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The map label for this gene is citC [H]

Identifier: 227080975

GI number: 227080975

Start: 810617

End: 811687

Strand: Direct

Name: citC [H]

Synonym: VCM66_0754

Alternate gene names: 227080975

Gene position: 810617-811687 (Clockwise)

Preceding gene: 227080968

Following gene: 227080976

Centisome position: 28.02

GC content: 45.28

Gene sequence:

>1071_bases
GTGAGGAAGCCGACCATGGTGGATATTTATACCTTCTCGCGAGTTTCAACCAAGAATCGAACCAAGCTCTTACAGATCAA
AGAGTTTCTCTGCCAGCATCAGCTGACCGTAGATGACGATGTCGAGCATTTTGTGGTGGCTTATGGCACAAACCAAATCA
TCGCTTGCGGTGGAATTGCGGGGCACGTGTTGAAGTCCATCGCGGTTTCTCCTGCGCTGCAAGGCACTGGTTTTGCGCTC
AAACTGATGACCGAATTAACCAACTTCGCTTATGAAATGGGGCGCTTTTCACTCTTTCTATTTACTAAGCCAGCCAATAT
TGATTTATTTAGACAGTGTGGTTTTTTCTTGGTCGATAAAGTCGAACCGCATATTGCTTTATTAGAAAATAGCCCTAATC
GCCTTTCTGTTTATTGCAAACAGTTGCAGTTATTAAAAATGTCTGGGCGTAAAATTGGCAGTATTGTGATGAATGCCAAT
CCATTTACCTTAGGTCATCAATATTTAATTGAACAAGCCTGTGAACAATGTGACTGGGTGCATTTATTTGTTGTAAAAGC
AGAGAATAAAGATTTTTCTTACGCTGATCGCATGGCCATGATTAAGGCGGGTAGTAAACATTTATTGAATTTAACTATTC
ATTCCGGCTCAGATTATATTATTTCGCGCGCGACCTTCCCCAGTTATTTTATTAAAGATCAGCAAGTGGTCAATCAATCC
CATACTGCGCTGGATTTAAGTATTTTCCGCCATTCAATCGCGCCAGCACTTGGCATTACGCACCGCTTTGTCGGCAGTGA
GCCGATTTGTACGGTGACGCGTCACTACAACCAAGCCATGCGCCGCTGGCTAGAAGAAGCGCACGATGCCAGTGCGCCGA
TCCAAGTGGTTGAAATTGAGCGCAGTCAACAAGCCTCGCAGCCAATTTCAGCATCGCGCGTGCGTTACTTGCTCAAACAA
TTTGGCTTTGCTGCGATTGCCGATCTCGTGCCGAAAACGACCTATTCCTACCTTTGCCAGCACTATGCGGAACATTCGCT
ACAGACCGCACCGCAACTGTTAGCGGTATGA

Upstream 100 bases:

>100_bases
ATTCATTAAAACCATAAAGAGCGTTAACGGCGGGAAATAAAGTGATTACCCTCATTAAACCTTTTCGGCTGAATTTAGAT
AATAAAGCCAGAAAAAATAG

Downstream 100 bases:

>100_bases
GGGCGGTGCTGACACTGTTTTATCCAATAACTCATTAACAAGGTTGTACCCATGAAAATTGCCCATCCCGCCTTTGCGGG
AACACTGGAATCCAGTGATC

Product: citrate (pro-3S)-lyase ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASAPIQVVEIERSQQASQPISASRVRYLLKQ
FGFAAIADLVPKTTYSYLCQHYAEHSLQTAPQLLAV

Sequences:

>Translated_356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASAPIQVVEIERSQQASQPISASRVRYLLKQ
FGFAAIADLVPKTTYSYLCQHYAEHSLQTAPQLLAV
>Mature_356_residues
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIAGHVLKSIAVSPALQGTGFAL
KLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDKVEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNAN
PFTLGHQYLIEQACEQCDWVHLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASAPIQVVEIERSQQASQPISASRVRYLLKQ
FGFAAIADLVPKTTYSYLCQHYAEHSLQTAPQLLAV

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=339, Percent_Identity=51.0324483775811, Blast_Score=351, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 40179; Mature: 40179

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIA
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHH
GHVLKSIAVSPALQGTGFALKLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCEEEEC
VEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNANPFTLGHQYLIEQACEQCDWV
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
EEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCHHHHCHHHHHCCC
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASAPIQVVEIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
RSQQASQPISASRVRYLLKQFGFAAIADLVPKTTYSYLCQHYAEHSLQTAPQLLAV
HHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MRKPTMVDIYTFSRVSTKNRTKLLQIKEFLCQHQLTVDDDVEHFVVAYGTNQIIACGGIA
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCHH
GHVLKSIAVSPALQGTGFALKLMTELTNFAYEMGRFSLFLFTKPANIDLFRQCGFFLVDK
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCEEEEC
VEPHIALLENSPNRLSVYCKQLQLLKMSGRKIGSIVMNANPFTLGHQYLIEQACEQCDWV
CCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEE
HLFVVKAENKDFSYADRMAMIKAGSKHLLNLTIHSGSDYIISRATFPSYFIKDQQVVNQS
EEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCCHHHHCHHHHHCCC
HTALDLSIFRHSIAPALGITHRFVGSEPICTVTRHYNQAMRRWLEEAHDASAPIQVVEIE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
RSQQASQPISASRVRYLLKQFGFAAIADLVPKTTYSYLCQHYAEHSLQTAPQLLAV
HHHHCCCCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]