| Definition | Vibrio cholerae M66-2 chromosome I, complete genome. |
|---|---|
| Accession | NC_012578 |
| Length | 2,892,523 |
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The map label for this gene is dctB [H]
Identifier: 227081486
GI number: 227081486
Start: 1355938
End: 1357287
Strand: Direct
Name: dctB [H]
Synonym: VCM66_1270
Alternate gene names: 227081486
Gene position: 1355938-1357287 (Clockwise)
Preceding gene: 227081485
Following gene: 227081487
Centisome position: 46.88
GC content: 49.78
Gene sequence:
>1350_bases ATGTCCAACTTAGCGGCCGTTATTGAGCGCTATTTCAACCATGCCGATCGCTGTATTACCTTACCGGCTGGGTCAATTTT GCTTGCCCAAAATGGTTATAACGATCGGCTTTACTATTTACGAAGTGGCCACGTTTCTGGCTATTTTGCGGAAAAAGGTG AGCGGCGCATTAAAGTTTTTTCTGCCGCTTCCGGCGCATTTATTGGGGTACACAGTTTTTTCTCTGGCTTGTGGACGGCG TCATCCACTGTGATTGCCGATAGTGAGGTCGAGTTAGCGTGGATTGATCGTGATACACCAGTGCAGGATGTGGAGCAGTA TGGTTCACTCAGCACTCAATTCATGCCTGTGATTGTGGCTGAGTTATCTCAGCGGCAGCGAAGAGCCACTCAAGAAGCGG TTGCCAAAGAACGTGCTTTAGAGCGGCTATATTCTGCTGAGCAGATGACGACGCTGGGCCAGCTCGCGGCGGGCATTGCT CATGAGCTCAACAATGCGATTGGGGTGGTCAGCAGTAAAACAGAACGCCTAGAAGCCTTGTTTATGGAGTTACTGGAAGA AGTGCATCCAGAAGCGAGTCAGTTTTTCGATTTTGGTTTGCTGTTTGGGCAGAAAGTGTCGTCCAGTGAAGCGCGTGAAC GCGGTGCTGTGTTTGAAAAGCAGTATCAGCTACCCAAAGATATCGCCCGCGAGTTAGCCCGCGCGGTTCCCGCTAATGAG CTTTCCGCTCACTGGCTGAAAAATCCGCATTTAGCGATTCGTTATTGGCAGATGGGGCGAGATTTGCATGACTTGCGATT GGCCGCAAAACATTCGGTTGGGATAGTCAAATCGGTTAAGCAGCTTGGTCGAGCGGATATTCGCTTGGATGAAGAAGTGG ATTTGAACAGCACCATCAATCGCGCTTTGGCCCTGTTACAAAGTGACTTACGTCGTGTGTCCGTGCGGATGCGTCCGGGA AGTTTACCCATCATCAAAGGCTCGCAAACCGAGTGGGTACAGGTGTGGATCAATTTAATTAAAAACGCCTGTGATGCGAT GGCGCAAACCACGGAACCTACGATTGATATTCAAACCCGCTGTTCTCGCCAGCGTCTATACGTGACGGTCGCCAATAATG GACCAGAAATAGATGAGGCCACGCGGCGTAAGATTTTCCAACCCAGTTTTACCACCAAGAAAGAGGGGCTCTCGTTTGGG CTTGGGCTGGGGCTGGCGATTGTCAAACGTATTGTCTCTGGCTATGGCGGAACCGTTGCGGTGAAAAGCGATCAGGACAA AACCATTTTTAGGATTAAATTACCAGTTGAGGGATACCATGGAGAAACTGAACATCATTTGCGTGGATGA
Upstream 100 bases:
>100_bases ACAAATGGCAAAAGTGGGCATTATCTTGGGGATTTTTGGGGTACTGATGAGCTTTGTGATGGTGTGGATCCTCAACATGG TCGGCCATTAAGGAAACGTT
Downstream 100 bases:
>100_bases TCAACGCGAAGTACTGAGTGCGGTGTTACAGGATTTAGAGCCCTTGAGCCGCTGGATCAATATTGAAGACTGCGAATCGG CAGACGAAGCTTTGGAGCTG
Product: sensor histidine kinase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 449; Mature: 448
Protein sequence:
>449_residues MSNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVFSAASGAFIGVHSFFSGLWTA SSTVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVAELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIA HELNNAIGVVSSKTERLEALFMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANE LSAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTINRALALLQSDLRRVSVRMRPG SLPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTRCSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFG LGLGLAIVKRIVSGYGGTVAVKSDQDKTIFRIKLPVEGYHGETEHHLRG
Sequences:
>Translated_449_residues MSNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVFSAASGAFIGVHSFFSGLWTA SSTVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVAELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIA HELNNAIGVVSSKTERLEALFMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANE LSAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTINRALALLQSDLRRVSVRMRPG SLPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTRCSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFG LGLGLAIVKRIVSGYGGTVAVKSDQDKTIFRIKLPVEGYHGETEHHLRG >Mature_448_residues SNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVFSAASGAFIGVHSFFSGLWTAS STVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVAELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIAH ELNNAIGVVSSKTERLEALFMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANEL SAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTINRALALLQSDLRRVSVRMRPGS LPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTRCSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFGL GLGLAIVKRIVSGYGGTVAVKSDQDKTIFRIKLPVEGYHGETEHHLRG
Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 histidine kinase domain [H]
Homologues:
Organism=Escherichia coli, GI1790436, Length=150, Percent_Identity=35.3333333333333, Blast_Score=75, Evalue=1e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR004358 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR017055 - InterPro: IPR009082 [H]
Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 50155; Mature: 50024
Theoretical pI: Translated: 8.71; Mature: 8.71
Prosite motif: PS50042 CNMP_BINDING_3 ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVF CCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCEEECCCCCCEEEEE SAASGAFIGVHSFFSGLWTASSTVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVA ECCCCCEEEHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHH ELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIAHELNNAIGVVSSKTERLEAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH FMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANE HHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCHHHHHHHHHHHCCCCH LSAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTIN HHHHHHCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH RALALLQSDLRRVSVRMRPGSLPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTR HHHHHHHHHHHHHEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHC CSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFGLGLGLAIVKRIVSGYGGTVA CCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE VKSDQDKTIFRIKLPVEGYHGETEHHLRG EECCCCCEEEEEEECCCCCCCCCCCCCCC >Mature Secondary Structure SNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVF CHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCEEECCCCCCEEEEE SAASGAFIGVHSFFSGLWTASSTVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVA ECCCCCEEEHHHHHHHHHHCCCEEEECCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHH ELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIAHELNNAIGVVSSKTERLEAL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH FMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANE HHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHCCHHHHHHHHHHHCCCCH LSAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTIN HHHHHHCCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH RALALLQSDLRRVSVRMRPGSLPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTR HHHHHHHHHHHHHEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHC CSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFGLGLGLAIVKRIVSGYGGTVA CCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE VKSDQDKTIFRIKLPVEGYHGETEHHLRG EECCCCCEEEEEEECCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]