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The map label for this gene is patH [H]

Identifier: 227080247

GI number: 227080247

Start: 6354

End: 7100

Strand: Reverse

Name: patH [H]

Synonym: VCM66_0010

Alternate gene names: 227080247

Gene position: 7100-6354 (Counterclockwise)

Preceding gene: 227080256

Following gene: 227080246

Centisome position: 0.25

GC content: 47.52

Gene sequence:

>747_bases
ATGAAACACTGGTTTAACATCGCTCTGGCTGCCCTAGCCCTTTCTTCTGCCACCGTTCAGGCAGCTACCGAGGTGAAAGT
CGGCATGTCGGGCCGTTATTTCCCCTTCACCTTCGTGAAACAAGACGAGCTGCAAGGCTTTGAAGTGGATGTGTGGAATG
AAATTGGTAAACGTAATGATTATAAGGTCGAGTTTGTTACTGCGAACTTCTCCGGTTTGCTTGGCCTGCTCGAAACTGGG
CGCATCGACACCATTTCTAACCAAATCACTATCACAGATGCACGTAAGGCTAAATATCTATTCTCCGATCCGTATGTGAT
TGATGGTGCACAAATTACGGTGCGTAAAGGCAATGAAGCGATTAAAGGCATTGACGATTTAGCGGGCAAAACCGTTGCGG
TTAATTTAGGTTCTAACTTTGAACAGCTCCTGCGCAACCATGATAAAGACGGCAAAATCAACATCAAAACCTACGATACC
GGCATTGAACACGATGTGGCTTTAGGCCGTGCCGATGCGTTTGTGATGGATCGTCTGTCTGCGCTTGAGCTGATCGAAAA
GACCGGTTTACCACTGCAACTCGCGGGTTCACCGTTTGAAACTATCGAAAACGCGTGGCCATTTGTGAATAACGAAAAAG
GTCAGCAACTGCAAGGTGAAGTCAATAAAGCGCTCGCCGCCATGCGTGCTGACGGTACATTAAGCCAAATCGCGCTCAAA
TGGTTCGGTACCGATATCTCGCAATAA

Upstream 100 bases:

>100_bases
TTTTTGATTTTGATCAGTTATTGTTAATAACTACTGGTTATTTCTTTTAATGATTTAATTGCCAGTAGGATATAAACATA
AATTATACAGGAGTCACACA

Downstream 100 bases:

>100_bases
TTCTGCTTCACCAAGCTAGACTCTATTCTATAAAGGTGGGACTTTCCCACCTTTGATTATTTTAGGAAGGAAAGCAGATG
GGTTTTGACTTTCACTACAT

Product: amino acid ABC transporter, periplasmic amino acid-binding portion

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRNDYKVEFVTANFSGLLGLLETG
RIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEAIKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDT
GIEHDVALGRADAFVMDRLSALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALK
WFGTDISQ

Sequences:

>Translated_248_residues
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRNDYKVEFVTANFSGLLGLLETG
RIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEAIKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDT
GIEHDVALGRADAFVMDRLSALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALK
WFGTDISQ
>Mature_248_residues
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRNDYKVEFVTANFSGLLGLLETG
RIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEAIKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDT
GIEHDVALGRADAFVMDRLSALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALK
WFGTDISQ

Specific function: Probably part of a binding-protein-dependent transport system for an amino acid [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=227, Percent_Identity=41.4096916299559, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787031, Length=256, Percent_Identity=33.59375, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788649, Length=246, Percent_Identity=28.4552845528455, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788648, Length=238, Percent_Identity=28.9915966386555, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787085, Length=244, Percent_Identity=25.4098360655738, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787088, Length=239, Percent_Identity=25.5230125523013, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 27303; Mature: 27303

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRND
CCHHHHHHHHHHHHHHHHHEEHEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHCCCCC
YKVEFVTANFSGLLGLLETGRIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEA
EEEEEEEECHHHHHHHHHCCCEEECCCEEEEEECCCCEEEECCCEEECCCEEEEECCCHH
IKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDTGIEHDVALGRADAFVMDRLS
HHCHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHH
ALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALK
HHHHHHHCCCCEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
WFGTDISQ
HHCCCCCC
>Mature Secondary Structure
MKHWFNIALAALALSSATVQAATEVKVGMSGRYFPFTFVKQDELQGFEVDVWNEIGKRND
CCHHHHHHHHHHHHHHHHHEEHEEEEECCCCCCCEEEEEECCCCCCCEEEHHHHHCCCCC
YKVEFVTANFSGLLGLLETGRIDTISNQITITDARKAKYLFSDPYVIDGAQITVRKGNEA
EEEEEEEECHHHHHHHHHCCCEEECCCEEEEEECCCCEEEECCCEEECCCEEEEECCCHH
IKGIDDLAGKTVAVNLGSNFEQLLRNHDKDGKINIKTYDTGIEHDVALGRADAFVMDRLS
HHCHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHH
ALELIEKTGLPLQLAGSPFETIENAWPFVNNEKGQQLQGEVNKALAAMRADGTLSQIALK
HHHHHHHCCCCEEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
WFGTDISQ
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA