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The map label for this gene is tldD [H]

Identifier: 227080633

GI number: 227080633

Start: 436126

End: 437571

Strand: Direct

Name: tldD [H]

Synonym: VCM66_0407

Alternate gene names: 227080633

Gene position: 436126-437571 (Clockwise)

Preceding gene: 227080632

Following gene: 227080635

Centisome position: 15.08

GC content: 51.38

Gene sequence:

>1446_bases
ATGACGATGAACCAAATTGAAACGGCACTGCTGGCACCCGCTGGGCTCACTGAACAGGATATTGCCGATACGCTGTCCAG
TATTGCGACTCGCCAGATTGATTATGCCGATATTTATTTCCAATCCAGCTGGCATGAATCTCTAGTGCTGGAAGACAGCA
TCATTAAAGACGGCTCATTCAATATTGATTGTGGGGTCGGTGTGCGCGCCGTCAGTGGTGAAAAAACCGGTTTTGCTTAT
TCCGACCAAATTCAGTTAGAAGGTTTAAAGCAGAGTGCCATCGCGGCGCGTGGGATTGCTCAACAAGGCCAAAACCTCAC
CGTACAAGCGTTTAAGCGCGCGCAACATCCTGCGTTTTATGGCGCGCATAACCCACTGGAAAGTTGGGAAAAACAGCAAA
AAACCGAACTGCTGAAACAACTGGATGCGTACATTCGTACTAAAGAGCCTCTCATTACCGAAGTGTCAGTCAGTCTAAGT
GGTGTGCATGAGCAGATCCTCGTGGCGGCTACCGATGGCACGTACGCAGGGGATATTCGTCCTCTGGTTCGTCTTTCGAT
CAGTGTGTTGGCGCAAAAAGGCGATCGCCGTGAGCGCGGTAGCGCCGGTGGTGGTGGCCGTTTTGGTTACGACTATTTCT
TACAAGAAGAAGCGGGACAAAAAATCGCGTTTTCTTTCGCCGATGAAGCGATTCGTCAAGCGCTCGTTAACCTTGAAGCG
GTAGCCGCTCCTGCCGGAACCATGCCTGTGGTACTCGGTTCTGGTTGGCCGGGTGTGTTGCTGCATGAGGCGGTGGGTCA
TGGCCTGGAAGGCGATTTTAACCGTAAAGGCTCGTCGGTATTTGCAGGCAAAGTCGGCAAAAAAGTCACTTCCGATCTGT
GTACGATTGTCGATGACGGTACACTCAAAGATCTGCGCGGCTCTCTCAACGTTGATGATGAAGGGGTAAGTGGTCAATAC
AACGTGCTGATCGAAAAAGGTATTTTGAAAGGCTACATCCAAGACAAGCTCAATGCTCGTTTAATGGGCGTGGCACCAAC
GGGTAACGGACGCCGTGAATCTTACGCTCATCTGCCGATGCCGCGTATGACCAATACTTACATGCTACCGGGCGAGCACA
CACCAGAAGAGATCATCGCTTCGGTGAAAAAAGGCATTTACGCGCCGAACTTTGGTGGCGGTCAGGTCGATATCACCTCC
GGTAAGTTTGTGTTCTCGGCCTCTGAAGCTTACTTGATTGAAAATGGCAAAATCACCCGTCCAATCAAAGGCGCAACTCT
GATTGGTTCTGGTATTGAAGCCATGCAGCAGGTATCTATGGTCGGTAACGATCTGGCGCTGGATCGTGGTGTTGGCGTGT
GTGGTAAAGCCGGACAAAGCGTGCCTGTGGGCGTTGGCCAGCCAACTCTGAAGTTGGATGCCCTGACCGTGGGTGGGACA
GAGTAA

Upstream 100 bases:

>100_bases
TGGTCGAGTTCGATCTTGCAACGCTCGATTCTGTGAGACGCGCAATGCCCATTACACAGCACACGCGTTTTACCCATCAA
TTAATAGAGAACACACACTG

Downstream 100 bases:

>100_bases
CCGAATTTTGCTGGTTCGTTGGCCTAACCGTTAGTCTGACAATAGACACTACGACACAAAACCACCGCCATTCGCGGTGG
TTTTGCGTTGAGAGTTTAAA

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTMNQIETALLAPAGLTEQDIADTLSSIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY
SDQIQLEGLKQSAIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESWEKQQKTELLKQLDAYIRTKEPLITEVSVSLS
GVHEQILVAATDGTYAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDYFLQEEAGQKIAFSFADEAIRQALVNLEA
VAAPAGTMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQY
NVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
E

Sequences:

>Translated_481_residues
MTMNQIETALLAPAGLTEQDIADTLSSIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY
SDQIQLEGLKQSAIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESWEKQQKTELLKQLDAYIRTKEPLITEVSVSLS
GVHEQILVAATDGTYAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDYFLQEEAGQKIAFSFADEAIRQALVNLEA
VAAPAGTMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQY
NVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
E
>Mature_480_residues
TMNQIETALLAPAGLTEQDIADTLSSIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAYS
DQIQLEGLKQSAIAARGIAQQGQNLTVQAFKRAQHPAFYGAHNPLESWEKQQKTELLKQLDAYIRTKEPLITEVSVSLSG
VHEQILVAATDGTYAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDYFLQEEAGQKIAFSFADEAIRQALVNLEAV
AAPAGTMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDGTLKDLRGSLNVDDEGVSGQYN
VLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITSG
KFVFSASEAYLIENGKITRPIKGATLIGSGIEAMQQVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGTE

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=480, Percent_Identity=68.5416666666667, Blast_Score=655, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51205; Mature: 51073

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMNQIETALLAPAGLTEQDIADTLSSIATRQIDYADIYFQSSWHESLVLEDSIIKDGSF
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEHHHCCCCCC
NIDCGVGVRAVSGEKTGFAYSDQIQLEGLKQSAIAARGIAQQGQNLTVQAFKRAQHPAFY
EEECCCCEEEECCCCCCCEECCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEE
GAHNPLESWEKQQKTELLKQLDAYIRTKEPLITEVSVSLSGVHEQILVAATDGTYAGDIR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCEEEEEEECCCCCCCCCH
PLVRLSISVLAQKGDRRERGSAGGGGRFGYDYFLQEEAGQKIAFSFADEAIRQALVNLEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDG
HCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCC
TLKDLRGSLNVDDEGVSGQYNVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPM
CHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITR
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PIKGATLIGSGIEAMQQVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
CCCCCEEECHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C
>Mature Secondary Structure 
TMNQIETALLAPAGLTEQDIADTLSSIATRQIDYADIYFQSSWHESLVLEDSIIKDGSF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEHHHCCCCCC
NIDCGVGVRAVSGEKTGFAYSDQIQLEGLKQSAIAARGIAQQGQNLTVQAFKRAQHPAFY
EEECCCCEEEECCCCCCCEECCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEE
GAHNPLESWEKQQKTELLKQLDAYIRTKEPLITEVSVSLSGVHEQILVAATDGTYAGDIR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCEEEEEEECCCCCCCCCH
PLVRLSISVLAQKGDRRERGSAGGGGRFGYDYFLQEEAGQKIAFSFADEAIRQALVNLEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGSSVFAGKVGKKVTSDLCTIVDDG
HCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCC
TLKDLRGSLNVDDEGVSGQYNVLIEKGILKGYIQDKLNARLMGVAPTGNGRRESYAHLPM
CHHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTYMLPGEHTPEEIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITR
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PIKGATLIGSGIEAMQQVSMVGNDLALDRGVGVCGKAGQSVPVGVGQPTLKLDALTVGGT
CCCCCEEECHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]