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The map label for this gene is apeA [H]

Identifier: 226950014

GI number: 226950014

Start: 2967953

End: 2969488

Strand: Reverse

Name: apeA [H]

Synonym: CLM_2967

Alternate gene names: 226950014

Gene position: 2969488-2967953 (Counterclockwise)

Preceding gene: 226950015

Following gene: 226950013

Centisome position: 71.46

GC content: 29.43

Gene sequence:

>1536_bases
ATGGTTGTAGAAGAAAAAAAAGTATTTATAAGAAAAATAAACTATTATCAATTAATTTATGTTAAAATAATAATAGAATA
TTATGGAAGAGGGGTGAAAGACTTAGGTGATGTTTATCACTTAAGTAGTACTATGGAAAAAGATTTAACTAAAAAATATG
AGTTAGCTTGGGATAAGTATTCTAAAGAAGATTTAACAAATGTTTTTGATTTATCAGAAAGATACAAAGATTTTATGTCC
AAGTGCAAAACAGAAAGAGAATGTGTAAAAGAATTCATAGTTCTAGCAGAAAAATGCGGATATAAAAATTTAGAGGAAAT
TATAAAAAATAATAAAAAATTAAAGTCTGGTGATAAGGTTTATGCAAATAATATGGATAAAACTTTAGCTTTATTTATTA
TAGGTAAAGAATCTATGGAAAAAGGACTAAGAATATTAGGAGCTCACGTAGACTCACCAAGATTAGATTTAAAACAAAAT
CCTTTATATGAAGATACAGATTTAGCTCTATTTAAAACTCATTATTATGGTGGAATAAAAAAATATCAATGGGTTACTCT
ACCATTATCTATTCACGGTGTAATAGTTAAGAAAGATGGAACTAAGATTAATGTGGTAGTGGGAGAGGAAGAATCAGATC
CTGTATTTGGTGTATCTGATCTATTAATTCATTTATCAGCAGATCAAATGGATAAAAAGGCTTCTAAAGTAGTAGAAGGA
GAAAATCTAAATGTACTAATAGGAAGTATGCCTATAGAGGATAAAGAAGCTAAAGATAGAGTAAGAAGAAATATATTAAA
ATTATTAAATGAAAAATATAAAATAGATGAAGAAGATTTTGTTTCAGCAGAATTAGAGGTAGTTCCAGCAGGAAAGGCTA
GAGATTATGGTTTTGATAGAAGTATGGTAATGGCTTATGGTCAAGATGATAGAATTTGTTCTTATACTTCTTTTGAAGCT
ATGATGAAAATGGACAAGGTAGATAAAACTTGTGTTACATTACTTGTAGATAAAGAAGAAATAGGTAGCGTAGGGGCAAC
CGGTATGCAATCTAAGTTTTTTGAAAATACAGTAGCAGAAATAATAAACTTAACGTCAAATAATTATAGTGATCTAAAAT
TAAGAAGATGCCTTACAAATTCGAAGATGTTATCTTCTGATGTATCTGCAGCTTTTGATCCTAATTATCCATCTGTTATG
GAAAAGAAAAATTCAGCTTATTTTGGAAAAGGTATAGTATTTAATAAATATACTGGATCTAGAGGAAAAGGTGGATCAAA
TGATGCAAATCCAGAATATATAGCTGAGATAAGAGCTATGATGGAAAAGCATAATGTATCATGGCAAACAGCAGAATTAG
GAAAAGTAGATCAAGGTGGTGGAGGTACTATAGCTTACATACTAGCTCAATACTCTATGGAAGTTATAGATTGTGGAGTT
GCTCTTCATAATATGCATGCACCTTGGGAAATAGCTAGTAAGGCAGATATTTATGAAGCTATGAGAGGTTACCATGCCTT
TTTATTAGAAGCATAA

Upstream 100 bases:

>100_bases
ATAATCTTCCCCCTATGAAAAATCCATATGGATATTTATACGTTTTAGGATTTACCCTTATCATATCTCTGTTTTTAGTT
TATTTATTTATAAGAAAAAA

Downstream 100 bases:

>100_bases
AATATCCTTATATATCAATGCTTTAGAGGTATTTTGGACACTATGTAAGATATAAAAATGAAAGCATGATAATATACAAA
AATAACCATGTAGTTTCCCT

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MVVEEKKVFIRKINYYQLIYVKIIIEYYGRGVKDLGDVYHLSSTMEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMS
KCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQN
PLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEG
ENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAELEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEA
MMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVM
EKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGV
ALHNMHAPWEIASKADIYEAMRGYHAFLLEA

Sequences:

>Translated_511_residues
MVVEEKKVFIRKINYYQLIYVKIIIEYYGRGVKDLGDVYHLSSTMEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMS
KCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQN
PLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEG
ENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAELEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEA
MMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVM
EKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGV
ALHNMHAPWEIASKADIYEAMRGYHAFLLEA
>Mature_511_residues
MVVEEKKVFIRKINYYQLIYVKIIIEYYGRGVKDLGDVYHLSSTMEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMS
KCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQN
PLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEG
ENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAELEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEA
MMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVM
EKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGV
ALHNMHAPWEIASKADIYEAMRGYHAFLLEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17552916, Length=459, Percent_Identity=22.4400871459695, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322746, Length=471, Percent_Identity=24.416135881104, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321905, Length=427, Percent_Identity=23.8875878220141, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 57934; Mature: 57934

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEEKKVFIRKINYYQLIYVKIIIEYYGRGVKDLGDVYHLSSTMEKDLTKKYELAWDKY
CCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKV
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
YANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYEDTDLALFKTHYYGGIK
EECCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCC
KYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEG
EEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHEEECHHHHHHHHHHHCCC
ENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAELEVVPAGKARDYGFDR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCCC
SMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAE
CEEEEECCCCCEECHHHHHHHHHHHHHCHHHEEEEECHHHHCCCCCCCHHHHHHHHHHHH
IINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKNSAYFGKGIVFNKYTGS
HHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCCCCEECCCEEEECCCCC
RGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALHNMHAPWEIASKADIYEAMRGYHAFLLEA
HHHCCCCCHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MVVEEKKVFIRKINYYQLIYVKIIIEYYGRGVKDLGDVYHLSSTMEKDLTKKYELAWDKY
CCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKV
CHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
YANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYEDTDLALFKTHYYGGIK
EECCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCC
KYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEG
EEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHEEECHHHHHHHHHHHCCC
ENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAELEVVPAGKARDYGFDR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCCCCC
SMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAE
CEEEEECCCCCEECHHHHHHHHHHHHHCHHHEEEEECHHHHCCCCCCCHHHHHHHHHHHH
IINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKNSAYFGKGIVFNKYTGS
HHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCCCCEECCCEEEECCCCC
RGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALHNMHAPWEIASKADIYEAMRGYHAFLLEA
HHHCCCCCHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]