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The map label for this gene is ubiC [H]

Identifier: 227080331

GI number: 227080331

Start: 94284

End: 94835

Strand: Reverse

Name: ubiC [H]

Synonym: VCM66_0095

Alternate gene names: 227080331

Gene position: 94835-94284 (Counterclockwise)

Preceding gene: 227080332

Following gene: 227080330

Centisome position: 3.28

GC content: 46.74

Gene sequence:

>552_bases
TTGAATAATAGTATGAATCAATTAACTTCGCTCTATTTAGCCGCACTGAATCGCGTCACTTGGCAACAGCCTGATGACAT
TGAATTTCCAGCCCCTTTAGCTCAGCAATGGCTACTCGAACAAGGCTCTCTTTCGCGCCGAATGGCGACGCAGTGTGAGC
ATCTGACCGTAGATTTATTAAGTAACCAAATCATGCTGGCGGACACCCTGAGCTATGATGAAACTCAACTGCTCGCCTCT
GAAGAGTATCTTCTACGCCAAGTGATTATTTATGGCGACCAACAACCTTGGGTATTTGGCCATACTTTGATCCCTCGCTC
ATCCATGCACAATCAGCCGTTTGATTTCACCCAACAAGGGAAAATTCCACTAGGTCTCACCGTATTTAGTGCGGATAATG
TTAAGCGAGATGCACTGCAAGTTGGCTGGGTAGAGACAGAACTCGGACGACTATTAGCCCGTCGCTCTCGCTTATGGATG
AACAACAAACCCATGTTAGTGACGGAGCTGTTTCTCGCCACATCCCCGATTTACTCTAAGGAGAGAGTGTAA

Upstream 100 bases:

>100_bases
GCGTTCGAACTCTTTGGTTTGGAATCAAAATCTGAGCTTTATTGTATACCCAAACTCGGTGGTATTGCAGGTAGCTAGGG
TAATCGGGTAAAGCGTCAAA

Downstream 100 bases:

>100_bases
ATGACCGCTGTAAAAGCGCGCGCTTACTGGCAACTGATGCGCATGGATCGCCCGATTGGCTCCCTACTCTTACTTTGGCC
TACTCTGTGGGCGCTGCTTT

Product: chorismate-pyruvate lyase

Products: NA

Alternate protein names: CL; CPL [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MNNSMNQLTSLYLAALNRVTWQQPDDIEFPAPLAQQWLLEQGSLSRRMATQCEHLTVDLLSNQIMLADTLSYDETQLLAS
EEYLLRQVIIYGDQQPWVFGHTLIPRSSMHNQPFDFTQQGKIPLGLTVFSADNVKRDALQVGWVETELGRLLARRSRLWM
NNKPMLVTELFLATSPIYSKERV

Sequences:

>Translated_183_residues
MNNSMNQLTSLYLAALNRVTWQQPDDIEFPAPLAQQWLLEQGSLSRRMATQCEHLTVDLLSNQIMLADTLSYDETQLLAS
EEYLLRQVIIYGDQQPWVFGHTLIPRSSMHNQPFDFTQQGKIPLGLTVFSADNVKRDALQVGWVETELGRLLARRSRLWM
NNKPMLVTELFLATSPIYSKERV
>Mature_183_residues
MNNSMNQLTSLYLAALNRVTWQQPDDIEFPAPLAQQWLLEQGSLSRRMATQCEHLTVDLLSNQIMLADTLSYDETQLLAS
EEYLLRQVIIYGDQQPWVFGHTLIPRSSMHNQPFDFTQQGKIPLGLTVFSADNVKRDALQVGWVETELGRLLARRSRLWM
NNKPMLVTELFLATSPIYSKERV

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway [H]

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family [H]

Homologues:

Organism=Escherichia coli, GI87082361, Length=153, Percent_Identity=32.0261437908497, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007440 [H]

Pfam domain/function: PF04345 Chor_lyase [H]

EC number: =4.1.3.40 [H]

Molecular weight: Translated: 21068; Mature: 21068

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSMNQLTSLYLAALNRVTWQQPDDIEFPAPLAQQWLLEQGSLSRRMATQCEHLTVDLL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SNQIMLADTLSYDETQLLASEEYLLRQVIIYGDQQPWVFGHTLIPRSSMHNQPFDFTQQG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
KIPLGLTVFSADNVKRDALQVGWVETELGRLLARRSRLWMNNKPMLVTELFLATSPIYSK
CCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
ERV
CCC
>Mature Secondary Structure
MNNSMNQLTSLYLAALNRVTWQQPDDIEFPAPLAQQWLLEQGSLSRRMATQCEHLTVDLL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
SNQIMLADTLSYDETQLLASEEYLLRQVIIYGDQQPWVFGHTLIPRSSMHNQPFDFTQQG
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCC
KIPLGLTVFSADNVKRDALQVGWVETELGRLLARRSRLWMNNKPMLVTELFLATSPIYSK
CCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
ERV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]