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The map label for this gene is avtA [H]

Identifier: 227080256

GI number: 227080256

Start: 15294

End: 16550

Strand: Reverse

Name: avtA [H]

Synonym: VCM66_0019

Alternate gene names: 227080256

Gene position: 16550-15294 (Counterclockwise)

Preceding gene: 227080257

Following gene: 227080247

Centisome position: 0.57

GC content: 49.88

Gene sequence:

>1257_bases
ATGCAGTATTCCTCTTTTGGCGAAAAGTTTAATCGCTACTCCGGTATTACCCAGTTAATGGATGATTTGAACGATGGTCT
GCGCACTCCAGGCGCGATCATGCTTGGTGGCGGTAATCCTGCTGCCATCCCTGCCATGCTCGATTATTTCCATAACACCA
GCGCCGAAATGTTGGCCGATGGTTCACTGCTCAATGCCATGACCAATTACGATGGTCCACAGGGCAAAGATGTGTTTGTA
AAATCGCTCGCTACACTGCTGCGTGAGACGTATGGCTGGAATATCAGCGAAAAGAACATCACCTTGACCAACGGCAGCCA
GAGTGGCTTTTTCTACCTGTTTAACTTGTTTGCCGGTAAACAGCCCGATGGTGCACACAAAAAAATCCTCCTACCCCTCG
CGCCCGAATACATTGGCTACGGTGATGCTGGCATTGATGACGATATTTTTGTCTCCTACCGTCCGGAGATTGAGCTGCTC
GATCAAGGACTGTTCAAATACCATGTGGACTTTTCTGAGCTGAAAGTCGATGAATCGGTGGCCGCGATCTGTGTGTCTCG
CCCCACCAACCCAACCGGTAACGTGTTAACCGAAGAGGAAATCCACAAACTCGACCAACTGGCACGTGATAACGGTGTGC
CGTTAATTATCGACAATGCTTACGGCGTGCCATTCCCGAATATCATTTTTGAAGACATTGAACCGTTTTGGAATGACAAC
ACCATCTTGTGCATGAGCCTATCCAAACTGGGCTTGCCCGGTCTGCGCTGCGGCATTGTGATCGCCAATGAAGCGGTAAC
TCAAGCGCTGACCAACATGAATGGCATCATTAGCTTAGCACCCGGCAGTATGGGACCCGCACTGGTGCAACGCATGATAG
AAAAAGGCGATCTGCTGAGACTTAGCGAGCAGGTGATCAAGCCGTTTTATCGCCAAAAAGCGCAACATGCGGTAGAGCTG
CTGCAAAGTGCGATTACGGATCCGCGTTTTCGCATCCATAAACCCGAAGGGGCGATCTTCCTCTGGCTGTGGTTTGATGA
ACTGCCGATCACCACAATGGAGCTTTACCAACGTTTGAAAGCGCGTGGGGTATTGATTGTACCGGGCGAATATTTCTTTA
TCGGCCAGCCGCAAGAATGGCCACACGCTCATGAGTGCTTGCGTATGAACTATGTGCAGAACGAGCAAGCGATGGAACAA
GGCATTGCCATCATCGCCGAAGAAGTACAAAAAGCGTATCAACAAGCCAACGTCTAA

Upstream 100 bases:

>100_bases
CGCAAATACATTGCGGTATGTTCAAGAACTATTCTAAACGGCGGAGATTCCACCGGTATATCGTTTCGCAAACACACAGC
AATCATTAGGTAGTCGAGCA

Downstream 100 bases:

>100_bases
ACACCCAAACTAAGCAATGCAAAAAGCCCGCGAAATTCGCGGGCTTCGTTTTATCTCGCGTTCAGTGCGTTAAAACGCTG
CGCAGAGTTATTTGTTTTCC

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MQYSSFGEKFNRYSGITQLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFHNTSAEMLADGSLLNAMTNYDGPQGKDVFV
KSLATLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGKQPDGAHKKILLPLAPEYIGYGDAGIDDDIFVSYRPEIELL
DQGLFKYHVDFSELKVDESVAAICVSRPTNPTGNVLTEEEIHKLDQLARDNGVPLIIDNAYGVPFPNIIFEDIEPFWNDN
TILCMSLSKLGLPGLRCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLRLSEQVIKPFYRQKAQHAVEL
LQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLKARGVLIVPGEYFFIGQPQEWPHAHECLRMNYVQNEQAMEQ
GIAIIAEEVQKAYQQANV

Sequences:

>Translated_418_residues
MQYSSFGEKFNRYSGITQLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFHNTSAEMLADGSLLNAMTNYDGPQGKDVFV
KSLATLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGKQPDGAHKKILLPLAPEYIGYGDAGIDDDIFVSYRPEIELL
DQGLFKYHVDFSELKVDESVAAICVSRPTNPTGNVLTEEEIHKLDQLARDNGVPLIIDNAYGVPFPNIIFEDIEPFWNDN
TILCMSLSKLGLPGLRCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLRLSEQVIKPFYRQKAQHAVEL
LQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLKARGVLIVPGEYFFIGQPQEWPHAHECLRMNYVQNEQAMEQ
GIAIIAEEVQKAYQQANV
>Mature_418_residues
MQYSSFGEKFNRYSGITQLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFHNTSAEMLADGSLLNAMTNYDGPQGKDVFV
KSLATLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGKQPDGAHKKILLPLAPEYIGYGDAGIDDDIFVSYRPEIELL
DQGLFKYHVDFSELKVDESVAAICVSRPTNPTGNVLTEEEIHKLDQLARDNGVPLIIDNAYGVPFPNIIFEDIEPFWNDN
TILCMSLSKLGLPGLRCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLRLSEQVIKPFYRQKAQHAVEL
LQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLKARGVLIVPGEYFFIGQPQEWPHAHECLRMNYVQNEQAMEQ
GIAIIAEEVQKAYQQANV

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=417, Percent_Identity=63.0695443645084, Blast_Score=570, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46674; Mature: 46674

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYSSFGEKFNRYSGITQLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFHNTSAEMLAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHC
GSLLNAMTNYDGPQGKDVFVKSLATLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGK
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEHHCCC
QPDGAHKKILLPLAPEYIGYGDAGIDDDIFVSYRPEIELLDQGLFKYHVDFSELKVDESV
CCCCCCCEEEEEECHHHCCCCCCCCCCCEEEEECCCHHHHHCCHHHEECCHHHHHHHHHH
AAICVSRPTNPTGNVLTEEEIHKLDQLARDNGVPLIIDNAYGVPFPNIIFEDIEPFWNDN
HHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCHHCCCC
TILCMSLSKLGLPGLRCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLR
EEEEEEHHHCCCCCCEEEEEEEHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSEQVIKPFYRQKAQHAVELLQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQPQEWPHAHECLRMNYVQNEQAMEQGIAIIAEEVQKAYQQANV
HCCEEEECCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYSSFGEKFNRYSGITQLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFHNTSAEMLAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHHC
GSLLNAMTNYDGPQGKDVFVKSLATLLRETYGWNISEKNITLTNGSQSGFFYLFNLFAGK
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEHHCCC
QPDGAHKKILLPLAPEYIGYGDAGIDDDIFVSYRPEIELLDQGLFKYHVDFSELKVDESV
CCCCCCCEEEEEECHHHCCCCCCCCCCCEEEEECCCHHHHHCCHHHEECCHHHHHHHHHH
AAICVSRPTNPTGNVLTEEEIHKLDQLARDNGVPLIIDNAYGVPFPNIIFEDIEPFWNDN
HHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCHHCCCC
TILCMSLSKLGLPGLRCGIVIANEAVTQALTNMNGIISLAPGSMGPALVQRMIEKGDLLR
EEEEEEHHHCCCCCCEEEEEEEHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSEQVIKPFYRQKAQHAVELLQSAITDPRFRIHKPEGAIFLWLWFDELPITTMELYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQPQEWPHAHECLRMNYVQNEQAMEQGIAIIAEEVQKAYQQANV
HCCEEEECCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]