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The map label for this gene is purC [H]

Identifier: 227081362

GI number: 227081362

Start: 1221875

End: 1223092

Strand: Reverse

Name: purC [H]

Synonym: VCM66_1145

Alternate gene names: 227081362

Gene position: 1223092-1221875 (Counterclockwise)

Preceding gene: 227081363

Following gene: 227081360

Centisome position: 42.28

GC content: 46.88

Gene sequence:

>1218_bases
TTGCTTTTTGTCTGGCAGCATAAATTAGTTCTGGTATCATGCGCTCAGCCCGCGGTTTTTCACTCAGCGAAATCGCTAAA
ACGATGTTTGAATTCAGATAGGAATGTCTCAATGAGCCTTGCAGATCAAGTCCTTGCCGTCAATGACGACCTCCCCATTC
GTACCCATCAGCCAGTACATAGCGGTAAAGTTCGCTCGGTTTACTGGCTGACTGAGCAAGACAGCCGACGCCTAATTAAA
GAAAAAGGTTATCCGGTTGCAGAAGATGCCCCGCTGGCCATTATGGTCATCAGTGATCGTATTTCAGCCTTCGATTGCAT
TTGGCACGCGGAAGGCGGTGTCCATGGTGTACCGGGTAAAGGTGCGGCGCTCAATGCTATCTCGAATCATTGGTTCAAAC
TGTTCAAGCAACATGGTTTGGCGGAAAGTCATATTCTCGACATTCCTCACCCTTTTGTGTGGATTGTACAAAAAGCCCGT
CCTATCAAAATTGAAGCCATCTGCCGTCAATACATTACTGGCTCAATGTGGCGTGCTTACGCCAAAGGTGAGCGCGAGTT
TTGTGGTATTACCCTACCAGAAGGTTTAGAGAAGGACAGTCAACTGCCAGAGCTACTGATGACCCCGTCAACCAAAGGTA
TTCTGCGCGGCATCCCCGGCGTGCCAGAAGCCGATGACGTGAATATCTCGCGCCAAGATATTGAAGCCAATTACGCAGCA
TTCAACTTCAATCAACCACAAGATATTGACCATTACGAAACTCTGCTCAAGCAAGGTTTTGCTGTGATCAGCGAAGCGTT
AAAAAGCGTGGGACAACTCTTTGTCGATACCAAATTTGAATTTGGCTACGTAGCAGATCAGCAAGGACAGCAAAAACTGA
TCTATATGGATGAAGTAGGCACCCCTGACTCATCACGCATTTGGGATGCGCAGCAATATCAGCAAGGCAAGATTGTCGAA
AATTCCAAAGAGGGATTCCGCCAATTTTTGCTGAACTACTTCCCAGACCCAGACATTTTACTCAACAAAGATCGCATGCC
TGAACGTGAAGCGCTCGCGCGTGACAATGCTTTACCGCTGGAAGCATTAATGGATATCTCGCGGACCTATTTGGGTATTG
CTGAAAAGATCACGGGGCAACCTATCCATCTGAGTCATCAGCCAAAACAGGAAATCATCGCAATCCTAGATAAAGAATAT
GGGCTGATTGAAAGATAA

Upstream 100 bases:

>100_bases
CTGTGAGCTGTTTTTTATTAAGCAAACCACGCATTCACTGCACTGATCCATAAACAACCTTTACTTAAACAATCTGGCAG
GGATAAATTTAAGCAAACGT

Downstream 100 bases:

>100_bases
ACTCCATCTGCGGCTTTTGTTATGCCTCGCTGCTTTGAATCATAAGCCAGCGGCAAGCACGAGCCAGCAACGGATGAAAA
ACTAAGGGGCTTATTTGCTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MLFVWQHKLVLVSCAQPAVFHSAKSLKRCLNSDRNVSMSLADQVLAVNDDLPIRTHQPVHSGKVRSVYWLTEQDSRRLIK
EKGYPVAEDAPLAIMVISDRISAFDCIWHAEGGVHGVPGKGAALNAISNHWFKLFKQHGLAESHILDIPHPFVWIVQKAR
PIKIEAICRQYITGSMWRAYAKGEREFCGITLPEGLEKDSQLPELLMTPSTKGILRGIPGVPEADDVNISRQDIEANYAA
FNFNQPQDIDHYETLLKQGFAVISEALKSVGQLFVDTKFEFGYVADQQGQQKLIYMDEVGTPDSSRIWDAQQYQQGKIVE
NSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNALPLEALMDISRTYLGIAEKITGQPIHLSHQPKQEIIAILDKEY
GLIER

Sequences:

>Translated_405_residues
MLFVWQHKLVLVSCAQPAVFHSAKSLKRCLNSDRNVSMSLADQVLAVNDDLPIRTHQPVHSGKVRSVYWLTEQDSRRLIK
EKGYPVAEDAPLAIMVISDRISAFDCIWHAEGGVHGVPGKGAALNAISNHWFKLFKQHGLAESHILDIPHPFVWIVQKAR
PIKIEAICRQYITGSMWRAYAKGEREFCGITLPEGLEKDSQLPELLMTPSTKGILRGIPGVPEADDVNISRQDIEANYAA
FNFNQPQDIDHYETLLKQGFAVISEALKSVGQLFVDTKFEFGYVADQQGQQKLIYMDEVGTPDSSRIWDAQQYQQGKIVE
NSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNALPLEALMDISRTYLGIAEKITGQPIHLSHQPKQEIIAILDKEY
GLIER
>Mature_405_residues
MLFVWQHKLVLVSCAQPAVFHSAKSLKRCLNSDRNVSMSLADQVLAVNDDLPIRTHQPVHSGKVRSVYWLTEQDSRRLIK
EKGYPVAEDAPLAIMVISDRISAFDCIWHAEGGVHGVPGKGAALNAISNHWFKLFKQHGLAESHILDIPHPFVWIVQKAR
PIKIEAICRQYITGSMWRAYAKGEREFCGITLPEGLEKDSQLPELLMTPSTKGILRGIPGVPEADDVNISRQDIEANYAA
FNFNQPQDIDHYETLLKQGFAVISEALKSVGQLFVDTKFEFGYVADQQGQQKLIYMDEVGTPDSSRIWDAQQYQQGKIVE
NSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNALPLEALMDISRTYLGIAEKITGQPIHLSHQPKQEIIAILDKEY
GLIER

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=328, Percent_Identity=27.4390243902439, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 45800; Mature: 45800

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS01057 SAICAR_SYNTHETASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFVWQHKLVLVSCAQPAVFHSAKSLKRCLNSDRNVSMSLADQVLAVNDDLPIRTHQPVH
CEEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHCEEEECCCCCCCCCCCCC
SGKVRSVYWLTEQDSRRLIKEKGYPVAEDAPLAIMVISDRISAFDCIWHAEGGVHGVPGK
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
GAALNAISNHWFKLFKQHGLAESHILDIPHPFVWIVQKARPIKIEAICRQYITGSMWRAY
CHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHH
AKGEREFCGITLPEGLEKDSQLPELLMTPSTKGILRGIPGVPEADDVNISRQDIEANYAA
HCCCCCEECEECCCCCCCCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCCEEE
FNFNQPQDIDHYETLLKQGFAVISEALKSVGQLFVDTKFEFGYVADQQGQQKLIYMDEVG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECCC
TPDSSRIWDAQQYQQGKIVENSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNALPL
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCCCCCH
EALMDISRTYLGIAEKITGQPIHLSHQPKQEIIAILDKEYGLIER
HHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLFVWQHKLVLVSCAQPAVFHSAKSLKRCLNSDRNVSMSLADQVLAVNDDLPIRTHQPVH
CEEEEECCEEEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHCEEEECCCCCCCCCCCCC
SGKVRSVYWLTEQDSRRLIKEKGYPVAEDAPLAIMVISDRISAFDCIWHAEGGVHGVPGK
CCCCEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCC
GAALNAISNHWFKLFKQHGLAESHILDIPHPFVWIVQKARPIKIEAICRQYITGSMWRAY
CHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHEEEECCCCCCCHHHHHHHHHHHHHHHHH
AKGEREFCGITLPEGLEKDSQLPELLMTPSTKGILRGIPGVPEADDVNISRQDIEANYAA
HCCCCCEECEECCCCCCCCCCCCHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHCCCCEEE
FNFNQPQDIDHYETLLKQGFAVISEALKSVGQLFVDTKFEFGYVADQQGQQKLIYMDEVG
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECCC
TPDSSRIWDAQQYQQGKIVENSKEGFRQFLLNYFPDPDILLNKDRMPEREALARDNALPL
CCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHCCCCCCH
EALMDISRTYLGIAEKITGQPIHLSHQPKQEIIAILDKEYGLIER
HHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]