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The map label for this gene is speD

Identifier: 226950800

GI number: 226950800

Start: 3854232

End: 3854582

Strand: Reverse

Name: speD

Synonym: CLM_3811

Alternate gene names: 226950800

Gene position: 3854582-3854232 (Counterclockwise)

Preceding gene: 226950801

Following gene: 226950798

Centisome position: 92.76

GC content: 29.63

Gene sequence:

>351_bases
TTGAAATATTCAGGGTATCACTTGGTAATCGATTTATTTGGTTGTAATTTTGACCAGCTAGAAAATACAGAATATATTAT
AGAAATGCTTAAAAAATTAGCAAGGGCACTGGATACCAAAATCGTTGCAAAAGCATTTCACAAGTTCCATCCACAAGGAT
TTAGTGGTGCATTAATCATTTCAGAATCACATATAACAATACATACATGGCCGGAAGATGCTTATATAGGAATTGATATA
TTTACATGTTCTAAATGTTTTGATCCTAGAAAAATAGTAGCTTATTTAAAAGAAAACTTAATATTTAAAAAGGTGGAAAT
CAAGGAAATACTGAGAGGTAAAATTGATTGA

Upstream 100 bases:

>100_bases
AAGATGATGCAATATTTGATATCAATTTTTACAAAATTTAAGATACAACTTTAAAACAACACAATTAACAATGGAATTAA
ATTTGGAAGGAGGTTTAATT

Downstream 100 bases:

>100_bases
TATTACCACCTTGGATTTAAAAATGACATAAATTATCTCTAAATAGGTGTACAGTGAAGAGTTCCTTTGAAACATTTAGA
GTATATTGTATAAATAATTA

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDI
FTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID

Sequences:

>Translated_116_residues
MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDI
FTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID
>Mature_116_residues
MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDI
FTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH_CLOB1 (A7FYV9)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385682.1
- ProteinModelPortal:   A7FYV9
- SMR:   A7FYV9
- STRING:   A7FYV9
- GeneID:   5397607
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3421
- eggNOG:   COG1586
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   CLSK972419
- BioCyc:   CBOT441770:CLB_3421-MONOMER
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 13438; Mature: 13438

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: ACT_SITE 63-63 ACT_SITE 68-68 ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALII
CCCCCEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
SESHITIHTWPEDAYIGIDIFTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID
ECCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALII
CCCCCEEEEEEEECCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
SESHITIHTWPEDAYIGIDIFTCSKCFDPRKIVAYLKENLIFKKVEIKEILRGKID
ECCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA