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The map label for this gene is ybeC [H]

Identifier: 227827431

GI number: 227827431

Start: 1088087

End: 1090006

Strand: Direct

Name: ybeC [H]

Synonym: M1425_1150

Alternate gene names: 227827431

Gene position: 1088087-1090006 (Clockwise)

Preceding gene: 227827427

Following gene: 227827432

Centisome position: 41.71

GC content: 37.6

Gene sequence:

>1920_bases
ATGGCTGAGGAAGGCACAAAAGTTTCCGCACAACAAAGTGATAAACTGTTAAGAAAAGAACTAACCCTCTTAGATATGTC
ATTTTTAGGTTTAGGGGCAATAATAGGATCTGGTTGGTTATTCGCATCATTAGCTGCTGCTTCAGTAGCTGGACCATCTG
CAGTACTAGCTTGGATAATTGGAGGAATCCTTATAATGTTTGTAGGATTGGCTTATGCTGAGCTAGGAAGTGCAATACCT
AGAACTGGTGGGATCGTTAGATATCCGCATTATACGCATGGGAGTTACGCTGGTTACATTTTGGGATTTCTTTACTTATT
ATCAGCCATGACAGTACCTGCAATAGAAGCTGAAGCAGCGATAACATACATCAGTTCCATTAACTCGTATATGGGTAGTT
TACTGACCACTACAGCTGATGGGGTAACAATTCTAACGTTACCTGGAATTGGGCTTGCTACCTTGCTGTTAATAGTATTT
TTCTTTATAAATTACTTCGGAATAAAAGTATTAGGGAAGACTAATACTGGAATAACTTTCTGGAAGCTTATAGTCCCAAC
AATTACATTTATACTACTATTAGCTATAGGTTTCAATATAAAGAATTTCACGTCTTATGGAGGTCTATTTCCTTCACTTG
TATCTGGGGCTTCCTCTGGGATTATAGGACCATCAGCGATGCTTTATGCAATACCCAGTACTGGAATAGTCTTCGCATAC
TTGGGATTTAGGCAACCAGTAGAATTTGCTGGAGAAGCTAAAGATCCACAAAGAGATGTACCAAGGGCAATAGTCATAGC
ATTACTCTTGGCTATAGTAATCTATACACTACTTCAAGTTTCATTTATAGGCGCTATAAACTGGCAATATGCAATAAATA
TAAGTAAAGGATATGTTCCAGGGAATTGGAGTGCATTATCATCTGGACCCTGGTCTAGTGGTCCATTCTATGGAGAGATA
ACTACGCTTGGGTCTACCCTAGGTATAGCTGGTTTAATTTATTGGGGATATTTATTACTTGTGGACGCTATAATATCTCC
TAGTGGTACTGGCTTAATCTACATTGGAACTACTACCAGAACTTTTTATGGTATAGCTGCTGACGGTTACTTTCCAAAAT
TCTTCCTCAAATTAAATAAACATAGAATACCCATATGGTCAATCGTAGCTTCACTAATCCTAGGATTCATATTCTTACTA
CCATTCCCAAGCTGGTATCTGTTAGTGGGATTCATTTCTTTAGCAACAGTCTTTACATATATTATGGGAGGTATAGGATT
ACAAACCTTAAGAAAAACCGCGCCAGATCTAAAGAGAAGAGTAAGACTGAGTGGTGCTAGTATCATAGCACCAATAGCTA
CTATCGCTGCAATATTAATCGTATATTGGGCTGGTTTTACAACACTATACTATGTGCTAACTGCATTATTCGTTGGGGTT
CCGCTATTTTGGATGTATTATGCAATAAGAGAATTAAAACTGAACTCAGTTGTTGGAATAGTACTAGGTGTGGCACAACT
CATATTTAATATACTCTTGGCATATTTTGCCTATATTAACATACTAGCTGTACCACCAGGAACGCCAATAAGTGATATAA
TTTCAAGCTTTGTTCTATATTTCTTAGGATTTTTAGGAATATTATTAGTACCTAGCTTAATTGGGTATGCTTTAGTGAAT
GGAAAGGGTAAACAATATATAAGGAGCGGATTCTGGTTAATAGGGCTAATATTAGTAATCTATATAATCAGCTTCTTCGG
AGGATTTGGCCCGTTAGGTACTTCAGCCCCAATACCTTTTCCGTGGGATACTATAGCTGCTGCAATTGTTGGACTAATAT
TCCACTACGCTGCCGTATATAGTGGATTTAGAACTGATGAGATAGAAGAGATAGTTAGAGAACAGTTAGGAGAGAAATAA

Upstream 100 bases:

>100_bases
TTATACATAAAAAGTTAGTACTAATTCTTCGGCAAAGTATAATTAATTATAAGTTGCCGATAATGAAGATTTATATAGTT
TTATTTTTTAAAGTTTAATT

Downstream 100 bases:

>100_bases
TTGTCTCATTTAAAAAGAAACTTTATATTTTTTAGTTAAATCGTCTATATATAGAAAAACTTTTTAGCTGTGAACAAGGT
ATCTAAGTTATGGACTCGAA

Product: amino acid permease-associated region

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 639; Mature: 638

Protein sequence:

>639_residues
MAEEGTKVSAQQSDKLLRKELTLLDMSFLGLGAIIGSGWLFASLAAASVAGPSAVLAWIIGGILIMFVGLAYAELGSAIP
RTGGIVRYPHYTHGSYAGYILGFLYLLSAMTVPAIEAEAAITYISSINSYMGSLLTTTADGVTILTLPGIGLATLLLIVF
FFINYFGIKVLGKTNTGITFWKLIVPTITFILLLAIGFNIKNFTSYGGLFPSLVSGASSGIIGPSAMLYAIPSTGIVFAY
LGFRQPVEFAGEAKDPQRDVPRAIVIALLLAIVIYTLLQVSFIGAINWQYAINISKGYVPGNWSALSSGPWSSGPFYGEI
TTLGSTLGIAGLIYWGYLLLVDAIISPSGTGLIYIGTTTRTFYGIAADGYFPKFFLKLNKHRIPIWSIVASLILGFIFLL
PFPSWYLLVGFISLATVFTYIMGGIGLQTLRKTAPDLKRRVRLSGASIIAPIATIAAILIVYWAGFTTLYYVLTALFVGV
PLFWMYYAIRELKLNSVVGIVLGVAQLIFNILLAYFAYINILAVPPGTPISDIISSFVLYFLGFLGILLVPSLIGYALVN
GKGKQYIRSGFWLIGLILVIYIISFFGGFGPLGTSAPIPFPWDTIAAAIVGLIFHYAAVYSGFRTDEIEEIVREQLGEK

Sequences:

>Translated_639_residues
MAEEGTKVSAQQSDKLLRKELTLLDMSFLGLGAIIGSGWLFASLAAASVAGPSAVLAWIIGGILIMFVGLAYAELGSAIP
RTGGIVRYPHYTHGSYAGYILGFLYLLSAMTVPAIEAEAAITYISSINSYMGSLLTTTADGVTILTLPGIGLATLLLIVF
FFINYFGIKVLGKTNTGITFWKLIVPTITFILLLAIGFNIKNFTSYGGLFPSLVSGASSGIIGPSAMLYAIPSTGIVFAY
LGFRQPVEFAGEAKDPQRDVPRAIVIALLLAIVIYTLLQVSFIGAINWQYAINISKGYVPGNWSALSSGPWSSGPFYGEI
TTLGSTLGIAGLIYWGYLLLVDAIISPSGTGLIYIGTTTRTFYGIAADGYFPKFFLKLNKHRIPIWSIVASLILGFIFLL
PFPSWYLLVGFISLATVFTYIMGGIGLQTLRKTAPDLKRRVRLSGASIIAPIATIAAILIVYWAGFTTLYYVLTALFVGV
PLFWMYYAIRELKLNSVVGIVLGVAQLIFNILLAYFAYINILAVPPGTPISDIISSFVLYFLGFLGILLVPSLIGYALVN
GKGKQYIRSGFWLIGLILVIYIISFFGGFGPLGTSAPIPFPWDTIAAAIVGLIFHYAAVYSGFRTDEIEEIVREQLGEK
>Mature_638_residues
AEEGTKVSAQQSDKLLRKELTLLDMSFLGLGAIIGSGWLFASLAAASVAGPSAVLAWIIGGILIMFVGLAYAELGSAIPR
TGGIVRYPHYTHGSYAGYILGFLYLLSAMTVPAIEAEAAITYISSINSYMGSLLTTTADGVTILTLPGIGLATLLLIVFF
FINYFGIKVLGKTNTGITFWKLIVPTITFILLLAIGFNIKNFTSYGGLFPSLVSGASSGIIGPSAMLYAIPSTGIVFAYL
GFRQPVEFAGEAKDPQRDVPRAIVIALLLAIVIYTLLQVSFIGAINWQYAINISKGYVPGNWSALSSGPWSSGPFYGEIT
TLGSTLGIAGLIYWGYLLLVDAIISPSGTGLIYIGTTTRTFYGIAADGYFPKFFLKLNKHRIPIWSIVASLILGFIFLLP
FPSWYLLVGFISLATVFTYIMGGIGLQTLRKTAPDLKRRVRLSGASIIAPIATIAAILIVYWAGFTTLYYVLTALFVGVP
LFWMYYAIRELKLNSVVGIVLGVAQLIFNILLAYFAYINILAVPPGTPISDIISSFVLYFLGFLGILLVPSLIGYALVNG
KGKQYIRSGFWLIGLILVIYIISFFGGFGPLGTSAPIPFPWDTIAAAIVGLIFHYAAVYSGFRTDEIEEIVREQLGEK

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=525, Percent_Identity=23.2380952380952, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI115648022, Length=525, Percent_Identity=23.2380952380952, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI114326544, Length=286, Percent_Identity=25.1748251748252, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI114326550, Length=286, Percent_Identity=25.1748251748252, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1786602, Length=449, Percent_Identity=25.1670378619154, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081915, Length=466, Percent_Identity=22.7467811158798, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786908, Length=497, Percent_Identity=22.7364185110664, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790653, Length=406, Percent_Identity=22.6600985221675, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=458, Percent_Identity=22.4890829694323, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786302, Length=446, Percent_Identity=21.7488789237668, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788480, Length=392, Percent_Identity=22.9591836734694, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=449, Percent_Identity=23.3853006681514, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533459, Length=436, Percent_Identity=23.6238532110092, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17531343, Length=442, Percent_Identity=23.5294117647059, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=284, Percent_Identity=25.7042253521127, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667468, Length=427, Percent_Identity=25.7611241217799, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21357367, Length=460, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550968, Length=529, Percent_Identity=23.8185255198488, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19921172, Length=529, Percent_Identity=23.8185255198488, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24651635, Length=485, Percent_Identity=22.4742268041237, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651633, Length=485, Percent_Identity=22.4742268041237, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24668806, Length=455, Percent_Identity=21.7582417582418, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356285, Length=455, Percent_Identity=21.7582417582418, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24668802, Length=455, Percent_Identity=21.7582417582418, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331183, Length=282, Percent_Identity=25.886524822695, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17647653, Length=282, Percent_Identity=25.886524822695, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24664379, Length=282, Percent_Identity=25.886524822695, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221512776, Length=283, Percent_Identity=23.6749116607774, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666159, Length=283, Percent_Identity=23.6749116607774, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 68893; Mature: 68762

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEGTKVSAQQSDKLLRKELTLLDMSFLGLGAIIGSGWLFASLAAASVAGPSAVLAWII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGILIMFVGLAYAELGSAIPRTGGIVRYPHYTHGSYAGYILGFLYLLSAMTVPAIEAEAA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
ITYISSINSYMGSLLTTTADGVTILTLPGIGLATLLLIVFFFINYFGIKVLGKTNTGITF
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHH
WKLIVPTITFILLLAIGFNIKNFTSYGGLFPSLVSGASSGIIGPSAMLYAIPSTGIVFAY
HHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCCHHEEECCCCCHHHHH
LGFRQPVEFAGEAKDPQRDVPRAIVIALLLAIVIYTLLQVSFIGAINWQYAINISKGYVP
HCCCCCHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
GNWSALSSGPWSSGPFYGEITTLGSTLGIAGLIYWGYLLLVDAIISPSGTGLIYIGTTTR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TFYGIAADGYFPKFFLKLNKHRIPIWSIVASLILGFIFLLPFPSWYLLVGFISLATVFTY
EEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IMGGIGLQTLRKTAPDLKRRVRLSGASIIAPIATIAAILIVYWAGFTTLYYVLTALFVGV
HHHCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLFWMYYAIRELKLNSVVGIVLGVAQLIFNILLAYFAYINILAVPPGTPISDIISSFVLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
FLGFLGILLVPSLIGYALVNGKGKQYIRSGFWLIGLILVIYIISFFGGFGPLGTSAPIPF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PWDTIAAAIVGLIFHYAAVYSGFRTDEIEEIVREQLGEK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEEGTKVSAQQSDKLLRKELTLLDMSFLGLGAIIGSGWLFASLAAASVAGPSAVLAWII
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GGILIMFVGLAYAELGSAIPRTGGIVRYPHYTHGSYAGYILGFLYLLSAMTVPAIEAEAA
HHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
ITYISSINSYMGSLLTTTADGVTILTLPGIGLATLLLIVFFFINYFGIKVLGKTNTGITF
HHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCEEEEECCCCCHHH
WKLIVPTITFILLLAIGFNIKNFTSYGGLFPSLVSGASSGIIGPSAMLYAIPSTGIVFAY
HHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHCCCCCCCCCCCHHEEECCCCCHHHHH
LGFRQPVEFAGEAKDPQRDVPRAIVIALLLAIVIYTLLQVSFIGAINWQYAINISKGYVP
HCCCCCHHHCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
GNWSALSSGPWSSGPFYGEITTLGSTLGIAGLIYWGYLLLVDAIISPSGTGLIYIGTTTR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
TFYGIAADGYFPKFFLKLNKHRIPIWSIVASLILGFIFLLPFPSWYLLVGFISLATVFTY
EEEEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
IMGGIGLQTLRKTAPDLKRRVRLSGASIIAPIATIAAILIVYWAGFTTLYYVLTALFVGV
HHHCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLFWMYYAIRELKLNSVVGIVLGVAQLIFNILLAYFAYINILAVPPGTPISDIISSFVLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHH
FLGFLGILLVPSLIGYALVNGKGKQYIRSGFWLIGLILVIYIISFFGGFGPLGTSAPIPF
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PWDTIAAAIVGLIFHYAAVYSGFRTDEIEEIVREQLGEK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]