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The map label for this gene is yciR [C]

Identifier: 227080839

GI number: 227080839

Start: 659057

End: 661114

Strand: Reverse

Name: yciR [C]

Synonym: VCM66_0616

Alternate gene names: 227080839

Gene position: 661114-659057 (Counterclockwise)

Preceding gene: 227080841

Following gene: 227080834

Centisome position: 22.86

GC content: 47.23

Gene sequence:

>2058_bases
ATGACCAAATTTCGCAAGATTCATTCTTTGGCCTTTAAGCAAGCCAAAAGCGTGTTTTTAGTCTCTGTACTGTTGGGACT
CTGTTTTAGTTTTTACCACACCTTGTCCGACCTGCACCAAGAGCAGAGCAAGGTGCAGGAGCACTATAACTTTAAATTGG
TGCAGAGTTATGAAAACGCCAGTCAAGCGGCTTACCATCTTAATAATCTACTCGCCGAGCAAGTCGCCACCACCTTGATG
CTCGACCCCGGCATATTCAAAGTGGAGATTGTGGATGACTTTGGCGATGTGATGACCCGTAAAGAAAAAGCAATCAGTGA
ACAGAGTCAATTAGTCAGTGTACTCGCCAGCTATCTTACTCCTGCGGTTTCCGTGTTTAGTGCCGAGCTGCATCAGCCTA
ACTCCAACGTGGTGGTCGGCAAACTGAGCTTCTATATCGATGGCTCGTCAATAGCCAAAGTGTTCATCGCCAAAACCACT
CGCGTACTGCTCTTCGACCTATTACGTAATACGCTATTGACGACCATTTTACTGCTGTTTTTCTACCAAAAGCTCTCTCG
CCCAATCACCATGCTGATCACTTGGGTTAACTCACTCAATGACACACAGCGCTCACCTCTGCCTCTTCGTCTTACTCATG
ACGATGAACTCAGTGAGCTCGCGTCGACGTTTCAATCGATGTGGAAAGGCAAAGAGCTGGCAGAATCGAAACTCAATCAA
TTGGCTTATTATGACAGCCTCACAGGCCTCGCCAATCGCAGTTTGTTGCTGCAAAAATTGAGTGATGCGATTGAAACTGC
GCAAAACTCGCATAGCACAGGCGTACTGTTCTATCTCGACTTGGATCGCTTTAAAACTATTAATGACTCACTCGGTCATA
CCATCGGTGACCAGTTGATTAAAGCCGTGGCGCTGCGTATGGAGGCATGGACTAAAAACGACTACCTGTCAGCACGAATT
GGTGGCGATGAGTTCGCAGTGCTGATCCCTTATCTCTCGCCTGCGAAAGCTGAGGAAGTGGCCAAGCAGCTACTCACTCT
GATTTCCAACCCTTATGCGGTGGACGATCACCAGTTCTACTGTACCGTGAGTATCGGGATTTCGGTTTTCCCTTCCGTAG
GAAGCTGTAATATTGATGTATTACGTCAAGCGGATACCGCACTGTATCGCGCCAAAGCCAGTGGGCGTAACAAGTTCATG
TTCTATGAGCCGGAAATGCAGGCGCAGGTGGAGTCTTTCCTTGAAATTGAAAAAGGCTTGCATGAAGCGCTCAATCAGCG
CCAACTCGAGCTTTTCTACCAACCTCAGGTCGACGAGCAGCACAACATTATTGGTGTCGAAGCGCTGATCCGCTGGAACC
ATCCTAAACGAGGGTTGTTGCCTCCCGGTGTTTTTATGCCGATCGCAGAAGAAACAGGACAAATTTTACCGATAGGCAAC
TGGATCATTGAGCAAGCGTGTTATCAATATGCCCAGTGGAAAAAACAAGGCATTTTACCGCCCCATTTTCGCCGTTTGGC
GATCAATATCAGCCCACTACAGTTTGCTCAGGAGTCTTTTATTGAGCAGGTGAACCACGCTTTACGCCAAGCAGGGATCA
CGGGGGAGCCGATAGAATTAGAGATAACTGAAAGCTTACTGCTGGAAAACGTTGAGAGCGCCATAGAAAAAATGGCCAAG
TTGAAAGAGAGCCAAATCAGTATTTCGATTGATGACTTTGGAACAGGCTACTCTTCGCTGCGTTACCTCAAGCATCTTGC
GGTCGATGTGCTGAAAATTGACCGCTCGTTTGTCAATCAACTGCACCTTGATGATAACGATCAAGCGATCGTCGACACAA
TCTTAGCGATTGCCAGAAAACTGAATTTAGAAGTGATTGCCGAAGGGGTGGAAGACACCTCTGAGTTGGCCGCACTCAAA
AAACTGGGGTGTAACCAATTCCAAGGCTACCTGTTTGATAAACCGCTGCGAGCCGAAGAGATTGCACAGCGTTTTGTCAG
CAACAGTTATCGCAAAATTCAAACCTTACCCGTTGCGACAAACAGTTTACAAAAATAG

Upstream 100 bases:

>100_bases
TTCAATGAGTGAATTCATATTTTCTCATGGCAGTTTTAATTAATTTATCAATAAATTTGGACTATAACTGTAGAGAGTAG
AAAAAAATGAAGTCGGGCCT

Downstream 100 bases:

>100_bases
GTAGCTCATGATGATCGCATCTTCACTTTTACCCTTTGCCACGGGGTAATAGTTAACACGGCGATCGATTTCATTAAACC
CCGCTCGCTGATACAGCGCA

Product: c-di-GMP phosphodiesterase A-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 685; Mature: 684

Protein sequence:

>685_residues
MTKFRKIHSLAFKQAKSVFLVSVLLGLCFSFYHTLSDLHQEQSKVQEHYNFKLVQSYENASQAAYHLNNLLAEQVATTLM
LDPGIFKVEIVDDFGDVMTRKEKAISEQSQLVSVLASYLTPAVSVFSAELHQPNSNVVVGKLSFYIDGSSIAKVFIAKTT
RVLLFDLLRNTLLTTILLLFFYQKLSRPITMLITWVNSLNDTQRSPLPLRLTHDDELSELASTFQSMWKGKELAESKLNQ
LAYYDSLTGLANRSLLLQKLSDAIETAQNSHSTGVLFYLDLDRFKTINDSLGHTIGDQLIKAVALRMEAWTKNDYLSARI
GGDEFAVLIPYLSPAKAEEVAKQLLTLISNPYAVDDHQFYCTVSIGISVFPSVGSCNIDVLRQADTALYRAKASGRNKFM
FYEPEMQAQVESFLEIEKGLHEALNQRQLELFYQPQVDEQHNIIGVEALIRWNHPKRGLLPPGVFMPIAEETGQILPIGN
WIIEQACYQYAQWKKQGILPPHFRRLAINISPLQFAQESFIEQVNHALRQAGITGEPIELEITESLLLENVESAIEKMAK
LKESQISISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVNQLHLDDNDQAIVDTILAIARKLNLEVIAEGVEDTSELAALK
KLGCNQFQGYLFDKPLRAEEIAQRFVSNSYRKIQTLPVATNSLQK

Sequences:

>Translated_685_residues
MTKFRKIHSLAFKQAKSVFLVSVLLGLCFSFYHTLSDLHQEQSKVQEHYNFKLVQSYENASQAAYHLNNLLAEQVATTLM
LDPGIFKVEIVDDFGDVMTRKEKAISEQSQLVSVLASYLTPAVSVFSAELHQPNSNVVVGKLSFYIDGSSIAKVFIAKTT
RVLLFDLLRNTLLTTILLLFFYQKLSRPITMLITWVNSLNDTQRSPLPLRLTHDDELSELASTFQSMWKGKELAESKLNQ
LAYYDSLTGLANRSLLLQKLSDAIETAQNSHSTGVLFYLDLDRFKTINDSLGHTIGDQLIKAVALRMEAWTKNDYLSARI
GGDEFAVLIPYLSPAKAEEVAKQLLTLISNPYAVDDHQFYCTVSIGISVFPSVGSCNIDVLRQADTALYRAKASGRNKFM
FYEPEMQAQVESFLEIEKGLHEALNQRQLELFYQPQVDEQHNIIGVEALIRWNHPKRGLLPPGVFMPIAEETGQILPIGN
WIIEQACYQYAQWKKQGILPPHFRRLAINISPLQFAQESFIEQVNHALRQAGITGEPIELEITESLLLENVESAIEKMAK
LKESQISISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVNQLHLDDNDQAIVDTILAIARKLNLEVIAEGVEDTSELAALK
KLGCNQFQGYLFDKPLRAEEIAQRFVSNSYRKIQTLPVATNSLQK
>Mature_684_residues
TKFRKIHSLAFKQAKSVFLVSVLLGLCFSFYHTLSDLHQEQSKVQEHYNFKLVQSYENASQAAYHLNNLLAEQVATTLML
DPGIFKVEIVDDFGDVMTRKEKAISEQSQLVSVLASYLTPAVSVFSAELHQPNSNVVVGKLSFYIDGSSIAKVFIAKTTR
VLLFDLLRNTLLTTILLLFFYQKLSRPITMLITWVNSLNDTQRSPLPLRLTHDDELSELASTFQSMWKGKELAESKLNQL
AYYDSLTGLANRSLLLQKLSDAIETAQNSHSTGVLFYLDLDRFKTINDSLGHTIGDQLIKAVALRMEAWTKNDYLSARIG
GDEFAVLIPYLSPAKAEEVAKQLLTLISNPYAVDDHQFYCTVSIGISVFPSVGSCNIDVLRQADTALYRAKASGRNKFMF
YEPEMQAQVESFLEIEKGLHEALNQRQLELFYQPQVDEQHNIIGVEALIRWNHPKRGLLPPGVFMPIAEETGQILPIGNW
IIEQACYQYAQWKKQGILPPHFRRLAINISPLQFAQESFIEQVNHALRQAGITGEPIELEITESLLLENVESAIEKMAKL
KESQISISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVNQLHLDDNDQAIVDTILAIARKLNLEVIAEGVEDTSELAALKK
LGCNQFQGYLFDKPLRAEEIAQRFVSNSYRKIQTLPVATNSLQK

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=425, Percent_Identity=40.2352941176471, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=35.6481481481481, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI226510982, Length=457, Percent_Identity=28.0087527352298, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI87081980, Length=248, Percent_Identity=33.8709677419355, Blast_Score=146, Evalue=5e-36,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=34.9397590361446, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI87081845, Length=258, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=32.9411764705882, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787055, Length=261, Percent_Identity=33.7164750957854, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=31.8367346938775, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788849, Length=250, Percent_Identity=33.6, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI87081743, Length=242, Percent_Identity=32.2314049586777, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788381, Length=190, Percent_Identity=33.6842105263158, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87082096, Length=244, Percent_Identity=29.5081967213115, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=34.5238095238095, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=29.0123456790123, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=30.5389221556886, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=33.9181286549708, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=30.2325581395349, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=31.25, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=31.6770186335404, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI145693134, Length=183, Percent_Identity=29.5081967213115, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=31.1377245508982, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789650, Length=441, Percent_Identity=20.8616780045351, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77292; Mature: 77160

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFRKIHSLAFKQAKSVFLVSVLLGLCFSFYHTLSDLHQEQSKVQEHYNFKLVQSYENA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SQAAYHLNNLLAEQVATTLMLDPGIFKVEIVDDFGDVMTRKEKAISEQSQLVSVLASYLT
HHHHHHHHHHHHHHHHHHHEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAVSVFSAELHQPNSNVVVGKLSFYIDGSSIAKVFIAKTTRVLLFDLLRNTLLTTILLLF
HHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYQKLSRPITMLITWVNSLNDTQRSPLPLRLTHDDELSELASTFQSMWKGKELAESKLNQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
LAYYDSLTGLANRSLLLQKLSDAIETAQNSHSTGVLFYLDLDRFKTINDSLGHTIGDQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
KAVALRMEAWTKNDYLSARIGGDEFAVLIPYLSPAKAEEVAKQLLTLISNPYAVDDHQFY
HHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCEEE
CTVSIGISVFPSVGSCNIDVLRQADTALYRAKASGRNKFMFYEPEMQAQVESFLEIEKGL
EEEEECCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHH
HEALNQRQLELFYQPQVDEQHNIIGVEALIRWNHPKRGLLPPGVFMPIAEETGQILPIGN
HHHHCCHHEEEEECCCCCCCCCEEEEEHHEEECCCCCCCCCCCCEECCHHCCCCEEECHH
WIIEQACYQYAQWKKQGILPPHFRRLAINISPLQFAQESFIEQVNHALRQAGITGEPIEL
HHHHHHHHHHHHHHHCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
EITESLLLENVESAIEKMAKLKESQISISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVNQ
EHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHLDDNDQAIVDTILAIARKLNLEVIAEGVEDTSELAALKKLGCNQFQGYLFDKPLRAEE
HCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCCCCHHH
IAQRFVSNSYRKIQTLPVATNSLQK
HHHHHHHCCHHHEEEECCCHHCCCC
>Mature Secondary Structure 
TKFRKIHSLAFKQAKSVFLVSVLLGLCFSFYHTLSDLHQEQSKVQEHYNFKLVQSYENA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SQAAYHLNNLLAEQVATTLMLDPGIFKVEIVDDFGDVMTRKEKAISEQSQLVSVLASYLT
HHHHHHHHHHHHHHHHHHHEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PAVSVFSAELHQPNSNVVVGKLSFYIDGSSIAKVFIAKTTRVLLFDLLRNTLLTTILLLF
HHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYQKLSRPITMLITWVNSLNDTQRSPLPLRLTHDDELSELASTFQSMWKGKELAESKLNQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
LAYYDSLTGLANRSLLLQKLSDAIETAQNSHSTGVLFYLDLDRFKTINDSLGHTIGDQLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
KAVALRMEAWTKNDYLSARIGGDEFAVLIPYLSPAKAEEVAKQLLTLISNPYAVDDHQFY
HHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEECCCEEE
CTVSIGISVFPSVGSCNIDVLRQADTALYRAKASGRNKFMFYEPEMQAQVESFLEIEKGL
EEEEECCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHH
HEALNQRQLELFYQPQVDEQHNIIGVEALIRWNHPKRGLLPPGVFMPIAEETGQILPIGN
HHHHCCHHEEEEECCCCCCCCCEEEEEHHEEECCCCCCCCCCCCEECCHHCCCCEEECHH
WIIEQACYQYAQWKKQGILPPHFRRLAINISPLQFAQESFIEQVNHALRQAGITGEPIEL
HHHHHHHHHHHHHHHCCCCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
EITESLLLENVESAIEKMAKLKESQISISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVNQ
EHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHLDDNDQAIVDTILAIARKLNLEVIAEGVEDTSELAALKKLGCNQFQGYLFDKPLRAEE
HCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCCCCHHH
IAQRFVSNSYRKIQTLPVATNSLQK
HHHHHHHCCHHHEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]