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The map label for this gene is alr [H]

Identifier: 226950848

GI number: 226950848

Start: 3904491

End: 3905651

Strand: Reverse

Name: alr [H]

Synonym: CLM_3860

Alternate gene names: 226950848

Gene position: 3905651-3904491 (Counterclockwise)

Preceding gene: 226950849

Following gene: 226950847

Centisome position: 93.99

GC content: 30.75

Gene sequence:

>1161_bases
TTGTTTAGAAATTTAAGAGCAGTATGGGCAGAAATCGATCTAGATAATTTACAACATAACTTAAAACAAATAAAAAAAAT
ATGTGGAAATAAAGAAATAATAGGGGTTATAAAGGCTAATGCATATGGACATGGAGCCATGGAAATAGCCCCTACTCTTT
TAGAAAATGGAGTAAGTAGATTAGCAGTGGCGGTTTTAAGTGAGGCTATGGAGCTTAGAATGAGTGGAGTAAAGGAGCCC
ATTATGATATTAGGTTATACACCATGGGCTTTAGGAGATATGCTTTTAGATAATGATATAGAACAATCTGTATACTCTTA
TAATGATGCTTTAGAATTATCTAAAATAGCGGTGCTAAAAAGAAAAATATTAAAAATACATATAGTGGTAGATACTGGCA
TGGGGAGAATTGGGTTTTTACCTACAAAAGAAAGTGTAGAAGATGTATATAAAATAAGTAAGTTGCCTAATATTGAAATA
GAAGGGGTATTTTCTCATTTTTCTTCTGCTGACGAGTCAGACAAAGATTATACTTTGTATCAAATGAATAAGTACAATGC
ATTTATAAACAAATTAGAGGAGAAAAATATTCAAGTACCTATAAAGCATATTGCTAATAGCGCAGCTATAATTGATTTAG
AAAATACTCATTTAGATGCAGTAAGAGCGGGTATTATAATGTATGGATACTATCCGTCCAATTATGTACTAAGAAATAAT
ATAAATCTGAAACCAGTAATGTCTTTAAAAACCAGTATAGTACACATAAAAAAAGTATCTTCGGGAGAATATATAAGTTA
TGGCGGAACTTTCAAAACAAAGAGAGAAAGCATAATAGCTACCTTACCTATAGGTTATGCAGATGGATATAATAGATTAT
TAAGCAATAAAGGAAAAGTTATAGTTAACGGCAAACTTGCTCCAGTAATAGGAAGAGTTTGTATGGATCAATGTATGATA
GATGTAACTTTTATAGAAAATTTAAAAGTTGGAGATGTGGTTACAATTATGGGGGAGGAAAATGGAGTAAGCTATACTGC
AGAGGATATAGCATCACAAATAGGCACTATAAGTTATGAAGTTATATGTAATGTAAATAAGAGGGTACCAAGAGTATATA
AGAAGGATGGCAAAATTATAAATGTAGTAAATTACATATAA

Upstream 100 bases:

>100_bases
AGTTATAAATTATACAAATTTTATACCAAATAGTAATTTGGATAAAAAATTATTTAATCCAGATAGCTTATAAAATTTAT
TTTAGAAAGCAGGGAAGATT

Downstream 100 bases:

>100_bases
AGTTTATATAAAAACATATTTATATATAATTTACATAATAATACATAATTGTATTAAAATAAACTTTGACATTGAAATTC
CTAAAACTCTATAATTAAAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MFRNLRAVWAEIDLDNLQHNLKQIKKICGNKEIIGVIKANAYGHGAMEIAPTLLENGVSRLAVAVLSEAMELRMSGVKEP
IMILGYTPWALGDMLLDNDIEQSVYSYNDALELSKIAVLKRKILKIHIVVDTGMGRIGFLPTKESVEDVYKISKLPNIEI
EGVFSHFSSADESDKDYTLYQMNKYNAFINKLEEKNIQVPIKHIANSAAIIDLENTHLDAVRAGIIMYGYYPSNYVLRNN
INLKPVMSLKTSIVHIKKVSSGEYISYGGTFKTKRESIIATLPIGYADGYNRLLSNKGKVIVNGKLAPVIGRVCMDQCMI
DVTFIENLKVGDVVTIMGEENGVSYTAEDIASQIGTISYEVICNVNKRVPRVYKKDGKIINVVNYI

Sequences:

>Translated_386_residues
MFRNLRAVWAEIDLDNLQHNLKQIKKICGNKEIIGVIKANAYGHGAMEIAPTLLENGVSRLAVAVLSEAMELRMSGVKEP
IMILGYTPWALGDMLLDNDIEQSVYSYNDALELSKIAVLKRKILKIHIVVDTGMGRIGFLPTKESVEDVYKISKLPNIEI
EGVFSHFSSADESDKDYTLYQMNKYNAFINKLEEKNIQVPIKHIANSAAIIDLENTHLDAVRAGIIMYGYYPSNYVLRNN
INLKPVMSLKTSIVHIKKVSSGEYISYGGTFKTKRESIIATLPIGYADGYNRLLSNKGKVIVNGKLAPVIGRVCMDQCMI
DVTFIENLKVGDVVTIMGEENGVSYTAEDIASQIGTISYEVICNVNKRVPRVYKKDGKIINVVNYI
>Mature_386_residues
MFRNLRAVWAEIDLDNLQHNLKQIKKICGNKEIIGVIKANAYGHGAMEIAPTLLENGVSRLAVAVLSEAMELRMSGVKEP
IMILGYTPWALGDMLLDNDIEQSVYSYNDALELSKIAVLKRKILKIHIVVDTGMGRIGFLPTKESVEDVYKISKLPNIEI
EGVFSHFSSADESDKDYTLYQMNKYNAFINKLEEKNIQVPIKHIANSAAIIDLENTHLDAVRAGIIMYGYYPSNYVLRNN
INLKPVMSLKTSIVHIKKVSSGEYISYGGTFKTKRESIIATLPIGYADGYNRLLSNKGKVIVNGKLAPVIGRVCMDQCMI
DVTFIENLKVGDVVTIMGEENGVSYTAEDIASQIGTISYEVICNVNKRVPRVYKKDGKIINVVNYI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=372, Percent_Identity=31.989247311828, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787439, Length=370, Percent_Identity=31.3513513513514, Blast_Score=165, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43063; Mature: 43063

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNLRAVWAEIDLDNLQHNLKQIKKICGNKEIIGVIKANAYGHGAMEIAPTLLENGVSR
CCCCHHHHHEECCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHH
LAVAVLSEAMELRMSGVKEPIMILGYTPWALGDMLLDNDIEQSVYSYNDALELSKIAVLK
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
RKILKIHIVVDTGMGRIGFLPTKESVEDVYKISKLPNIEIEGVFSHFSSADESDKDYTLY
HEEEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCCCCEEEE
QMNKYNAFINKLEEKNIQVPIKHIANSAAIIDLENTHLDAVRAGIIMYGYYPSNYVLRNN
EEHHHHHHHHHHHHCCCEEEHHHCCCCEEEEEECCCCHHHHHCCEEEEEEECCCEEEECC
INLKPVMSLKTSIVHIKKVSSGEYISYGGTFKTKRESIIATLPIGYADGYNRLLSNKGKV
CCCCCHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCE
IVNGKLAPVIGRVCMDQCMIDVTFIENLKVGDVVTIMGEENGVSYTAEDIASQIGTISYE
EECCCHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCEEEHHHHHHHHCCEEEE
VICNVNKRVPRVYKKDGKIINVVNYI
EEECCCHHCCHHHHCCCCEEEEEECC
>Mature Secondary Structure
MFRNLRAVWAEIDLDNLQHNLKQIKKICGNKEIIGVIKANAYGHGAMEIAPTLLENGVSR
CCCCHHHHHEECCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHH
LAVAVLSEAMELRMSGVKEPIMILGYTPWALGDMLLDNDIEQSVYSYNDALELSKIAVLK
HHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHH
RKILKIHIVVDTGMGRIGFLPTKESVEDVYKISKLPNIEIEGVFSHFSSADESDKDYTLY
HEEEEEEEEEECCCCCEECCCCHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCCCCCEEEE
QMNKYNAFINKLEEKNIQVPIKHIANSAAIIDLENTHLDAVRAGIIMYGYYPSNYVLRNN
EEHHHHHHHHHHHHCCCEEEHHHCCCCEEEEEECCCCHHHHHCCEEEEEEECCCEEEECC
INLKPVMSLKTSIVHIKKVSSGEYISYGGTFKTKRESIIATLPIGYADGYNRLLSNKGKV
CCCCCHHHHHHEEEEEEEECCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHCCCCCE
IVNGKLAPVIGRVCMDQCMIDVTFIENLKVGDVVTIMGEENGVSYTAEDIASQIGTISYE
EECCCHHHHHHHHHHHHHHEEEEEECCCCCCCEEEEEECCCCCEEEHHHHHHHHCCEEEE
VICNVNKRVPRVYKKDGKIINVVNYI
EEECCCHHCCHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]