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The map label for this gene is fldA [H]

Identifier: 226950717

GI number: 226950717

Start: 3740668

End: 3741906

Strand: Reverse

Name: fldA [H]

Synonym: CLM_3725

Alternate gene names: 226950717

Gene position: 3741906-3740668 (Counterclockwise)

Preceding gene: 226950718

Following gene: 226950716

Centisome position: 90.05

GC content: 33.49

Gene sequence:

>1239_bases
ATGGAAAACAATGCAAATATGTTTAGTGGAGTAAAGGTTATTGAATTAGCAAATTTTATAGCTGCTCCAGCAGCAGGTAG
ATTTTTTGCTGATGGCGGTGCAGAGGTAATAAAAATTGAATCACCTGCTGGAGATCCTTTAAGATATACAGCTCCATCAG
AAGGAAGACCATTAAGCCAAGAAGAAAATACTACTTATGATTTGGAAAATGCAAATAAAAAGGCAATAGTTTTAAACCTC
AAAAGTGAAAAAGGTAAAAAGATATTACATGAAATGTTGAAAGAAGCAGATATATTATTAACTAACTGGAGAACAAAGGC
TTTAGTTAAACAAGGATTAGACTATGAAACACTAAAAGAAAAATATCCTAAGCTAGTTTTTGCACAAATAACTGGCTATG
GTGAAAAGGGCCCGGATAAGGATCTTCCAGGCTTCGATTATACTGCATTTTTCGCTAGAGGTGGTGTTTCAGGTACTCTT
TATGAAAAAGGAACTGTGCCTCCAAATGTTGTTCCAGGACTTGGAGACCATCAAGCTGGTATGTTTTTAGCAGCAGGTAT
GGCAGGAGCTTTATATAAAGCAAAAACAACAGGAAAAGGAGATAAGGTAACAGTAAGTTTAATGCATAGCGCTATGTATG
GATTAGGTATTATGATACAGGCTGCTCAATATACAGATCATGGTTTAGTATATCCAATAAATCGTAATGAAACTCCAAAC
CCATTTATAGTTTCATATAAATCTAAGGATGATTATTTTGTTCAAGTATGTATGCCACCATATGATGTTTTCTATGATAG
ATTTATGACTGCTTTAGGTAGAGAAGATTTAGTTGGAGATGAAAGATACAACAAGATAGAAAATTTAAAAGATGGACGTG
CGAAGGAAGTATATAAGATAATTGAAGAACAAATGGTTACAAAGACAAAGGATGAATGGGATAAAATATTTAGAGAAGCG
GATATTCCATTTGCTATTGCACAAACTTGGGAAGATTTACTACAAGATGAACAAGCTTGGGCAAATGATTATTTATACAA
GATGAAATATCCAACAGGAAATGAAAGGGCATTAGTAAGACTTCCAGTATTCTTTAAAGAAGCTGGATTACCAGAGTATA
AGCAATCACCACAGATAGCAGAAAATACTGCAGAAGTTTTAAAAGAAATGGGATACACAGAAGAAGATATTCAAGAATTA
GAAAAAAATAAAGATATTATGGTAAGGAAGGAAAAATAA

Upstream 100 bases:

>100_bases
TAAAAGAATGCTTTGAAAAAAAGTTTGAATTAAGACAATCTATTTAAATTAATAATAAATAAATTAAATTAATAATAAAT
CTATTTAAGGAGGCTTTTTT

Downstream 100 bases:

>100_bases
TGGCAGATATTTATACTATGGGTGTAGATATAGGTTCAACTGCATCAAAAACAGTAGTATTAAAAAATGGAAAAGAAATT
GTAAGTCAGGCAGTAATAAA

Product: E-cinnamoyl-CoA:R-phenyllactate CoA transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MENNANMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQEENTTYDLENANKKAIVLNL
KSEKGKKILHEMLKEADILLTNWRTKALVKQGLDYETLKEKYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTL
YEKGTVPPNVVPGLGDHQAGMFLAAGMAGALYKAKTTGKGDKVTVSLMHSAMYGLGIMIQAAQYTDHGLVYPINRNETPN
PFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYKIIEEQMVTKTKDEWDKIFREA
DIPFAIAQTWEDLLQDEQAWANDYLYKMKYPTGNERALVRLPVFFKEAGLPEYKQSPQIAENTAEVLKEMGYTEEDIQEL
EKNKDIMVRKEK

Sequences:

>Translated_412_residues
MENNANMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQEENTTYDLENANKKAIVLNL
KSEKGKKILHEMLKEADILLTNWRTKALVKQGLDYETLKEKYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTL
YEKGTVPPNVVPGLGDHQAGMFLAAGMAGALYKAKTTGKGDKVTVSLMHSAMYGLGIMIQAAQYTDHGLVYPINRNETPN
PFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYKIIEEQMVTKTKDEWDKIFREA
DIPFAIAQTWEDLLQDEQAWANDYLYKMKYPTGNERALVRLPVFFKEAGLPEYKQSPQIAENTAEVLKEMGYTEEDIQEL
EKNKDIMVRKEK
>Mature_412_residues
MENNANMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQEENTTYDLENANKKAIVLNL
KSEKGKKILHEMLKEADILLTNWRTKALVKQGLDYETLKEKYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTL
YEKGTVPPNVVPGLGDHQAGMFLAAGMAGALYKAKTTGKGDKVTVSLMHSAMYGLGIMIQAAQYTDHGLVYPINRNETPN
PFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYKIIEEQMVTKTKDEWDKIFREA
DIPFAIAQTWEDLLQDEQAWANDYLYKMKYPTGNERALVRLPVFFKEAGLPEYKQSPQIAENTAEVLKEMGYTEEDIQEL
EKNKDIMVRKEK

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=416, Percent_Identity=28.6057692307692, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI300863124, Length=442, Percent_Identity=26.9230769230769, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI300863126, Length=400, Percent_Identity=27.25, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI42794625, Length=408, Percent_Identity=25.9803921568627, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI266456254, Length=402, Percent_Identity=25.8706467661692, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI13376042, Length=442, Percent_Identity=24.6606334841629, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI266458393, Length=268, Percent_Identity=25.7462686567164, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI266458397, Length=250, Percent_Identity=25.6, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI266458395, Length=148, Percent_Identity=28.3783783783784, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI42822893, Length=148, Percent_Identity=28.3783783783784, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788717, Length=421, Percent_Identity=26.1282660332542, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87082093, Length=361, Percent_Identity=27.1468144044321, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786222, Length=405, Percent_Identity=25.4320987654321, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI115535051, Length=320, Percent_Identity=25.9375, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=324, Percent_Identity=26.2345679012346, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648431, Length=405, Percent_Identity=28.3950617283951, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585488, Length=318, Percent_Identity=25.4716981132075, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 46427; Mature: 46427

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNANMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCEEECCCCCCCCCCC
EENTTYDLENANKKAIVLNLKSEKGKKILHEMLKEADILLTNWRTKALVKQGLDYETLKE
CCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCEEEECCHHHHHHHCCCCHHHHHH
KYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTLYEKGTVPPNVVPGLGDHQAG
HCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
MFLAAGMAGALYKAKTTGKGDKVTVSLMHSAMYGLGIMIQAAQYTDHGLVYPINRNETPN
HHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCC
PFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYKI
CEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCHHHHHHHH
IEEQMVTKTKDEWDKIFREADIPFAIAQTWEDLLQDEQAWANDYLYKMKYPTGNERALVR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEE
LPVFFKEAGLPEYKQSPQIAENTAEVLKEMGYTEEDIQELEKNKDIMVRKEK
ECHHHHHCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MENNANMFSGVKVIELANFIAAPAAGRFFADGGAEVIKIESPAGDPLRYTAPSEGRPLSQ
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECCCCCCEEECCCCCCCCCCC
EENTTYDLENANKKAIVLNLKSEKGKKILHEMLKEADILLTNWRTKALVKQGLDYETLKE
CCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCEEEECCHHHHHHHCCCCHHHHHH
KYPKLVFAQITGYGEKGPDKDLPGFDYTAFFARGGVSGTLYEKGTVPPNVVPGLGDHQAG
HCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCC
MFLAAGMAGALYKAKTTGKGDKVTVSLMHSAMYGLGIMIQAAQYTDHGLVYPINRNETPN
HHHHHHHHHHHEEECCCCCCCEEEHHHHHHHHHCCCEEEEEEEECCCCEEEEECCCCCCC
PFIVSYKSKDDYFVQVCMPPYDVFYDRFMTALGREDLVGDERYNKIENLKDGRAKEVYKI
CEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCHHCCCCHHHHHHHHCCCCHHHHHHHH
IEEQMVTKTKDEWDKIFREADIPFAIAQTWEDLLQDEQAWANDYLYKMKYPTGNERALVR
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEEE
LPVFFKEAGLPEYKQSPQIAENTAEVLKEMGYTEEDIQELEKNKDIMVRKEK
ECHHHHHCCCCCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]