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The map label for this gene is sdcS [H]

Identifier: 227081485

GI number: 227081485

Start: 1354465

End: 1355928

Strand: Direct

Name: sdcS [H]

Synonym: VCM66_1269

Alternate gene names: 227081485

Gene position: 1354465-1355928 (Clockwise)

Preceding gene: 227081481

Following gene: 227081486

Centisome position: 46.83

GC content: 47.27

Gene sequence:

>1464_bases
GTGCCAGCTCCTCGCCAAACACATAATCGATTCTCAGGAAGAGTGAATATGATGCGCCCTTATCTTAAATATATTATTCC
GTTGCTGATCCCCATGTTGGTCTTGATGCTTCCTGCCACCGCATTCCCTTTCGAAGGGCTGACTGTCATACAACAAAGGG
TCATCGCGATTTTCCTATTAGCGGCGCTCTTGTGGGTATTTGAACCGATTCCTATCTATTCCACGTCGGTGGTGATCATT
GTGCTCGAAGTGCTGATGCTTTCCGATAAAGGCTTCATTTTGTTTCGGTTGGGTGAGGGGACAAGCGAATTTGGTGCTTT
GCTGAAATCAACTGAAATCATGGCAACCTTTGCCAACCCTATTATCATGCTGTTTTTAGGCGGTTTTTTCCTCGCGATGG
CCGCAACCAAATACCGGCTGGATGTCAACTTAGCCCGCGTACTGCTCAAACCATTTGGCAATAATCCGAAGTACGTGATG
TTGGGTTTAATGATGATCACCGCAGTGTTCTCGATGTTTATGTCGAACACAGCTACTACGGCCATGATGCTCTCTATTTT
AACGCCAGTGATTGCTGTTTTTGGCCCTAAAGATCCGGGGCGTGTGGCGTTTGCGCTCTGTATTCCGGTGGCCGCTAATA
TTGGAGGTATTGGTACTCCCATAGGGACGCCACCCAATGCAATCGCGTTGAAATATTTGGTGGGCGATAACTTAATTACG
TTTGCCGAATGGATGGCATTTGGGATCCCGTTCGTGGTGATTTTAATGGCGCTCGCTTGGCTGCTGATTGAGTTTATGTA
TCGCGCGGAGCAGAAAACCATTGAATTAACCATCAAAGGTAAGTTTTTAAAAACGCCCAAAGCCATCATTGTTTACATCA
CATTTGCGTCGACCATTTTATTGTGGATGCTCGGTTCACTGCACGGTATGAACTCCTATTCAGTCGCCTTAATCCCTGTC
GCGGTCTTTTCGGTGACCGGCATTATTGGCAAAGAAGATTTAAAAATGATCTCTTGGGATGTGTTGTGGTTAGTTTCTGG
TGGTATTGCTTTAGGTTTAGCCTTAGATAAAACCGGTCTGGCAGAACTGGTTGTTCACAGTATTCCGTTTGACCAATATT
CGCCCTATGTCGTGATTCTCGGTGCGGCTATCCTCTGTTTGCTGATGGCGAATTTTATGTCACACACCGCGACTGCTAAC
TTGCTGATGCCTATCATGGCCGCGCTTGGGGCATCCATGACGCCACTCAATCCTTTGGGCGGTGAGGTGACGCTGATTCT
GGTGGTCACTTTTGCGGCGTCTTTAGGGATGTCATTGCCGATCAGTACGCCACCGAATGCGCTGGCTCATGCAACAAGGA
ATGTACAGAGCCAACAAATGGCAAAAGTGGGCATTATCTTGGGGATTTTTGGGGTACTGATGAGCTTTGTGATGGTGTGG
ATCCTCAACATGGTCGGCCATTAA

Upstream 100 bases:

>100_bases
TCACTTTTGTGTATTCCCCTGTTAAGAAACTTTAATCATTGATCTAACACCAAACATTTCTTTTTTAAGCATCAATAATG
ACGATTGCCGCGGTGATAGC

Downstream 100 bases:

>100_bases
GGAAACGTTATGTCCAACTTAGCGGCCGTTATTGAGCGCTATTTCAACCATGCCGATCGCTGTATTACCTTACCGGCTGG
GTCAATTTTGCTTGCCCAAA

Product: putative transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MPAPRQTHNRFSGRVNMMRPYLKYIIPLLIPMLVLMLPATAFPFEGLTVIQQRVIAIFLLAALLWVFEPIPIYSTSVVII
VLEVLMLSDKGFILFRLGEGTSEFGALLKSTEIMATFANPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGNNPKYVM
LGLMMITAVFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPVAANIGGIGTPIGTPPNAIALKYLVGDNLIT
FAEWMAFGIPFVVILMALAWLLIEFMYRAEQKTIELTIKGKFLKTPKAIIVYITFASTILLWMLGSLHGMNSYSVALIPV
AVFSVTGIIGKEDLKMISWDVLWLVSGGIALGLALDKTGLAELVVHSIPFDQYSPYVVILGAAILCLLMANFMSHTATAN
LLMPIMAALGASMTPLNPLGGEVTLILVVTFAASLGMSLPISTPPNALAHATRNVQSQQMAKVGIILGIFGVLMSFVMVW
ILNMVGH

Sequences:

>Translated_487_residues
MPAPRQTHNRFSGRVNMMRPYLKYIIPLLIPMLVLMLPATAFPFEGLTVIQQRVIAIFLLAALLWVFEPIPIYSTSVVII
VLEVLMLSDKGFILFRLGEGTSEFGALLKSTEIMATFANPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGNNPKYVM
LGLMMITAVFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPVAANIGGIGTPIGTPPNAIALKYLVGDNLIT
FAEWMAFGIPFVVILMALAWLLIEFMYRAEQKTIELTIKGKFLKTPKAIIVYITFASTILLWMLGSLHGMNSYSVALIPV
AVFSVTGIIGKEDLKMISWDVLWLVSGGIALGLALDKTGLAELVVHSIPFDQYSPYVVILGAAILCLLMANFMSHTATAN
LLMPIMAALGASMTPLNPLGGEVTLILVVTFAASLGMSLPISTPPNALAHATRNVQSQQMAKVGIILGIFGVLMSFVMVW
ILNMVGH
>Mature_486_residues
PAPRQTHNRFSGRVNMMRPYLKYIIPLLIPMLVLMLPATAFPFEGLTVIQQRVIAIFLLAALLWVFEPIPIYSTSVVIIV
LEVLMLSDKGFILFRLGEGTSEFGALLKSTEIMATFANPIIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGNNPKYVML
GLMMITAVFSMFMSNTATTAMMLSILTPVIAVFGPKDPGRVAFALCIPVAANIGGIGTPIGTPPNAIALKYLVGDNLITF
AEWMAFGIPFVVILMALAWLLIEFMYRAEQKTIELTIKGKFLKTPKAIIVYITFASTILLWMLGSLHGMNSYSVALIPVA
VFSVTGIIGKEDLKMISWDVLWLVSGGIALGLALDKTGLAELVVHSIPFDQYSPYVVILGAAILCLLMANFMSHTATANL
LMPIMAALGASMTPLNPLGGEVTLILVVTFAASLGMSLPISTPPNALAHATRNVQSQQMAKVGIILGIFGVLMSFVMVWI
LNMVGH

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=533, Percent_Identity=25.891181988743, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI31377715, Length=546, Percent_Identity=22.7106227106227, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI219802232, Length=474, Percent_Identity=24.4725738396624, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI301069349, Length=298, Percent_Identity=24.8322147651007, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI19923838, Length=345, Percent_Identity=23.1884057971014, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4506979, Length=143, Percent_Identity=33.5664335664336, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI225637552, Length=143, Percent_Identity=33.5664335664336, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI225637549, Length=143, Percent_Identity=33.5664335664336, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI31795546, Length=339, Percent_Identity=23.3038348082596, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71988385, Length=426, Percent_Identity=28.169014084507, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32565804, Length=425, Percent_Identity=28.2352941176471, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71989118, Length=520, Percent_Identity=22.8846153846154, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI32564681, Length=458, Percent_Identity=26.4192139737991, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319885, Length=444, Percent_Identity=29.5045045045045, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322263, Length=462, Percent_Identity=29.8701298701299, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324340, Length=418, Percent_Identity=30.3827751196172, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281362116, Length=490, Percent_Identity=23.6734693877551, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281362114, Length=489, Percent_Identity=23.5173824130879, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281362112, Length=489, Percent_Identity=23.5173824130879, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281366409, Length=315, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI17737623, Length=315, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24666468, Length=315, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45551633, Length=315, Percent_Identity=21.9047619047619, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 52826; Mature: 52695

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPRQTHNRFSGRVNMMRPYLKYIIPLLIPMLVLMLPATAFPFEGLTVIQQRVIAIFLL
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AALLWVFEPIPIYSTSVVIIVLEVLMLSDKGFILFRLGEGTSEFGALLKSTEIMATFANP
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGNNPKYVMLGLMMITAVFSMFMSNTATT
HHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
AMMLSILTPVIAVFGPKDPGRVAFALCIPVAANIGGIGTPIGTPPNAIALKYLVGDNLIT
HHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHH
FAEWMAFGIPFVVILMALAWLLIEFMYRAEQKTIELTIKGKFLKTPKAIIVYITFASTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCEEEEEHHHHHHHH
LWMLGSLHGMNSYSVALIPVAVFSVTGIIGKEDLKMISWDVLWLVSGGIALGLALDKTGL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCH
AELVVHSIPFDQYSPYVVILGAAILCLLMANFMSHTATANLLMPIMAALGASMTPLNPLG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEVTLILVVTFAASLGMSLPISTPPNALAHATRNVQSQQMAKVGIILGIFGVLMSFVMVW
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILNMVGH
HHHHHCC
>Mature Secondary Structure 
PAPRQTHNRFSGRVNMMRPYLKYIIPLLIPMLVLMLPATAFPFEGLTVIQQRVIAIFLL
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
AALLWVFEPIPIYSTSVVIIVLEVLMLSDKGFILFRLGEGTSEFGALLKSTEIMATFANP
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
IIMLFLGGFFLAMAATKYRLDVNLARVLLKPFGNNPKYVMLGLMMITAVFSMFMSNTATT
HHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
AMMLSILTPVIAVFGPKDPGRVAFALCIPVAANIGGIGTPIGTPPNAIALKYLVGDNLIT
HHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHH
FAEWMAFGIPFVVILMALAWLLIEFMYRAEQKTIELTIKGKFLKTPKAIIVYITFASTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCEEEEEHHHHHHHH
LWMLGSLHGMNSYSVALIPVAVFSVTGIIGKEDLKMISWDVLWLVSGGIALGLALDKTGL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCH
AELVVHSIPFDQYSPYVVILGAAILCLLMANFMSHTATANLLMPIMAALGASMTPLNPLG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GEVTLILVVTFAASLGMSLPISTPPNALAHATRNVQSQQMAKVGIILGIFGVLMSFVMVW
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
ILNMVGH
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA