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The map label for this gene is nagC [H]

Identifier: 227081167

GI number: 227081167

Start: 1015937

End: 1017151

Strand: Reverse

Name: nagC [H]

Synonym: VCM66_0949

Alternate gene names: 227081167

Gene position: 1017151-1015937 (Counterclockwise)

Preceding gene: 227081168

Following gene: 227081166

Centisome position: 35.16

GC content: 46.91

Gene sequence:

>1215_bases
ATGAATGGCGGACAGATTGGTAACGTAGATTTAGTTAAACAGCTAAACAGTGCGGCGGTTTACCGCTTGATTGACCAACA
AGGCCCAATCAGTCGGATTCAAGTCGCTGATGTAAGCCAACTGGCTCCGGCCAGTGTTACCAAGATTACCCGCCAATTGC
TTGAACGTGGATTAATCAAAGAAGTCGCGCAACAAGCTTCTACAGGTGGTCGGCGAGCCATTTCGCTGACCACAGAAGTC
AAGCCGTTCCACTCTATTGCCGTGCGTATCGGACGTGACTATATTCAACTCAGCCTCTATGACCTAGGTGGAAACTCACT
GGTTGATGAGCATCATGAATTTCACTACAACACGCAAGACGTGTTGATGTCGAGCCTGATTAAACAGATCAAACAATTTA
TTCAACAACACACCGCATTAATTGATCAGTTGATTGCGATTGGTGTGGCCTTACCCGGTTTGGTGAACCCAGAAACAGGT
GTTGTTGAGTACATGCCTAATGTCGCGATCAATGAATTACCTCTCGGCGCAACCATTCGTGATGAGTTCCATGTTGAATG
TTTTGTGGGTAACGACGTTCGTGGTATTGCCTTAGCGGAGCACTATTTCGGAGCAAGCCAAGATTGCCAAGACTCCATAC
TAGTCAGTGTACACCGTGGCACAGGTGCAGGGATTATCGTTAACGGTCAAGTCTTCTTAGGCTATAACCGCAACGTCGGT
GAAATTGGCCACATCCAAATCGACCCTCTTGGTGAGCAATGTCAATGTGGCAACTTTGGTTGTCTAGAAACCGTTGCGAC
CAACCCTGCTATCACTTCTCGTGTGCAAAAACTGATCGCTCAGGGGTATGAATCTTCGCTCTCTACTCTCGATACGATTA
CGATTGATGATGTCTGTGAGCACGCAAATGCTGGGGATGAACTGGCGAAACAAGCGTTGGTTCGTGTAGGTAATCAGTTG
GGTAAGGCGATTGCGATTACCGTAAACCTATTCAACCCACAAAAGATCGTGATTGCTGGGCAAATCACCGCCGCCAAAGA
GATCGTGTTCCCCGCGATTCAACGCAACGTAGAAAATCAGTCACTGAAAACGTTCCACCAACATCTGCCGATTGTGTCTT
CACAAGTCTACAAACAACCCACTATGGGCGCTTTTGCTATGATCAAACGTGCGATGTTAAATGGGGTTCTGTTACAAAAA
TTGCTTGAAGACTGA

Upstream 100 bases:

>100_bases
GTCGTATCAAGAAAGGTATGATCGCCAACCTGACTGTTTTTGATCGTGACTTCAACGTAAAAGCGACGGTAGTTAACGGA
CAATACGAGCAGAATTGATA

Downstream 100 bases:

>100_bases
GCTTTTTAGTTAAGCTTACGCAACCGATTGACCTATAATGACGGTGGTATTTTTATACCACCGTTTTTTTATTATTAAAT
TAAGAATATAGCTCATGGAT

Product: N-acetylglucosamine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTEV
KPFHSIAVRIGRDYIQLSLYDLGGNSLVDEHHEFHYNTQDVLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETG
VVEYMPNVAINELPLGATIRDEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTGAGIIVNGQVFLGYNRNVG
EIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQGYESSLSTLDTITIDDVCEHANAGDELAKQALVRVGNQL
GKAIAITVNLFNPQKIVIAGQITAAKEIVFPAIQRNVENQSLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQK
LLED

Sequences:

>Translated_404_residues
MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTEV
KPFHSIAVRIGRDYIQLSLYDLGGNSLVDEHHEFHYNTQDVLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETG
VVEYMPNVAINELPLGATIRDEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTGAGIIVNGQVFLGYNRNVG
EIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQGYESSLSTLDTITIDDVCEHANAGDELAKQALVRVGNQL
GKAIAITVNLFNPQKIVIAGQITAAKEIVFPAIQRNVENQSLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQK
LLED
>Mature_404_residues
MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPASVTKITRQLLERGLIKEVAQQASTGGRRAISLTTEV
KPFHSIAVRIGRDYIQLSLYDLGGNSLVDEHHEFHYNTQDVLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETG
VVEYMPNVAINELPLGATIRDEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTGAGIIVNGQVFLGYNRNVG
EIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQGYESSLSTLDTITIDDVCEHANAGDELAKQALVRVGNQL
GKAIAITVNLFNPQKIVIAGQITAAKEIVFPAIQRNVENQSLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQK
LLED

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=268, Percent_Identity=22.3880597014925, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI298566325, Length=270, Percent_Identity=21.8518518518519, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI4885285, Length=268, Percent_Identity=22.3880597014925, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI190014632, Length=268, Percent_Identity=22.3880597014925, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786891, Length=401, Percent_Identity=60.0997506234414, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1787878, Length=401, Percent_Identity=39.4014962593516, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI87082127, Length=347, Percent_Identity=22.478386167147, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081733, Length=226, Percent_Identity=25.6637168141593, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 43885; Mature: 43885

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPASVTKITRQLLERGLIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTEVKPFHSIAVRIGRDYIQLSLYDLGGNSLVDEHHEFHYNTQD
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCHHH
VLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETGVVEYMPNVAINELPLGATIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCEEC
DEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTGAGIIVNGQVFLGYNRNVG
CCEEEEEEECCCCCCEEHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECEEEEEECCCCC
EIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQGYESSLSTLDTITIDDVCE
CCCEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHH
HANAGDELAKQALVRVGNQLGKAIAITVNLFNPQKIVIAGQITAAKEIVFPAIQRNVENQ
HCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCHH
SLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQKLLED
HHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNGGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQVADVSQLAPASVTKITRQLLERGLIK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCHHHHHHHHHHHHHHHHH
EVAQQASTGGRRAISLTTEVKPFHSIAVRIGRDYIQLSLYDLGGNSLVDEHHEFHYNTQD
HHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHCCCHHH
VLMSSLIKQIKQFIQQHTALIDQLIAIGVALPGLVNPETGVVEYMPNVAINELPLGATIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCEEC
DEFHVECFVGNDVRGIALAEHYFGASQDCQDSILVSVHRGTGAGIIVNGQVFLGYNRNVG
CCEEEEEEECCCCCCEEHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECEEEEEECCCCC
EIGHIQIDPLGEQCQCGNFGCLETVATNPAITSRVQKLIAQGYESSLSTLDTITIDDVCE
CCCEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHH
HANAGDELAKQALVRVGNQLGKAIAITVNLFNPQKIVIAGQITAAKEIVFPAIQRNVENQ
HCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCHH
SLKTFHQHLPIVSSQVYKQPTMGAFAMIKRAMLNGVLLQKLLED
HHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]