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The map label for this gene is kinD [H]

Identifier: 227815819

GI number: 227815819

Start: 2945166

End: 2946608

Strand: Direct

Name: kinD [H]

Synonym: BAMEG_3243

Alternate gene names: 227815819

Gene position: 2945166-2946608 (Clockwise)

Preceding gene: 227815814

Following gene: 227815821

Centisome position: 56.31

GC content: 34.72

Gene sequence:

>1443_bases
ATGATCGGTATTGGTGCTACATTTTATTCATATCATTCGTATAAAATGAAACAGGAAAACAAACGAATTGCTCATACGGT
GCTCTTTTTATATAGAGACTATTTAGATCACCATCTTGGCGAAGCAATTTCTGCCTTAGAAATGCTCTCAAAGGTCGTAG
GAACCGAGACTGGAAATATTAATGGAATGAAAGAAATTGTACATGATACTGATGGAAACGATGCACGTTTTTCTGGTCTA
TATTACACTACACCAGAAGGTATCATTACAATTGCATCAGAAGGCGACCGGCCACCTGTTGATGTCTCAGATCGTAAATA
TATTCAAAACGCATTACAAACTAAGAAAACAACTGTATCATCCGTCATTACAGATCGTGTTCTTGGCCATCAAGCTATTA
TGATTGCTTCTCCCATTTTCAATAAACAGAAGGAGCTCTCAGGCTTATTGTTAGCAAGTTTACGCTTTGACTACATTTCA
TCATCCTTAAATGCCATTAAACCGCAATACCATTTTGAAGTAACTGATAAGTATGATGTAGTTTTTCTAACCGATGATAA
TAATGAAACAAGTGATGCGCATTCTAATATGCTTACTACTCCACTCCAAAGATTAGATTGGAAGGTCTCTGTTTCTCCTT
TACCTATTCATCAAAAAACTTTAAATCAGTGGGTTGCCGTAGAATGTATAGCTACTTTATTTTTAATGTCAATTTTATTT
TTACTCGCTCAATATATGTTGTTAAAACGACAAACAAAACTGGAAAGACAACAAAATGAACTACAAAAAATTGAATTAGT
TGGAACTTTTGCAGCTAGTACAGCCCACGAAATCCGTAATCCACTTACCGGAATTAAAGGGCTCGTCGCTCTATTAAAAG
AGAAATATAAAGATGAACAAGATCAGTTCTATTTTTCCATCATCGAACAAGAGATAAAACGAATTAATGAAATTGTAAGT
GAATTTCTTATTCTTGGAAAGCCAACTGCAACCATTGAACAAACATATGATGTGAGAACCATTCTAAATGAGGTAGCATT
AATTATTCAATCTGAGGCGAATCTACATAACATTGTATTCCATTTACATTTGCCAGACCACCCTGTTCATATCCGGTGCT
CAAAAGACCATATGAAACAAGTGGTTTTAAACATTACAAAAAATGCAATTGAAGCTATGACTTCTGGTGATACACTAACT
ATTTCCGTAACAAGCAATGAAACACACGCACAATTGCAAATTATAGATACTGGAAAAGGGATTCCAAAACATATTCAAAA
ACACCTCTTTCATCCGTTCTTTACTAATAAAGATACTGGAACAGGTCTTGGACTTGTCATATGTAAACGAATTGTAGAGA
TGTATAATGGGCACCTTTTTATTGACAGTATAGAAAACGAAGGAACGACAGTTCATGCCGAAATTCCATTACACATAGTA
TAA

Upstream 100 bases:

>100_bases
AACATAGTTTATATATAATGATAATAAAAAAGAAGGAGTTCCAAATTTGAAATTCAAATTCCACAACATAGTTTTATATA
TATTGCTTGTTATCCTACCA

Downstream 100 bases:

>100_bases
TTATCCTTATCCCAAAAGGGTAATTATACTTATTTCATAAAACCAGCCACAAGCATTCGCCAAAAATTACTTGATTTCCC
TTCATACCCAATTTGAAAAA

Product: sensor histidine kinase KinD

Products: NA

Alternate protein names: Sensor histidine kinase D [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MIGIGATFYSYHSYKMKQENKRIAHTVLFLYRDYLDHHLGEAISALEMLSKVVGTETGNINGMKEIVHDTDGNDARFSGL
YYTTPEGIITIASEGDRPPVDVSDRKYIQNALQTKKTTVSSVITDRVLGHQAIMIASPIFNKQKELSGLLLASLRFDYIS
SSLNAIKPQYHFEVTDKYDVVFLTDDNNETSDAHSNMLTTPLQRLDWKVSVSPLPIHQKTLNQWVAVECIATLFLMSILF
LLAQYMLLKRQTKLERQQNELQKIELVGTFAASTAHEIRNPLTGIKGLVALLKEKYKDEQDQFYFSIIEQEIKRINEIVS
EFLILGKPTATIEQTYDVRTILNEVALIIQSEANLHNIVFHLHLPDHPVHIRCSKDHMKQVVLNITKNAIEAMTSGDTLT
ISVTSNETHAQLQIIDTGKGIPKHIQKHLFHPFFTNKDTGTGLGLVICKRIVEMYNGHLFIDSIENEGTTVHAEIPLHIV

Sequences:

>Translated_480_residues
MIGIGATFYSYHSYKMKQENKRIAHTVLFLYRDYLDHHLGEAISALEMLSKVVGTETGNINGMKEIVHDTDGNDARFSGL
YYTTPEGIITIASEGDRPPVDVSDRKYIQNALQTKKTTVSSVITDRVLGHQAIMIASPIFNKQKELSGLLLASLRFDYIS
SSLNAIKPQYHFEVTDKYDVVFLTDDNNETSDAHSNMLTTPLQRLDWKVSVSPLPIHQKTLNQWVAVECIATLFLMSILF
LLAQYMLLKRQTKLERQQNELQKIELVGTFAASTAHEIRNPLTGIKGLVALLKEKYKDEQDQFYFSIIEQEIKRINEIVS
EFLILGKPTATIEQTYDVRTILNEVALIIQSEANLHNIVFHLHLPDHPVHIRCSKDHMKQVVLNITKNAIEAMTSGDTLT
ISVTSNETHAQLQIIDTGKGIPKHIQKHLFHPFFTNKDTGTGLGLVICKRIVEMYNGHLFIDSIENEGTTVHAEIPLHIV
>Mature_480_residues
MIGIGATFYSYHSYKMKQENKRIAHTVLFLYRDYLDHHLGEAISALEMLSKVVGTETGNINGMKEIVHDTDGNDARFSGL
YYTTPEGIITIASEGDRPPVDVSDRKYIQNALQTKKTTVSSVITDRVLGHQAIMIASPIFNKQKELSGLLLASLRFDYIS
SSLNAIKPQYHFEVTDKYDVVFLTDDNNETSDAHSNMLTTPLQRLDWKVSVSPLPIHQKTLNQWVAVECIATLFLMSILF
LLAQYMLLKRQTKLERQQNELQKIELVGTFAASTAHEIRNPLTGIKGLVALLKEKYKDEQDQFYFSIIEQEIKRINEIVS
EFLILGKPTATIEQTYDVRTILNEVALIIQSEANLHNIVFHLHLPDHPVHIRCSKDHMKQVVLNITKNAIEAMTSGDTLT
ISVTSNETHAQLQIIDTGKGIPKHIQKHLFHPFFTNKDTGTGLGLVICKRIVEMYNGHLFIDSIENEGTTVHAEIPLHIV

Specific function: Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=33.8582677165354, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788549, Length=232, Percent_Identity=29.3103448275862, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=27.6785714285714, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=215, Percent_Identity=26.9767441860465, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789808, Length=213, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=24.390243902439, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=24.5535714285714, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=24.6575342465753, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=20.9677419354839, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=23.9316239316239, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54289; Mature: 54289

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIGATFYSYHSYKMKQENKRIAHTVLFLYRDYLDHHLGEAISALEMLSKVVGTETGNI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NGMKEIVHDTDGNDARFSGLYYTTPEGIITIASEGDRPPVDVSDRKYIQNALQTKKTTVS
CHHHHHHCCCCCCCCEECCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
SVITDRVLGHQAIMIASPIFNKQKELSGLLLASLRFDYISSSLNAIKPQYHFEVTDKYDV
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEE
VFLTDDNNETSDAHSNMLTTPLQRLDWKVSVSPLPIHQKTLNQWVAVECIATLFLMSILF
EEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLAQYMLLKRQTKLERQQNELQKIELVGTFAASTAHEIRNPLTGIKGLVALLKEKYKDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DQFYFSIIEQEIKRINEIVSEFLILGKPTATIEQTYDVRTILNEVALIIQSEANLHNIVF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HLHLPDHPVHIRCSKDHMKQVVLNITKNAIEAMTSGDTLTISVTSNETHAQLQIIDTGKG
EEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCC
IPKHIQKHLFHPFFTNKDTGTGLGLVICKRIVEMYNGHLFIDSIENEGTTVHAEIPLHIV
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCEEEC
>Mature Secondary Structure
MIGIGATFYSYHSYKMKQENKRIAHTVLFLYRDYLDHHLGEAISALEMLSKVVGTETGNI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NGMKEIVHDTDGNDARFSGLYYTTPEGIITIASEGDRPPVDVSDRKYIQNALQTKKTTVS
CHHHHHHCCCCCCCCEECCEEEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
SVITDRVLGHQAIMIASPIFNKQKELSGLLLASLRFDYISSSLNAIKPQYHFEVTDKYDV
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEE
VFLTDDNNETSDAHSNMLTTPLQRLDWKVSVSPLPIHQKTLNQWVAVECIATLFLMSILF
EEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLAQYMLLKRQTKLERQQNELQKIELVGTFAASTAHEIRNPLTGIKGLVALLKEKYKDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DQFYFSIIEQEIKRINEIVSEFLILGKPTATIEQTYDVRTILNEVALIIQSEANLHNIVF
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HLHLPDHPVHIRCSKDHMKQVVLNITKNAIEAMTSGDTLTISVTSNETHAQLQIIDTGKG
EEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEECCCC
IPKHIQKHLFHPFFTNKDTGTGLGLVICKRIVEMYNGHLFIDSIENEGTTVHAEIPLHIV
CHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]