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The map label for this gene is flhA [H]

Identifier: 227082196

GI number: 227082196

Start: 2161351

End: 2163444

Strand: Reverse

Name: flhA [H]

Synonym: VCM66_1993

Alternate gene names: 227082196

Gene position: 2163444-2161351 (Counterclockwise)

Preceding gene: 227082199

Following gene: 227082195

Centisome position: 74.79

GC content: 49.95

Gene sequence:

>2094_bases
ATGAAATTTACAATGCCATTTGCGGACAAATTGCCTTCAATTCCACAGCGTAGCATGCCTGCGATCGGTGCTCCGGTCAT
GGTATTGGCCGCATTGGCGATGGTTGTCCTCCCAATGCCAGCCTTTCTGCTCGACTTGTTCTTCACTTTCAACATCGCTC
TGTCGTTAGTGGTGCTTCTAGTCACCGTCTATACCCGTAGGCCATTAGATTTTGCGGCGTTTCCAACGGTACTGCTGATC
GCGACCTTGCTACGCTTGGCACTGAACGTTGCGTCAACGCGAGTCGTTTTGCTGTACGGTCATGAAGGTCCAGGTGCGGC
GGGTAACGTTATCGAAGCGTTTGGTAACGTGGTGATTGGTGGGAATTACGCGGTCGGTTTGGTGGTGTTCCTTATCCTGA
TGATCATCAACTTTATGGTGGTAACCAAAGGTGCGGGACGAATTTCCGAAGTTAGTGCCCGCTTTACCTTAGATGCCTTG
CCCGGCAAGCAGATGGCGATTGATGCTGACTTAAACGCGGGCTTGATTGACCAAGAACAAGCACGTGTGCGCCGTTTTGA
AGTCACCAAAGAAGCGGACTTCTACGGTTCGATGGATGGTGCGTCAAAATTTGTAAAGGGTGATGCGATCGCCGGTATTT
TGATTCTTTTTATCAACATCATCGGTGGCCTGAGTATCGGAATGATCCAGTATGATTTGGGTTTCAAAGAAGCGATCGAA
ATCTACACCCTGTTGACCATCGGTGATGGCTTAGTTGCTCAAATTCCATCACTGCTCTTATCGATTGGCGCTGCGATTAT
GGTTACGCGTCAAAATACCGATGAGGACATGGGACAGCAGGTTATCTTCCAACTGTTTGATAACCCGAAAGCTCTCACCA
TTACCGCAGGTATCCTGTTTGTTATGGGGATTGTCCCCGGGATGCCACATTTTGCCTTCCTGTTTTTAGCGCTACTGGCC
AGTGGTGCGGCGTATTGGCTGCACCGTAAACAGAAAACCAAAGCGGAGAATAAAAATCTGCCCGCCAAGAGCGATGTGGA
AACCCCGACCCAACGTGAACTGTCATGGGATGATGTACAGCCGGTTGACGTGATTGGTTTGGAAGTGGGTTATCGCTTGA
TCCCCTTGGTGGATAAAGATCAAGGTGGCGAGCTGCTTGAACGCGTTAAAGGGGTGCGTAAAAAACTGTCGCAGGACTTT
GGTTTCCTTATTCCACCGGTACATATTCGTGACAACCTAGAATTAACGCCCAATAGTTACCGCATCACCTTGATGGGCGT
AGCCGTGGGTGAAGCAGAAATTCGGCCAGATCAAGAGTTGGCGATTAACCCGGGACAAGTGTACGGCATGATTGATGGTG
AGCGCACTCGCGACCCGGCTTTTGGTCTGGATGCAGTGTGGATACGGGAAGATCAGCGTGAGCATGCGCAGGCTTTGGGC
TATACCGTGGTCGATTCTTCCACTGTGCTCGCCACTCATCTTAGTCAACTGCTCACCAACAATGCGGCACAGCTGATTGG
CCATGAAGAAGTTCAGAATCTGCTGGAAATGCTCTCGCGCTCCGCGCCCAAACTGGTGGAAAACTTTGTACCAGATCAGC
TTTCGCTGGGGGTCGTGGTCAAAGTTCTACAGAATTTGCTGCATGAAGCGATCCCGATCCGCGATATTCGCACCATAGTG
CAAACCCTTTCGGAATACGCGAGTAAGAGTCAAGAACCCGACATTTTAACTGCAGCGGTGCGCATCTCACTCAAACGACT
TATTGTCCAAGAAATCAATGGGGTAGAGCCTGAATTGCCTGTAATTACCTTAATTCCGGAGCTGGAACAAATTTTGCATC
AAACTATGCAAGCTTCGGGTGGTGAATCAGCAGGTATTGAGCCGGGACTGGCGGAAAGACTGCAAATGGCGCTAAGCCAC
GCCACTCAAGAGCAGGAGTTGAAAGGGGAACCCGCAGTATTGCTGACATCTGGCGTATTGCGTTCAACGCTAGCGAAGTT
TGTGAAAAACACCATTCCCAACCTTCGCGTGCTCTCCTATCAGGAGATCCCCGATGAGAAACAAATTCGAATTGTGCAGG
CCGTGGGTAATTAA

Upstream 100 bases:

>100_bases
CCTACGGCGGCCGAACTGCAACTCCAAGTCGTTTGGTTATAGCATCGCTACGGCGCAGCCTTGATGTTCCGATTAACCCT
TCAGTGACAGCCAGAAATTT

Downstream 100 bases:

>100_bases
TCGTCCGCACGTTTTTTAAAGACGGAAATCTGCTTTGAAAATAAAACGATTTTTTGCCAAGGATATGAAAACTGCGCTGC
TTCAGGTCAAAGAAGAGCTG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MKFTMPFADKLPSIPQRSMPAIGAPVMVLAALAMVVLPMPAFLLDLFFTFNIALSLVVLLVTVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLYGHEGPGAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARVRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMIQYDLGFKEAIE
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGQQVIFQLFDNPKALTITAGILFVMGIVPGMPHFAFLFLALLA
SGAAYWLHRKQKTKAENKNLPAKSDVETPTQRELSWDDVQPVDVIGLEVGYRLIPLVDKDQGGELLERVKGVRKKLSQDF
GFLIPPVHIRDNLELTPNSYRITLMGVAVGEAEIRPDQELAINPGQVYGMIDGERTRDPAFGLDAVWIREDQREHAQALG
YTVVDSSTVLATHLSQLLTNNAAQLIGHEEVQNLLEMLSRSAPKLVENFVPDQLSLGVVVKVLQNLLHEAIPIRDIRTIV
QTLSEYASKSQEPDILTAAVRISLKRLIVQEINGVEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQMALSH
ATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN

Sequences:

>Translated_697_residues
MKFTMPFADKLPSIPQRSMPAIGAPVMVLAALAMVVLPMPAFLLDLFFTFNIALSLVVLLVTVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLYGHEGPGAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARVRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMIQYDLGFKEAIE
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGQQVIFQLFDNPKALTITAGILFVMGIVPGMPHFAFLFLALLA
SGAAYWLHRKQKTKAENKNLPAKSDVETPTQRELSWDDVQPVDVIGLEVGYRLIPLVDKDQGGELLERVKGVRKKLSQDF
GFLIPPVHIRDNLELTPNSYRITLMGVAVGEAEIRPDQELAINPGQVYGMIDGERTRDPAFGLDAVWIREDQREHAQALG
YTVVDSSTVLATHLSQLLTNNAAQLIGHEEVQNLLEMLSRSAPKLVENFVPDQLSLGVVVKVLQNLLHEAIPIRDIRTIV
QTLSEYASKSQEPDILTAAVRISLKRLIVQEINGVEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQMALSH
ATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
>Mature_697_residues
MKFTMPFADKLPSIPQRSMPAIGAPVMVLAALAMVVLPMPAFLLDLFFTFNIALSLVVLLVTVYTRRPLDFAAFPTVLLI
ATLLRLALNVASTRVVLLYGHEGPGAAGNVIEAFGNVVIGGNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDAL
PGKQMAIDADLNAGLIDQEQARVRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMIQYDLGFKEAIE
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGQQVIFQLFDNPKALTITAGILFVMGIVPGMPHFAFLFLALLA
SGAAYWLHRKQKTKAENKNLPAKSDVETPTQRELSWDDVQPVDVIGLEVGYRLIPLVDKDQGGELLERVKGVRKKLSQDF
GFLIPPVHIRDNLELTPNSYRITLMGVAVGEAEIRPDQELAINPGQVYGMIDGERTRDPAFGLDAVWIREDQREHAQALG
YTVVDSSTVLATHLSQLLTNNAAQLIGHEEVQNLLEMLSRSAPKLVENFVPDQLSLGVVVKVLQNLLHEAIPIRDIRTIV
QTLSEYASKSQEPDILTAAVRISLKRLIVQEINGVEPELPVITLIPELEQILHQTMQASGGESAGIEPGLAERLQMALSH
ATQEQELKGEPAVLLTSGVLRSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=677, Percent_Identity=54.0620384047267, Blast_Score=709, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76048; Mature: 76048

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTMPFADKLPSIPQRSMPAIGAPVMVLAALAMVVLPMPAFLLDLFFTFNIALSLVVLL
CCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VTVYTRRPLDFAAFPTVLLIATLLRLALNVASTRVVLLYGHEGPGAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCEEEC
GNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHH
ARVRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMIQYDLGFKEAIE
HHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEHEEECCCHHHHHH
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGQQVIFQLFDNPKALTITAGILF
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
VMGIVPGMPHFAFLFLALLASGAAYWLHRKQKTKAENKNLPAKSDVETPTQRELSWDDVQ
HHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPLVDKDQGGELLERVKGVRKKLSQDFGFLIPPVHIRDNLELTPNSY
CHHEEEHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEECCCCE
RITLMGVAVGEAEIRPDQELAINPGQVYGMIDGERTRDPAFGLDAVWIREDQREHAQALG
EEEEEEEEECCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHCC
YTVVDSSTVLATHLSQLLTNNAAQLIGHEEVQNLLEMLSRSAPKLVENFVPDQLSLGVVV
EEEECCCHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
KVLQNLLHEAIPIRDIRTIVQTLSEYASKSQEPDILTAAVRISLKRLIVQEINGVEPELP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGESAGIEPGLAERLQMALSHATQEQELKGEPAVLLTSGVL
EEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCEEEHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC
>Mature Secondary Structure
MKFTMPFADKLPSIPQRSMPAIGAPVMVLAALAMVVLPMPAFLLDLFFTFNIALSLVVLL
CCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VTVYTRRPLDFAAFPTVLLIATLLRLALNVASTRVVLLYGHEGPGAAGNVIEAFGNVVIG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCEEEC
GNYAVGLVVFLILMIINFMVVTKGAGRISEVSARFTLDALPGKQMAIDADLNAGLIDQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHH
ARVRRFEVTKEADFYGSMDGASKFVKGDAIAGILILFINIIGGLSIGMIQYDLGFKEAIE
HHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCCEEHEEECCCHHHHHH
IYTLLTIGDGLVAQIPSLLLSIGAAIMVTRQNTDEDMGQQVIFQLFDNPKALTITAGILF
HHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHH
VMGIVPGMPHFAFLFLALLASGAAYWLHRKQKTKAENKNLPAKSDVETPTQRELSWDDVQ
HHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
PVDVIGLEVGYRLIPLVDKDQGGELLERVKGVRKKLSQDFGFLIPPVHIRDNLELTPNSY
CHHEEEHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEECCCCE
RITLMGVAVGEAEIRPDQELAINPGQVYGMIDGERTRDPAFGLDAVWIREDQREHAQALG
EEEEEEEEECCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHCC
YTVVDSSTVLATHLSQLLTNNAAQLIGHEEVQNLLEMLSRSAPKLVENFVPDQLSLGVVV
EEEECCCHHHHHHHHHHHHCCHHHHHCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
KVLQNLLHEAIPIRDIRTIVQTLSEYASKSQEPDILTAAVRISLKRLIVQEINGVEPELP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VITLIPELEQILHQTMQASGGESAGIEPGLAERLQMALSHATQEQELKGEPAVLLTSGVL
EEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCEEEHHHHH
RSTLAKFVKNTIPNLRVLSYQEIPDEKQIRIVQAVGN
HHHHHHHHHHCCCCCEEEEHHCCCCHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]