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The map label for this gene is vicH [H]

Identifier: 227081303

GI number: 227081303

Start: 1155605

End: 1156018

Strand: Reverse

Name: vicH [H]

Synonym: VCM66_1086

Alternate gene names: 227081303

Gene position: 1156018-1155605 (Counterclockwise)

Preceding gene: 227081313

Following gene: 227081301

Centisome position: 39.97

GC content: 43.0

Gene sequence:

>414_bases
ATGGTAATGTCGGAAATCACTAAGACTTTATTAAATATTCGTAGCCTACGTGCTTATGCACGCGAACTGACTATTGAGCA
ACTTGAAGAAGCGTTAGATAAATTAACGACCGTCGTTCAAGAGCGTAAAGAAGCAGAAGCAGAAGAAATTGCTGCTCGTG
CAGAGCAAGAAGCGAAATTAGCCGCAATTGCTGAACAAATTGCTAAAGATAGTATCGACCTCGAAGCGCTTATTTCTGCG
CTATCAGGCGAAACTAAAACGAAAGCAAAAGGCAAACGTGCACCTCGCCCTGCAAAATACAAGTATATCGACACCAACGG
TGAAGAAAAAACTTGGACAGGCCAAGGCCGTACTCCTTCAGTGATCCAAAAAGCACTGGATGAAGGTAAATCTCTGGAAG
AATTCGCTCTGTAA

Upstream 100 bases:

>100_bases
TTTACTTTCTTACTATTTTGACTTAATATTTGCAGCGAAAACTTGTCAGTATAATAAGCTAGGTTTAGTATTAACTCGTT
ATCCAAATTGTGAACAGGAA

Downstream 100 bases:

>100_bases
TTTTGCCAGAAACTAAAATGATAAAGGCTCCCGAAGGAGCCTTTTTGTTATCTTTCCCAATAAGCCTCTTCAAGGCTATC
TTCTCGCTCAGGAAGACCAC

Product: DNA-binding protein VicH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MVMSEITKTLLNIRSLRAYARELTIEQLEEALDKLTTVVQERKEAEAEEIAARAEQEAKLAAIAEQIAKDSIDLEALISA
LSGETKTKAKGKRAPRPAKYKYIDTNGEEKTWTGQGRTPSVIQKALDEGKSLEEFAL

Sequences:

>Translated_137_residues
MVMSEITKTLLNIRSLRAYARELTIEQLEEALDKLTTVVQERKEAEAEEIAARAEQEAKLAAIAEQIAKDSIDLEALISA
LSGETKTKAKGKRAPRPAKYKYIDTNGEEKTWTGQGRTPSVIQKALDEGKSLEEFAL
>Mature_137_residues
MVMSEITKTLLNIRSLRAYARELTIEQLEEALDKLTTVVQERKEAEAEEIAARAEQEAKLAAIAEQIAKDSIDLEALISA
LSGETKTKAKGKRAPRPAKYKYIDTNGEEKTWTGQGRTPSVIQKALDEGKSLEEFAL

Specific function: Binds tightly to ds-DNA, increases its thermal stability and inhibits transcription [H]

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family [H]

Homologues:

Organism=Escherichia coli, GI1787489, Length=136, Percent_Identity=54.4117647058823, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789023, Length=135, Percent_Identity=48.1481481481481, Blast_Score=112, Evalue=7e-27,

Paralogues:

None

Copy number: 820 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1780 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1020 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 4632 Molecules/Cell In: Gr

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001801 [H]

Pfam domain/function: PF00816 Histone_HNS [H]

EC number: NA

Molecular weight: Translated: 15191; Mature: 15191

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSEITKTLLNIRSLRAYARELTIEQLEEALDKLTTVVQERKEAEAEEIAARAEQEAKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIAEQIAKDSIDLEALISALSGETKTKAKGKRAPRPAKYKYIDTNGEEKTWTGQGRTPS
HHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHH
VIQKALDEGKSLEEFAL
HHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MVMSEITKTLLNIRSLRAYARELTIEQLEEALDKLTTVVQERKEAEAEEIAARAEQEAKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIAEQIAKDSIDLEALISALSGETKTKAKGKRAPRPAKYKYIDTNGEEKTWTGQGRTPS
HHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHH
VIQKALDEGKSLEEFAL
HHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]