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The map label for this gene is fabG [H]

Identifier: 227826433

GI number: 227826433

Start: 20705

End: 21424

Strand: Direct

Name: fabG [H]

Synonym: M1425_0022

Alternate gene names: 227826433

Gene position: 20705-21424 (Clockwise)

Preceding gene: 227826432

Following gene: 227826434

Centisome position: 0.79

GC content: 39.86

Gene sequence:

>720_bases
ATGGGAAGGTTAGACAATAAGAAAGTAGCTATTATAGGTGTAAGCGAGGGTTTAGGTTACGCCACTGCCTATTTCGCATT
AAAAGAGGGTGCGCAAGTTTGCATAAATTCGAGGAATGAGAACAAGCTAAAGAGAATGAAAGAGACTCTAAGTAAATATG
GTAATATCCATTATGTAGTTGGTGACGTCTCTAGTACTGACAGTGCTAGGAATGTCATAGATAAGTGCGCATCTCTCCTT
AACGGAATAGACCATTTAGTGGTTACTGTTGGTGGGTATGTTGAGGACACAATAGATAATTTTAGCGGATTAGAAGAGAT
GTTAACTAATCACATAAAGATTCCTCTTTATGTTATCAATTCATCCCTAAGGTTTCTTAAGGAAGGCTCTAGTGTAGTCT
TAGTATCATCAATGAGTGGTATTGGCAAGGCTTCTCCTGACCAATTATCTTATGCAGTAGCTAAAGCTGGCTTGGCTAAG
GAGGTCGAGATTTTAGCCTCTGAATTATTAGGGAGGGGAATTAGGGTTAACGGTATTGCTCCAACTACCATAAGCGGAGA
ATTTGAACCTGAAAGAAATTGGAAAAAGCTTAGAAAATTGGGTGATGATATGGCACCTCCAGAGGATTTCGCTAGGATCA
TTATTTGGCTTTTAACTGACGAATCAGATTGGGTAGATGGTGTGGTAATACCAGCTCACGGTGGTGCAAGGCTAAAATAG

Upstream 100 bases:

>100_bases
GTAGAGCATATGTTTGTATAGGCAATACGTGTAGTATGCCAGTAAGTGAAGAGGAAAAGATTAAACAATTACTTAAAACT
AAGCTTTAACATTTTTATGT

Downstream 100 bases:

>100_bases
GTGTCTATAGTGAGTAATGTTGAAAATTTGATTGAAAGCGTAGGAGAATTATGGAATAGGTATGTTAAACACGAATTCGT
ACTTAAGATGAGAGATGGAT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MGRLDNKKVAIIGVSEGLGYATAYFALKEGAQVCINSRNENKLKRMKETLSKYGNIHYVVGDVSSTDSARNVIDKCASLL
NGIDHLVVTVGGYVEDTIDNFSGLEEMLTNHIKIPLYVINSSLRFLKEGSSVVLVSSMSGIGKASPDQLSYAVAKAGLAK
EVEILASELLGRGIRVNGIAPTTISGEFEPERNWKKLRKLGDDMAPPEDFARIIIWLLTDESDWVDGVVIPAHGGARLK

Sequences:

>Translated_239_residues
MGRLDNKKVAIIGVSEGLGYATAYFALKEGAQVCINSRNENKLKRMKETLSKYGNIHYVVGDVSSTDSARNVIDKCASLL
NGIDHLVVTVGGYVEDTIDNFSGLEEMLTNHIKIPLYVINSSLRFLKEGSSVVLVSSMSGIGKASPDQLSYAVAKAGLAK
EVEILASELLGRGIRVNGIAPTTISGEFEPERNWKKLRKLGDDMAPPEDFARIIIWLLTDESDWVDGVVIPAHGGARLK
>Mature_238_residues
GRLDNKKVAIIGVSEGLGYATAYFALKEGAQVCINSRNENKLKRMKETLSKYGNIHYVVGDVSSTDSARNVIDKCASLLN
GIDHLVVTVGGYVEDTIDNFSGLEEMLTNHIKIPLYVINSSLRFLKEGSSVVLVSSMSGIGKASPDQLSYAVAKAGLAKE
VEILASELLGRGIRVNGIAPTTISGEFEPERNWKKLRKLGDDMAPPEDFARIIIWLLTDESDWVDGVVIPAHGGARLK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=27.4900398406374, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=25.6, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=29.3893129770992, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=28.6259541984733, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=28.6792452830189, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=27.0992366412214, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.8195488721804, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.9245283018868, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=30.1470588235294, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=25.2830188679245, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=25.187969924812, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=25.3787878787879, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=26.0377358490566, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=25.2830188679245, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.1632653061224, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=25.2830188679245, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=27.6515151515151, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=25.0936329588015, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=24.6212121212121, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=26.5917602996255, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=25.9842519685039, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=26.8774703557312, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25936; Mature: 25805

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLDNKKVAIIGVSEGLGYATAYFALKEGAQVCINSRNENKLKRMKETLSKYGNIHYVV
CCCCCCCEEEEEEECCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHHHHCCEEEEE
GDVSSTDSARNVIDKCASLLNGIDHLVVTVGGYVEDTIDNFSGLEEMLTNHIKIPLYVIN
ECCCCCHHHHHHHHHHHHHHHHHHHEEHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEC
SSLRFLKEGSSVVLVSSMSGIGKASPDQLSYAVAKAGLAKEVEILASELLGRGIRVNGIA
CHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCC
PTTISGEFEPERNWKKLRKLGDDMAPPEDFARIIIWLLTDESDWVDGVVIPAHGGARLK
CCEECCCCCCCHHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
GRLDNKKVAIIGVSEGLGYATAYFALKEGAQVCINSRNENKLKRMKETLSKYGNIHYVV
CCCCCCEEEEEEECCCCCHHHHHHHHHHCHHEEECCCCHHHHHHHHHHHHHHCCEEEEE
GDVSSTDSARNVIDKCASLLNGIDHLVVTVGGYVEDTIDNFSGLEEMLTNHIKIPLYVIN
ECCCCCHHHHHHHHHHHHHHHHHHHEEHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEEC
SSLRFLKEGSSVVLVSSMSGIGKASPDQLSYAVAKAGLAKEVEILASELLGRGIRVNGIA
CHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCC
PTTISGEFEPERNWKKLRKLGDDMAPPEDFARIIIWLLTDESDWVDGVVIPAHGGARLK
CCEECCCCCCCHHHHHHHHHCCCCCCHHHHHHEEEEEEECCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377 [H]