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The map label for this gene is ubiA

Identifier: 227080330

GI number: 227080330

Start: 93429

End: 94283

Strand: Reverse

Name: ubiA

Synonym: VCM66_0094

Alternate gene names: 227080330

Gene position: 94283-93429 (Counterclockwise)

Preceding gene: 227080331

Following gene: 227080328

Centisome position: 3.26

GC content: 49.59

Gene sequence:

>855_bases
ATGACCGCTGTAAAAGCGCGCGCTTACTGGCAACTGATGCGCATGGATCGCCCGATTGGCTCCCTACTCTTACTTTGGCC
TACTCTGTGGGCGCTGCTTTTAGCCGCTCAAGGCTTGCCGGATCTTCGCGTCTTAGTCGTGTTTGTGTTAGGGGTTTTTT
TAATGCGCTCGGCTGGGTGTGTGATCAACGATTACGCCGACCGCCATGTCGATGGCCATGTGAAGCGCACGAGCCAACGT
CCATTGCCCGCAGGGTTAGTTTCGGCCAAAGAAGCCTTACTGTTATTTGTTCTTCTTGCTGTCAGCTCGTTCTTACTCGT
GTTGACTATGAATACCCTAACTATCCAGCTCTCTTTTATCGGTATTCTGTTAGCCTTTGTTTACCCGTTTATGAAGCGCT
TCACTCACCTGCCTCAACTGGTGCTTGGCCTCGCGTTCAGTTGGTCGATTCCTATGGCTTGGGCTGCTCAAGCAAATACG
CTGACTCCACAAGTCTGGGTACTGTTTTTGATTAATGCGTTATGGACGATTGCTTACGACACTCAATACGCCATGGTCGA
CCGAGATGATGATGTGAAAATTGGCATCAAATCGACCGCGATCTTATTCGGGCGTTGGGATAAACGCATCATTGGCCTAC
TGCAATTGGCCACTTTGAGTTTACTGGTCGCTCTAGGCCAAGGTTTAGCGCTTGGCACCAGTTACTACTGGGGTCTACTG
ATCGCAGCGGGGCTGTTTGCTTACCAACAACATTTGATCCGTTATCGCGAACGTATGCCTTGTTTTCAGGCGTTTTTAAA
TAACAACTATGTAGGAATGGCCATCACCGCAGGCATTCTGCTCAGCGTTTGGTAA

Upstream 100 bases:

>100_bases
ATTAGCCCGTCGCTCTCGCTTATGGATGAACAACAAACCCATGTTAGTGACGGAGCTGTTTCTCGCCACATCCCCGATTT
ACTCTAAGGAGAGAGTGTAA

Downstream 100 bases:

>100_bases
TCCCAGCTTAAGGCAAAAGAAAAGGCATCCGCAGGATGCCTTTTTCATTCGGTTCGATTGGCTAGAACACAATCGTTACG
CGTCAACCTGACACAAGCTT

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTAVKARAYWQLMRMDRPIGSLLLLWPTLWALLLAAQGLPDLRVLVVFVLGVFLMRSAGCVINDYADRHVDGHVKRTSQR
PLPAGLVSAKEALLLFVLLAVSSFLLVLTMNTLTIQLSFIGILLAFVYPFMKRFTHLPQLVLGLAFSWSIPMAWAAQANT
LTPQVWVLFLINALWTIAYDTQYAMVDRDDDVKIGIKSTAILFGRWDKRIIGLLQLATLSLLVALGQGLALGTSYYWGLL
IAAGLFAYQQHLIRYRERMPCFQAFLNNNYVGMAITAGILLSVW

Sequences:

>Translated_284_residues
MTAVKARAYWQLMRMDRPIGSLLLLWPTLWALLLAAQGLPDLRVLVVFVLGVFLMRSAGCVINDYADRHVDGHVKRTSQR
PLPAGLVSAKEALLLFVLLAVSSFLLVLTMNTLTIQLSFIGILLAFVYPFMKRFTHLPQLVLGLAFSWSIPMAWAAQANT
LTPQVWVLFLINALWTIAYDTQYAMVDRDDDVKIGIKSTAILFGRWDKRIIGLLQLATLSLLVALGQGLALGTSYYWGLL
IAAGLFAYQQHLIRYRERMPCFQAFLNNNYVGMAITAGILLSVW
>Mature_283_residues
TAVKARAYWQLMRMDRPIGSLLLLWPTLWALLLAAQGLPDLRVLVVFVLGVFLMRSAGCVINDYADRHVDGHVKRTSQRP
LPAGLVSAKEALLLFVLLAVSSFLLVLTMNTLTIQLSFIGILLAFVYPFMKRFTHLPQLVLGLAFSWSIPMAWAAQANTL
TPQVWVLFLINALWTIAYDTQYAMVDRDDDVKIGIKSTAILFGRWDKRIIGLLQLATLSLLVALGQGLALGTSYYWGLLI
AAGLFAYQQHLIRYRERMPCFQAFLNNNYVGMAITAGILLSVW

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=35.1254480286738, Blast_Score=166, Evalue=2e-41,
Organism=Escherichia coli, GI1790473, Length=284, Percent_Identity=62.3239436619718, Blast_Score=353, Evalue=5e-99,
Organism=Escherichia coli, GI1786631, Length=187, Percent_Identity=26.7379679144385, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553718, Length=280, Percent_Identity=36.7857142857143, Blast_Score=170, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32565247, Length=280, Percent_Identity=35.7142857142857, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17553720, Length=181, Percent_Identity=40.8839779005525, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=139, Percent_Identity=44.6043165467626, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=138, Percent_Identity=44.2028985507246, Blast_Score=107, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324370, Length=251, Percent_Identity=35.4581673306773, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355567, Length=281, Percent_Identity=37.0106761565836, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIA_VIBC3 (A5F4H4)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- STRING:   A5F4H4
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2421
- eggNOG:   COG0382
- HOGENOM:   HBG324383
- OMA:   YHYTLIR
- ProtClustDB:   PRK12848
- BioCyc:   VCHO345073:VC0395_A2421-MONOMER
- HAMAP:   MF_01635
- InterPro:   IPR006370
- InterPro:   IPR000537
- TIGRFAMs:   TIGR01474

Pfam domain/function: PF01040 UbiA

EC number: 2.5.1.-

Molecular weight: Translated: 31821; Mature: 31689

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x23f5f614)-; HASH(0x24451aec)-; HASH(0x244624c8)-; HASH(0x2448319c)-; HASH(0x2460fc1c)-; HASH(0x24490fd0)-; HASH(0x2460fbb0)-; HASH(0x2441f6e8)-; HASH(0x244ac4d8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVKARAYWQLMRMDRPIGSLLLLWPTLWALLLAAQGLPDLRVLVVFVLGVFLMRSAGC
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
VINDYADRHVDGHVKRTSQRPLPAGLVSAKEALLLFVLLAVSSFLLVLTMNTLTIQLSFI
EEECHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILLAFVYPFMKRFTHLPQLVLGLAFSWSIPMAWAAQANTLTPQVWVLFLINALWTIAYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
TQYAMVDRDDDVKIGIKSTAILFGRWDKRIIGLLQLATLSLLVALGQGLALGTSYYWGLL
CEEEEECCCCCCEEEEEHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAAGLFAYQQHLIRYRERMPCFQAFLNNNYVGMAITAGILLSVW
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHCH
>Mature Secondary Structure 
TAVKARAYWQLMRMDRPIGSLLLLWPTLWALLLAAQGLPDLRVLVVFVLGVFLMRSAGC
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
VINDYADRHVDGHVKRTSQRPLPAGLVSAKEALLLFVLLAVSSFLLVLTMNTLTIQLSFI
EEECHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILLAFVYPFMKRFTHLPQLVLGLAFSWSIPMAWAAQANTLTPQVWVLFLINALWTIAYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
TQYAMVDRDDDVKIGIKSTAILFGRWDKRIIGLLQLATLSLLVALGQGLALGTSYYWGLL
CEEEEECCCCCCEEEEEHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IAAGLFAYQQHLIRYRERMPCFQAFLNNNYVGMAITAGILLSVW
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA