
TAGGGAAAGGTTAAATAAATTAGATTTCGAGGTGGAGGGATCATTTAGGAAAGGAACTTGGCTAAGACAAGATACAGATA
TAGACGTCTTCGTATTTTATCCTAAAGATGTTGGAAAAGAATATCTAGAAAGAAACGCTCTAAACGATATTATTAACAGA
ATAAAAGATCTAGATTATACTTTAGCATACGCTGAACATCCGTATGTGATAGTCAATATAAATAACGTAGAAGTAGATAT
AGTCCCAGCCTTGAGAGTGGAAAGCGGAGATAAGGCAATAACTGCAGTTGATAGAACACCATTCCATACGAAATACGTTA
CTTCCCATTTGGACGAAAGAGGAAAAGATGAGGTTAGATTACTTAAAAGGTTCATGAAAGGAATAGGCGTTTACGGGGCT
GAATTGAAAGTACAAGGATTCTCTGGATATGCAACAGAACTCTTAATTATATATTATGGAAATTTTAGAAAAGTTCTAGA
AGAGGCCTCAAAATGGAAGCATCCAATAAAAATAGAATTAACGAAACCAATGAAAATTTTTTCTGAGCCATTAATTATCC
CAGATCCAGTAGACCCTAAAAGAAATGTAACTGCCGCAGTGTCATTAAAAAATATAGCGACATTTTCCATTGCCGCAAAA
TATTATCTAAAAAACCCCTCTATAGAGTTCTTCTTTCCATCAAAAAAAGTAGAGGAAAAAGTTAAGGGAGACGTGCTAAT
TTTAAGGTTAAATTTGGACGAGAAGAGTTCAGAGGATATCGTATGGGGTCAAATAAAGAGAAGTGTAAACAAAATAGAGA
GAGCACTAAAACAATATGGTTTTAGAGTAATCGATGTACAAGCATGGGGAGATACCAATAATATCACTATTGCAGTACAA
CTGGAAAGTAAGAACATTGGACAGTATTATCTCAATATTGGACCACAATACTACTCAGAAACTATAGAAGATTTTATTCA
GAAAAATGATAATATATGGGTTGGAGAAGATGGAAGATTATACTCTATAAAAGAGAGAAAGGAATACGATGCAGAGACAA
TAGCCAAAAAGAATATAGTTCTAAAGGTGAAGTACAATATCGAGAGTTATTGGCTACAAAACACGGAAGATCAACAAATA
ATGAAATTCTTGAGGAAAACTCCAACTTGGTTAAAATAA

Upstream 100 bases:

>100_bases
GTGGATATTGGAACCTTTGAAGTTAATAATGTTGTTCTCTTTAAAAGCACGTTAACTCCAAAAGGTCCAATATATGATAA
ACTGTTTGAAGTGAGTTCAA

Downstream 100 bases:

>100_bases
GCTGTTTTATCTACCCTACTTATTCTAAAGAAGTTGAAGAAGAGCTAAGAAAGGCGGGATTTGATTACGCGTACTCATTT
GGTCAAAAGAACTTAGGGAG

Product: tRNA CCA-pyrophosphorylase

Products: NA

Alternate protein names: tRNA CCA-pyrophosphorylase; tRNA adenylyl-/cytidylyl- transferase; tRNA nucleotidyltransferase; tRNA-NT

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDIDVFVFYPKDVGKEYLERNALNDIINR
IKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDKAITAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGA
ELKVQGFSGYATELLIIYYGNFRKVLEEASKWKHPIKIELTKPMKIFSEPLIIPDPVDPKRNVTAAVSLKNIATFSIAAK
YYLKNPSIEFFFPSKKVEEKVKGDVLILRLNLDEKSSEDIVWGQIKRSVNKIERALKQYGFRVIDVQAWGDTNNITIAVQ
LESKNIGQYYLNIGPQYYSETIEDFIQKNDNIWVGEDGRLYSIKERKEYDAETIAKKNIVLKVKYNIESYWLQNTEDQQI
MKFLRKTPTWLK

Sequences:

>Translated_412_residues
MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDIDVFVFYPKDVGKEYLERNALNDIINR
IKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDKAITAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGA
ELKVQGFSGYATELLIIYYGNFRKVLEEASKWKHPIKIELTKPMKIFSEPLIIPDPVDPKRNVTAAVSLKNIATFSIAAK
YYLKNPSIEFFFPSKKVEEKVKGDVLILRLNLDEKSSEDIVWGQIKRSVNKIERALKQYGFRVIDVQAWGDTNNITIAVQ
LESKNIGQYYLNIGPQYYSETIEDFIQKNDNIWVGEDGRLYSIKERKEYDAETIAKKNIVLKVKYNIESYWLQNTEDQQI
MKFLRKTPTWLK
>Mature_412_residues
MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDIDVFVFYPKDVGKEYLERNALNDIINR
IKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDKAITAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGA
ELKVQGFSGYATELLIIYYGNFRKVLEEASKWKHPIKIELTKPMKIFSEPLIIPDPVDPKRNVTAAVSLKNIATFSIAAK
YYLKNPSIEFFFPSKKVEEKVKGDVLILRLNLDEKSSEDIVWGQIKRSVNKIERALKQYGFRVIDVQAWGDTNNITIAVQ
LESKNIGQYYLNIGPQYYSETIEDFIQKNDNIWVGEDGRLYSIKERKEYDAETIAKKNIVLKVKYNIESYWLQNTEDQQI
MKFLRKTPTWLK

Specific function: Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing

COG id: COG1746

COG function: function code J; tRNA nucleotidyltransferase (CCA-adding enzyme)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCA_SULIA (C3N558)

Other databases:

- EMBL:   CP001401
- RefSeq:   YP_002843178.1
- GeneID:   7814401
- GenomeReviews:   CP001401_GR
- KEGG:   sim:M1627_1246
- OMA:   CEKIISA
- ProtClustDB:   PRK13300
- HAMAP:   MF_01264
- InterPro:   IPR008229
- InterPro:   IPR002934
- InterPro:   IPR011068
- InterPro:   IPR015329
- PIRSF:   PIRSF005335
- TIGRFAMs:   TIGR03671

Pfam domain/function: PF01909 NTP_transf_2; PF09249 tRNA_NucTransf2; SSF55003 PAP_C

EC number: =2.7.7.21; =2.7.7.25

Molecular weight: Translated: 48024; Mature: 48024

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: BINDING 41-41 BINDING 44-44 BINDING 129-129 BINDING 149-149 BINDING 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDIDVFVFY
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCEEEEEEC
PKDVGKEYLERNALNDIINRIKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDKAI
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEEEEEEEECCCCCEE
TAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGAELKVQGFSGYATELLIIYYG
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEC
NFRKVLEEASKWKHPIKIELTKPMKIFSEPLIIPDPVDPKRNVTAAVSLKNIATFSIAAK
CHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEECHHEEEEEEEE
YYLKNPSIEFFFPSKKVEEKVKGDVLILRLNLDEKSSEDIVWGQIKRSVNKIERALKQYG
EEECCCCEEEEECCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
FRVIDVQAWGDTNNITIAVQLESKNIGQYYLNIGPQYYSETIEDFIQKNDNIWVGEDGRL
CEEEEEEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCE
YSIKERKEYDAETIAKKNIVLKVKYNIESYWLQNTEDQQIMKFLRKTPTWLK
EEEHHHHHCCHHHHHCCCEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDIDVFVFY
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCEEEEEEC
PKDVGKEYLERNALNDIINRIKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDKAI
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEEEEEEEECCCCCEE
TAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGAELKVQGFSGYATELLIIYYG
EEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEC
NFRKVLEEASKWKHPIKIELTKPMKIFSEPLIIPDPVDPKRNVTAAVSLKNIATFSIAAK
CHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCEEEEEEECHHEEEEEEEE
YYLKNPSIEFFFPSKKVEEKVKGDVLILRLNLDEKSSEDIVWGQIKRSVNKIERALKQYG
EEECCCCEEEEECCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC
FRVIDVQAWGDTNNITIAVQLESKNIGQYYLNIGPQYYSETIEDFIQKNDNIWVGEDGRL
CEEEEEEECCCCCCEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEECCCCCE
YSIKERKEYDAETIAKKNIVLKVKYNIESYWLQNTEDQQIMKFLRKTPTWLK
EEEHHHHHCCHHHHHCCCEEEEEEECCEEEECCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA