Click here to switch to the map view.

The map label for this gene is minC

Identifier: 227082088

GI number: 227082088

Start: 2048135

End: 2048797

Strand: Direct

Name: minC

Synonym: VCM66_1883

Alternate gene names: 227082088

Gene position: 2048135-2048797 (Clockwise)

Preceding gene: 227082087

Following gene: 227082089

Centisome position: 70.81

GC content: 48.57

Gene sequence:

>663_bases
ATGTCGAAAAACCCTGACCTGAAAGGTAGTAGTTTTACTTTGTCGGTATTACACCTTTCTGACAACCAAATTGCGCATAC
TGTTCAATTTCTTCAAGAAAAGATCGCGCAAGCCCCGGCCTTTTTTGCCAATGCGCCAGTGGTGATCAATGTGGCGAAAG
TCGAGGGCGATATTGATTATCCTGCGTTAAAACAAGGGATCAGCCAAGCGGGTTTAATCCCCGTCGGTGTCACAGGATGT
AAAGACAAACGTAGCCAAAACCTTGCCGTCGAAGCCGGTTTTGCAGTAATGACCGCCACAAACTCCCCAGCCCAAGCCCC
AGCGCAAATGGCTCCGACCAAAGTGATTCGTACCCCAGTACGTTCGGGTCAACAGATTTATGCCAAAGACGGCGATCTGG
TGATCTTAAGTCACGTCAGTGCGGGGGCTGAAGTGATCGCCGATGGTTCAATCCATATTTATGGCACGTTACGTGGCCGT
GCGATTGCCGGAGCGAGTGGTCAACGAGAAGCACGAATTATTTGTCATGATTTGCAAGCGGAATTGATTTCCATCGCTGG
CCGCTATTGGTTAAGTGATCAAATTGAAAGTCAGTTCTGGCAACAGAGGGTGATGCTCAGTATGACTGACGAATCGCTCT
ATCTCGAAACGCTCACGATTTAA

Upstream 100 bases:

>100_bases
GAGAACTTGCTGTGCTTTGGCGCTGAATATAACATGACAGCCCTGTTCTCAGCCAATGCTCTCTCCGTAAGGCATAGAGT
TTATTGAGGTCAACGTTACC

Downstream 100 bases:

>100_bases
GATTGAAAGGAAAAAATAACATGTCGCGCATTATTGTCGTCACGTCAGGAAAAGGCGGGGTTGGCAAAACCACCTCCAGT
GCTGCAATTGCTTCAGGTCT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSKNPDLKGSSFTLSVLHLSDNQIAHTVQFLQEKIAQAPAFFANAPVVINVAKVEGDIDYPALKQGISQAGLIPVGVTGC
KDKRSQNLAVEAGFAVMTATNSPAQAPAQMAPTKVIRTPVRSGQQIYAKDGDLVILSHVSAGAEVIADGSIHIYGTLRGR
AIAGASGQREARIICHDLQAELISIAGRYWLSDQIESQFWQQRVMLSMTDESLYLETLTI

Sequences:

>Translated_220_residues
MSKNPDLKGSSFTLSVLHLSDNQIAHTVQFLQEKIAQAPAFFANAPVVINVAKVEGDIDYPALKQGISQAGLIPVGVTGC
KDKRSQNLAVEAGFAVMTATNSPAQAPAQMAPTKVIRTPVRSGQQIYAKDGDLVILSHVSAGAEVIADGSIHIYGTLRGR
AIAGASGQREARIICHDLQAELISIAGRYWLSDQIESQFWQQRVMLSMTDESLYLETLTI
>Mature_219_residues
SKNPDLKGSSFTLSVLHLSDNQIAHTVQFLQEKIAQAPAFFANAPVVINVAKVEGDIDYPALKQGISQAGLIPVGVTGCK
DKRSQNLAVEAGFAVMTATNSPAQAPAQMAPTKVIRTPVRSGQQIYAKDGDLVILSHVSAGAEVIADGSIHIYGTLRGRA
IAGASGQREARIICHDLQAELISIAGRYWLSDQIESQFWQQRVMLSMTDESLYLETLTI

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=231, Percent_Identity=48.0519480519481, Blast_Score=218, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_VIBC3 (A5F6U9)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F6U9
- SMR:   A5F6U9
- STRING:   A5F6U9
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1545
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   IFCTHLA
- ProtClustDB:   PRK04804
- BioCyc:   VCHO345073:VC0395_A1545-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 23646; Mature: 23515

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNPDLKGSSFTLSVLHLSDNQIAHTVQFLQEKIAQAPAFFANAPVVINVAKVEGDIDY
CCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCCCC
PALKQGISQAGLIPVGVTGCKDKRSQNLAVEAGFAVMTATNSPAQAPAQMAPTKVIRTPV
HHHHHCHHHCCCEEEECCCCCCCCCCCEEEEECEEEEEECCCCCCCCHHHCCHHHHHHHH
RSGQQIYAKDGDLVILSHVSAGAEVIADGSIHIYGTLRGRAIAGASGQREARIICHDLQA
CCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCEEEECCCCCCCCEEEEHHHHH
ELISIAGRYWLSDQIESQFWQQRVMLSMTDESLYLETLTI
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECC
>Mature Secondary Structure 
SKNPDLKGSSFTLSVLHLSDNQIAHTVQFLQEKIAQAPAFFANAPVVINVAKVEGDIDY
CCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEEEEECCCCCC
PALKQGISQAGLIPVGVTGCKDKRSQNLAVEAGFAVMTATNSPAQAPAQMAPTKVIRTPV
HHHHHCHHHCCCEEEECCCCCCCCCCCEEEEECEEEEEECCCCCCCCHHHCCHHHHHHHH
RSGQQIYAKDGDLVILSHVSAGAEVIADGSIHIYGTLRGRAIAGASGQREARIICHDLQA
CCCCEEEECCCCEEEEEECCCCCEEEECCCEEEEEEECCEEEECCCCCCCCEEEEHHHHH
ELISIAGRYWLSDQIESQFWQQRVMLSMTDESLYLETLTI
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA