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The map label for this gene is tppB [H]

Identifier: 227081162

GI number: 227081162

Start: 1009762

End: 1011306

Strand: Reverse

Name: tppB [H]

Synonym: VCM66_0944

Alternate gene names: 227081162

Gene position: 1011306-1009762 (Counterclockwise)

Preceding gene: 227081165

Following gene: 227081158

Centisome position: 34.96

GC content: 46.41

Gene sequence:

>1545_bases
TTGACGGTTGGAGCTTCACAACAGACTTCAACCATTGCACTGCACAATGATACAGGAATGCTTATGTCCAACCTTAATAT
CTTTAAACAACCGAATGCCTTCTATTTGATCTTCTCTATCGAGTTTTGGGAACGATTTGGCTTCTACGGTATGCAAGCCA
TTCTGACGGTTTACATGGTCAAAATTATGGGCATGGATGAGTCCGCTTCTTTCGTACTCTTCGGTGCCTTTTCAGCGTTA
GTGTACGGCTTTGTCGCAATTGGCGGTTGGATCGGCGATAAAGTCATTGGAACAAAACGTGCTATTACTCTCGGCGCGAT
TGTCATGATGGTCGGTTATGTTCTGCTTGGACTCTCCACCGCAGATCATCCGCTTGTTGGGCCAACGTTAATCTACATCG
CGATGGGCTTTATTACGGTTGGTAACGGCTTGTTCAAAGCAAACCCTTCGAGTCTACTTGCAAAAATTTACCCAGAGAAT
GATCCTCGCTTAGATGGCGCTTTCACCATGTACTACATGGCGATCAATTTAGGCTCTTTCTTCTCAATGATCATTACTCC
ACTTGTAGCAATCAAGATGGGCTATGGAATGGCATTTGGAGTGAGTGCAGTCGGCCTTGCCATCACTGTGGTGAACTTCC
TATTTTGCTTACGCATGTTAAAAGGCACAGGCTCTCCAGCCGACCTTATGCCGGTGAACAAAATGTATCTGGTTCTTGTC
GCCGTGGGTTCTATCATTGCCAGCCTAGTGTGTAGCTACTTACTACAAAACCTCACCCTAGCACACGGTATTTTGGTTGT
TGCGGGTCTGTTTATTCTGGGATGTTATTTTAAAGAAGCGTTCTCTATGTCTGGGATTGAACGCGCCAAAATGCTGGTTG
CCTTCATCTTGATGCTGCAAGGCGTCGTGTTTTTCGTACTCTATTTCCAAATGCCAACTTCACTGAATTTCTTTGCTATC
AATAACGTTGAGCACCATATCTTTGGTTTTGATGTCGCGCCAGAGCAGTTTCAAGCACTCAATCCGTTTTGGATTATGAT
TGCTAGCCCTATTTTGGCGGCGACTTACGGCAAACTGGGCGATAAATTGGCGATGCCTTTCAAGTTCGCTTTCGGGATGG
CTTTATGTGCGCTCTCTTTCTTAGTATTAAGCTGGGGAACCTTGTTTGCTAACGAACAAGGCATCATTAGCTCAAACTGG
CTTATCGCAAGTTATGCTTTCCAATCCATCGGTGAACTCCTAGTCTCTGGTCTTGGTTTAGCTATGGTCGCGCAATTGGT
ACCACAACGTATGATGGGTTTTGCAATGGGTATGTGGTTCCTCACTTCGGCCTCTGCCGCGGTCATTGCAGGTTGGGTCG
CTAGCCTGACTTCAACGCCGGCTAATGTGTCTGGCGCCACCGAATCACTGCATATTTATGGTGAGGTATTTGCGCAAATT
GGTTATGTGACAGCCGGAATTGCCATCGTCACCTTCATGATTGCTCCTAAGCTGACTCGCATCTGCCGCGGTGAATCAGA
GCCGTTAGAGCTGGTGACGCAATAA

Upstream 100 bases:

>100_bases
CTGAATTCTGAGAAAACCAGTATTGCTCATCATTTATTTTGAATGTATAGGTATCAGCCGAATAAAAAACTCTCATGGAT
GAGTTGAATAAATATAATGT

Downstream 100 bases:

>100_bases
AGATTGAATCATAAATACGCCCCGTGAAACTGAAAACAGCGCCGAATGAGGCGCTGTTTTTGTATGGCTGCTTTATGGAT
GACTCGCTCACATTGGAGCT

Product: putative tripeptide transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYGMQAILTVYMVKIMGMDESASFVLFGAFSAL
VYGFVAIGGWIGDKVIGTKRAITLGAIVMMVGYVLLGLSTADHPLVGPTLIYIAMGFITVGNGLFKANPSSLLAKIYPEN
DPRLDGAFTMYYMAINLGSFFSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFCLRMLKGTGSPADLMPVNKMYLVLV
AVGSIIASLVCSYLLQNLTLAHGILVVAGLFILGCYFKEAFSMSGIERAKMLVAFILMLQGVVFFVLYFQMPTSLNFFAI
NNVEHHIFGFDVAPEQFQALNPFWIMIASPILAATYGKLGDKLAMPFKFAFGMALCALSFLVLSWGTLFANEQGIISSNW
LIASYAFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATESLHIYGEVFAQI
GYVTAGIAIVTFMIAPKLTRICRGESEPLELVTQ

Sequences:

>Translated_514_residues
MTVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYGMQAILTVYMVKIMGMDESASFVLFGAFSAL
VYGFVAIGGWIGDKVIGTKRAITLGAIVMMVGYVLLGLSTADHPLVGPTLIYIAMGFITVGNGLFKANPSSLLAKIYPEN
DPRLDGAFTMYYMAINLGSFFSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFCLRMLKGTGSPADLMPVNKMYLVLV
AVGSIIASLVCSYLLQNLTLAHGILVVAGLFILGCYFKEAFSMSGIERAKMLVAFILMLQGVVFFVLYFQMPTSLNFFAI
NNVEHHIFGFDVAPEQFQALNPFWIMIASPILAATYGKLGDKLAMPFKFAFGMALCALSFLVLSWGTLFANEQGIISSNW
LIASYAFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATESLHIYGEVFAQI
GYVTAGIAIVTFMIAPKLTRICRGESEPLELVTQ
>Mature_513_residues
TVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYGMQAILTVYMVKIMGMDESASFVLFGAFSALV
YGFVAIGGWIGDKVIGTKRAITLGAIVMMVGYVLLGLSTADHPLVGPTLIYIAMGFITVGNGLFKANPSSLLAKIYPEND
PRLDGAFTMYYMAINLGSFFSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFCLRMLKGTGSPADLMPVNKMYLVLVA
VGSIIASLVCSYLLQNLTLAHGILVVAGLFILGCYFKEAFSMSGIERAKMLVAFILMLQGVVFFVLYFQMPTSLNFFAIN
NVEHHIFGFDVAPEQFQALNPFWIMIASPILAATYGKLGDKLAMPFKFAFGMALCALSFLVLSWGTLFANEQGIISSNWL
IASYAFQSIGELLVSGLGLAMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATESLHIYGEVFAQIG
YVTAGIAIVTFMIAPKLTRICRGESEPLELVTQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=391, Percent_Identity=25.8312020460358, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI226371746, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787922, Length=480, Percent_Identity=58.9583333333333, Blast_Score=565, Evalue=1e-162,
Organism=Escherichia coli, GI1789911, Length=490, Percent_Identity=48.1632653061224, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1790572, Length=476, Percent_Identity=30.4621848739496, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786927, Length=469, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17541704, Length=383, Percent_Identity=27.154046997389, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71987453, Length=414, Percent_Identity=24.8792270531401, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571098, Length=333, Percent_Identity=27.6276276276276, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28571102, Length=333, Percent_Identity=27.6276276276276, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28571100, Length=333, Percent_Identity=27.6276276276276, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24639581, Length=332, Percent_Identity=29.2168674698795, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639583, Length=332, Percent_Identity=29.2168674698795, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24639585, Length=332, Percent_Identity=29.2168674698795, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55556; Mature: 55425

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYGMQAILTVYMV
CCCCCCCCCCEEEEECCCCHHHHCCHHEECCCEEEEEEEEHHHHHHCHHHHHHHHHHHHH
KIMGMDESASFVLFGAFSALVYGFVAIGGWIGDKVIGTKRAITLGAIVMMVGYVLLGLST
HHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHCCC
ADHPLVGPTLIYIAMGFITVGNGLFKANPSSLLAKIYPENDPRLDGAFTMYYMAINLGSF
CCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHH
FSMIITPLVAIKMGYGMAFGVSAVGLAITVVNFLFCLRMLKGTGSPADLMPVNKMYLVLV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
AVGSIIASLVCSYLLQNLTLAHGILVVAGLFILGCYFKEAFSMSGIERAKMLVAFILMLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
GVVFFVLYFQMPTSLNFFAINNVEHHIFGFDVAPEQFQALNPFWIMIASPILAATYGKLG
HHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
DKLAMPFKFAFGMALCALSFLVLSWGTLFANEQGIISSNWLIASYAFQSIGELLVSGLGL
CHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHH
AMVAQLVPQRMMGFAMGMWFLTSASAAVIAGWVASLTSTPANVSGATESLHIYGEVFAQI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
GYVTAGIAIVTFMIAPKLTRICRGESEPLELVTQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure 
TVGASQQTSTIALHNDTGMLMSNLNIFKQPNAFYLIFSIEFWERFGFYGMQAILTVYMV
CCCCCCCCCEEEEECCCCHHHHCCHHEECCCEEEEEEEEHHHHHHCHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA