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The map label for this gene is pqqL [C]

Identifier: 226950604

GI number: 226950604

Start: 3624841

End: 3626070

Strand: Reverse

Name: pqqL [C]

Synonym: CLM_3587

Alternate gene names: 226950604

Gene position: 3626070-3624841 (Counterclockwise)

Preceding gene: 226950608

Following gene: 226950603

Centisome position: 87.26

GC content: 26.67

Gene sequence:

>1230_bases
ATGTATGATGCGAAAAAGACTATATTAAAAAATGGAATAACCTTAGTTACTATAAAGAAGGATACCCAAATAGCTGCTAT
TCATGCAGGGATAAAGATAGGATCTATATATGAAAGTGAAAAAGAAAAGGGTATAAGTCATTTTATAGAACATATGCTCT
TTAAAGGAACTAAATACAGAGATAATGAAACTTTAAATAGAGAATTAGAAAATTTAGGCGGGGAATATAATGCATATACA
GATAGTAATTCTACAGTATGTAGTATAACTGTTTTAGAAGAAGAATTGGAAAAGTCTATAGAAATTTTAGGTGATATGTT
TCAAAATTGTCTATTCCCTCAGGAAGAAATAGAAAGGGAAAGAGAGGTAATTTTATCTGAAATAAGAGGAAGTAAGGACG
ACTTAGAGGATTATTCTTTTAAAAAGGTAAATGAAACAGCTTTTGATAAAAGTCCATTAAAATATGATACTTTAGGAAAT
GAGAAAATAGTAAAATCTTTTACTAGAGACAAATTTATAAAATTTTATGAAAGATATTATGTACCTAATAATTGTTTTAT
ATCTATAGTTTCGGACTTCCCACATAATTACGTAGTAAGTATTGTGGAAAAGTATTTTAAAGATTGGTTATGGAAAGAAT
TTAAAAGAGAAAAAGTCTTAGAAGAAAAGAATAGATTTTTAAAAAAAGTTTCTTACAAAAATAATGTAGAACAAAGTACA
GTAGTATATTTATTTACATTACATGGCTTAAGTAAAAAAGAGGAGTTAGCACTTACAATATTAAGTCACAGGCTAGGTGA
AAGTGGAAATTCTGTATTGTTTAGAGAACTTAGGGAAAAGAGGGGATTTGCCTACGATGTATACACAGATTTGGATTTAT
CACCTTATGTAAAGACTTTGTATATATATACCTCAGTAGGAAGAGAAAATGTAGATGAAACTTTAGATGTTATAAATAAT
TGCATAGAAAGTATAAAGAAAGGTAGTATAGGTTTTGATAGTAATACTATAAATCTTATGAAAAAGATATTAAAAACAGC
TATTGCTTTTACTCTAGAGGACGTAACTGATATAGGAAATTATGCTTTTCATCAAATAATAGATGAGGAAAATATTTTTC
AGTTCTATGAAGATATGAAAGATTTAGATGGAATAAAAGAAGAAGATATATATAATGTAGCTAATAAAGTATTAAATAAA
CCTACTATACACATACTTTTAAATCAATAA

Upstream 100 bases:

>100_bases
AATATAGTCAATTAAATTGAAATACTTTACTTAAACTATGTACAGGTCTATATTTATAAACTATAATGGTGTAAATATGT
AATTTAAAAAGGTGATGTAA

Downstream 100 bases:

>100_bases
CCGTTTCGGGAGTGCAAAAATATGTCAAATATTATTACTAAAATAGAAGTTCAAAAGAGGAATAAAGATAGGGTAAATGT
TTATATAGATGAAGAGTTTA

Product: peptidase, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MYDAKKTILKNGITLVTIKKDTQIAAIHAGIKIGSIYESEKEKGISHFIEHMLFKGTKYRDNETLNRELENLGGEYNAYT
DSNSTVCSITVLEEELEKSIEILGDMFQNCLFPQEEIEREREVILSEIRGSKDDLEDYSFKKVNETAFDKSPLKYDTLGN
EKIVKSFTRDKFIKFYERYYVPNNCFISIVSDFPHNYVVSIVEKYFKDWLWKEFKREKVLEEKNRFLKKVSYKNNVEQST
VVYLFTLHGLSKKEELALTILSHRLGESGNSVLFRELREKRGFAYDVYTDLDLSPYVKTLYIYTSVGRENVDETLDVINN
CIESIKKGSIGFDSNTINLMKKILKTAIAFTLEDVTDIGNYAFHQIIDEENIFQFYEDMKDLDGIKEEDIYNVANKVLNK
PTIHILLNQ

Sequences:

>Translated_409_residues
MYDAKKTILKNGITLVTIKKDTQIAAIHAGIKIGSIYESEKEKGISHFIEHMLFKGTKYRDNETLNRELENLGGEYNAYT
DSNSTVCSITVLEEELEKSIEILGDMFQNCLFPQEEIEREREVILSEIRGSKDDLEDYSFKKVNETAFDKSPLKYDTLGN
EKIVKSFTRDKFIKFYERYYVPNNCFISIVSDFPHNYVVSIVEKYFKDWLWKEFKREKVLEEKNRFLKKVSYKNNVEQST
VVYLFTLHGLSKKEELALTILSHRLGESGNSVLFRELREKRGFAYDVYTDLDLSPYVKTLYIYTSVGRENVDETLDVINN
CIESIKKGSIGFDSNTINLMKKILKTAIAFTLEDVTDIGNYAFHQIIDEENIFQFYEDMKDLDGIKEEDIYNVANKVLNK
PTIHILLNQ
>Mature_409_residues
MYDAKKTILKNGITLVTIKKDTQIAAIHAGIKIGSIYESEKEKGISHFIEHMLFKGTKYRDNETLNRELENLGGEYNAYT
DSNSTVCSITVLEEELEKSIEILGDMFQNCLFPQEEIEREREVILSEIRGSKDDLEDYSFKKVNETAFDKSPLKYDTLGN
EKIVKSFTRDKFIKFYERYYVPNNCFISIVSDFPHNYVVSIVEKYFKDWLWKEFKREKVLEEKNRFLKKVSYKNNVEQST
VVYLFTLHGLSKKEELALTILSHRLGESGNSVLFRELREKRGFAYDVYTDLDLSPYVKTLYIYTSVGRENVDETLDVINN
CIESIKKGSIGFDSNTINLMKKILKTAIAFTLEDVTDIGNYAFHQIIDEENIFQFYEDMKDLDGIKEEDIYNVANKVLNK
PTIHILLNQ

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=205, Percent_Identity=29.2682926829268, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI94538354, Length=208, Percent_Identity=31.25, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1787770, Length=185, Percent_Identity=28.1081081081081, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17553678, Length=266, Percent_Identity=28.9473684210526, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71999683, Length=202, Percent_Identity=31.6831683168317, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6323192, Length=429, Percent_Identity=25.6410256410256, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321813, Length=205, Percent_Identity=20.4878048780488, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357875, Length=196, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646943, Length=196, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24641429, Length=321, Percent_Identity=25.5451713395639, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47652; Mature: 47652

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDAKKTILKNGITLVTIKKDTQIAAIHAGIKIGSIYESEKEKGISHFIEHMLFKGTKYR
CCCHHHHHHHCCCEEEEEECCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DNETLNRELENLGGEYNAYTDSNSTVCSITVLEEELEKSIEILGDMFQNCLFPQEEIERE
CCHHHHHHHHHCCCCCCCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
REVILSEIRGSKDDLEDYSFKKVNETAFDKSPLKYDTLGNEKIVKSFTRDKFIKFYERYY
HHHHHHHHCCCCCCHHHCCHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
VPNNCFISIVSDFPHNYVVSIVEKYFKDWLWKEFKREKVLEEKNRFLKKVSYKNNVEQST
CCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVYLFTLHGLSKKEELALTILSHRLGESGNSVLFRELREKRGFAYDVYTDLDLSPYVKTL
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
YIYTSVGRENVDETLDVINNCIESIKKGSIGFDSNTINLMKKILKTAIAFTLEDVTDIGN
HEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAFHQIIDEENIFQFYEDMKDLDGIKEEDIYNVANKVLNKPTIHILLNQ
HHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MYDAKKTILKNGITLVTIKKDTQIAAIHAGIKIGSIYESEKEKGISHFIEHMLFKGTKYR
CCCHHHHHHHCCCEEEEEECCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCC
DNETLNRELENLGGEYNAYTDSNSTVCSITVLEEELEKSIEILGDMFQNCLFPQEEIERE
CCHHHHHHHHHCCCCCCCEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
REVILSEIRGSKDDLEDYSFKKVNETAFDKSPLKYDTLGNEKIVKSFTRDKFIKFYERYY
HHHHHHHHCCCCCCHHHCCHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
VPNNCFISIVSDFPHNYVVSIVEKYFKDWLWKEFKREKVLEEKNRFLKKVSYKNNVEQST
CCCCCEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VVYLFTLHGLSKKEELALTILSHRLGESGNSVLFRELREKRGFAYDVYTDLDLSPYVKTL
EEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
YIYTSVGRENVDETLDVINNCIESIKKGSIGFDSNTINLMKKILKTAIAFTLEDVTDIGN
HEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAFHQIIDEENIFQFYEDMKDLDGIKEEDIYNVANKVLNKPTIHILLNQ
HHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA