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The map label for this gene is yafV [C]

Identifier: 227080632

GI number: 227080632

Start: 435299

End: 436126

Strand: Direct

Name: yafV [C]

Synonym: VCM66_0406

Alternate gene names: 227080632

Gene position: 435299-436126 (Clockwise)

Preceding gene: 227080631

Following gene: 227080633

Centisome position: 15.05

GC content: 52.17

Gene sequence:

>828_bases
ATGCAACGAGTTGGACTGGTGCAAATGACCTCAGGCCCTGAGATAAGTCGTAATCTGACTTATCTCAAACAAGAGGTGGC
CAAGCTTGCTCAGCAAGGAGCACAATGGATTGTGACACCAGAAAATGCCCTGCTGTTGGGGAATCGTGAACAATACCATC
AACAAGCCGAATCACTGGATCACGGCCCAGTTCAGCACGCCTTAGCGAGCCTCGCCAAAGAATATGGTGTATGGTTATTG
ATAGGCAGTATGCCGATCCGCCACGCTGAGGGGGTTACTACCAGTAGCCTATTGTGGAATGCACAAGGTGAGCGAGTGGC
GGTTTACGATAAACTGCATATGTTCGATGTCGATGTCGCTGATGGCCATCAGCGTTATCGCGAATCGGAAACCTTTACGC
CGGGGCAACAGGTGGTCGTCACCTCAACGCCGTTTGGAGCGTTGGGCCTATCGATTTGCTACGATGTGCGTTTTCCGCAC
TTGTACGCAGATTTACGGCGCCAAGGTGCACAGATTTTGCTGGTTCCTGCGGCCTTTACTGCGGTGACGGGCCAAGCCCA
CTGGGAAGTCTTATTACGCGCCCGAGCCATTGAAACGCAATGCTGGGTGATTGCCGTGGGTCAAACTGGACATCACCCAT
GCGGACGAGAGACGTGGGGACATTCCATGGTGATTAGCCCGTGGGGTGAAGTGATCGCCAATTTAGGCGCCGAAGTACAA
AGTAAAGTGGTCGAGTTCGATCTTGCAACGCTCGATTCTGTGAGACGCGCAATGCCCATTACACAGCACACGCGTTTTAC
CCATCAATTAATAGAGAACACACACTGA

Upstream 100 bases:

>100_bases
AAGGACCGCTCGATTCACCGACAGTGAAAGAGCTTTCGCGCAGTAAAGGCGAATTCAAGTTGCCGGAAAAGCTGCGTAAA
CTGACTGAATAGGGAAGAAA

Downstream 100 bases:

>100_bases
TGACGATGAACCAAATTGAAACGGCACTGCTGGCACCCGCTGGGCTCACTGAACAGGATATTGCCGATACGCTGTCCAGT
ATTGCGACTCGCCAGATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MQRVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYHQQAESLDHGPVQHALASLAKEYGVWLL
IGSMPIRHAEGVTTSSLLWNAQGERVAVYDKLHMFDVDVADGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPH
LYADLRRQGAQILLVPAAFTAVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAEVQ
SKVVEFDLATLDSVRRAMPITQHTRFTHQLIENTH

Sequences:

>Translated_275_residues
MQRVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYHQQAESLDHGPVQHALASLAKEYGVWLL
IGSMPIRHAEGVTTSSLLWNAQGERVAVYDKLHMFDVDVADGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPH
LYADLRRQGAQILLVPAAFTAVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAEVQ
SKVVEFDLATLDSVRRAMPITQHTRFTHQLIENTH
>Mature_275_residues
MQRVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYHQQAESLDHGPVQHALASLAKEYGVWLL
IGSMPIRHAEGVTTSSLLWNAQGERVAVYDKLHMFDVDVADGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPH
LYADLRRQGAQILLVPAAFTAVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAEVQ
SKVVEFDLATLDSVRRAMPITQHTRFTHQLIENTH

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=37.3134328358209, Blast_Score=173, Evalue=1e-43,
Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=37.3134328358209, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=37.3134328358209, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI9910460, Length=263, Percent_Identity=33.0798479087452, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=32.8125, Blast_Score=100, Evalue=1e-21,
Organism=Escherichia coli, GI1786412, Length=208, Percent_Identity=31.25, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=270, Percent_Identity=37.4074074074074, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322335, Length=299, Percent_Identity=32.4414715719064, Blast_Score=162, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6323383, Length=274, Percent_Identity=30.6569343065693, Blast_Score=152, Evalue=6e-38,
Organism=Drosophila melanogaster, GI17933642, Length=265, Percent_Identity=41.5094339622642, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI21355835, Length=268, Percent_Identity=26.4925373134328, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30630; Mature: 30630

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYHQQAESLD
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCHHHHHHHHHHCC
HGPVQHALASLAKEYGVWLLIGSMPIRHAEGVTTSSLLWNAQGERVAVYDKLHMFDVDVA
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHEEECCCCCEEEEEEEEEEEEEECC
DGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPHLYADLRRQGAQILLVPAAFT
CCHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECHHH
AVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAEVQ
HHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHCHHHH
SKVVEFDLATLDSVRRAMPITQHTRFTHQLIENTH
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYHQQAESLD
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEECCHHHHHHHHHHCC
HGPVQHALASLAKEYGVWLLIGSMPIRHAEGVTTSSLLWNAQGERVAVYDKLHMFDVDVA
CCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHEEECCCCCEEEEEEEEEEEEEECC
DGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPHLYADLRRQGAQILLVPAAFT
CCHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHEECCCHHHHHHHHHCCCEEEEEECHHH
AVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAEVQ
HHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEECCHHHHHHHHCHHHH
SKVVEFDLATLDSVRRAMPITQHTRFTHQLIENTH
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]