| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is ftsK [H]
Identifier: 226949760
GI number: 226949760
Start: 2710345
End: 2712621
Strand: Reverse
Name: ftsK [H]
Synonym: CLM_2700
Alternate gene names: 226949760
Gene position: 2712621-2710345 (Counterclockwise)
Preceding gene: 226949761
Following gene: 226949759
Centisome position: 65.28
GC content: 29.82
Gene sequence:
>2277_bases ATGGCAAAGAAAAGAACTAAATCTAATAAAACAGAAAAAAAGAATAATGATATAACAGGTATAATTCTAATAAGTATGGG AATTTTTGTACTTTTTAGTGTGTTTTCCCCTTCTGCCTCTGGAATAGTTGGGAGTTTCATAAAAAAAGTACTTATAGCTG TATTAGGTTTAGGATCTTTAGTATTTCCAATACTAATAATATTCACAGGATGTTGCTTTATAGGAAAGAAGAATAAAATA AATTTGAACTCTAAATTTTATGGAATAGTTCTTTTTTCTATAAATACACTTTTATTTTTACAAATGATACTTTTAAAAAG TTATGGCACAGAAGATATAATGCTTGGCATATCAAAATTTTATAGAGAAGATACAATGATTCATGGTGGTATAATTTCTT ATCTAATAGATGTTCCTTTATATAAACTGTTTGGAACTATAGGATGTTACATATTGTTTATATGTGTTTATATAATAAGT TTTATATTAATATTTCAAGTATCCTTAGGTACTATACTACAGACTTTGCAGGTAAAAAGAAGTATAAAAAATAAAAAAGT TAAAGAAAAATCTATAGAAGATAAAGAAGACATAGACGGTATAGAAAAAGAATTAGCTCCGGACTTAGAAAAAGATGAAG GTTTAACTAGGAATATTAAAGACAAAATCAAAATATTAGATTTTATGAAAAACTCAGAAATAAAGGAAGGTCCACTAAAT ATCGTGGATAATTCTGTTAGTGAAAATATAGAAAAATCTAAAGAAGATACCGGGGAAGAGGCTATAAAAGAAGAGCTTAG TAAAAATATAAATGAAGGGAGAAACAACGTAAAAATAGAATATAACTATCCAACCTTAGAACTTTTAAAACAAAATATTC AGTCAAAACTAAATAAACAAGATAAAAAAGAACTTATAAATAACGCAAATAAGTTAGAGGAAACTTTAAGTAGTTTTGGT GTAGAAGCTAAAGTTATGCAAGTAAGTAGAGGACCTTCAGTTACAAGGTTTGAACTTCAACCTAATGCGGGAGTTAAAGT AAGTAAAATAGTAAATTTAGCAGACGATATAGCGCTAAATTTAGCAGCTTCAGGAGTTAGAATAGAGGCTCCTATACCAG GAAAATCTGCAGTAGGTATAGAAGTGCCAAACAAATCCTTAACACCGGTATATTTAAGAGAAGTTATAGAAGGAGATGAA TTTCAGAAATTTGATGATGGACTAGCTTTTGCTTTGGGAAAGGATATAAGTGGTAGTTGTGTAGTATCAGATTTATCAAA AATGCCTCACCTATTAATAGCAGGAGCTACAGGTTCAGGAAAAAGTGTATGTATAAATACATTAATAATAAGTATTTTAT ATAAATATTCTCCAGAAAATGTAAAATTACTTATGGTGGATCCAAAGGTAGTAGAACTTAGCATATATAATGGTATACCT CATTTATTGATTCCAGTAGTTACAGATCCTAAAAAAGCGGCAGGAGCTCTTCATTGGGCAGTAAATGAAATGACAAAGAG ATATTCTTTATTTGCAGAAAATAGTGTAAGAAATATAGAGGGATATAATAATTTATATGACCAGGGTAAAATAGAAAATA AATTACCTTATGTGGTAATAATAATAGATGAGCTTGCAGATTTAATGATGGTTTGTCCAAATGATATAGAAGACTACATA AGTAGATTAGCTCAAATGGCTAGAGCAGCAGGTATGCATTTAGTTATAGCAACACAAAGACCTTCTGTAGATGTTATAAC AGGAATAATAAAGGCAAATATACCTTCTAGAATATCCTTTGCAGTATCTAGTTCTATAGATTCTAGAACCATATTAGATA TGTCAGGAGCAGAAAAACTTTTAGGAAAAGGAGATATGTTATTTTATCCAACAGGATCTCCAAAACCTACTAGAATACAA GGAGCTTTTATATCTGAAAGTGAAGTGGAAAAGGTAGTTTCATGTATAAAGGATGAGCAAGGAGAAGCAGAATATAGAGA AGAAATAATAGATCAAATAGATACAGCTGTAAATGTAGAAGCCGGGGATGAGGATGAGCTTCTAGAAGAGGCTATAAGAA TATGTATACAATTAGGAGAGGTATCCACATCACTAATTCAAAGAAAACTTAGAATAGGATATAATAGGGCAGCAAGAATA ATAGAACAGCTAGAAGCTAAGGGAATAATTTCCGGAAGAGATGGTAATAAACCAAGACAAGTAATAATTGATAAAAACAA TGAAACCTACGGAAAATATTTCCGAGGAAATATGTAA
Upstream 100 bases:
>100_bases AGGTATGCATTAATTAATATAAAAGGATATAAAAGTTCAATGTAGAATCTATAAATGTAGCTTAAATTAAACATTACTAG TTGGGAGGTGAATTAAAAGT
Downstream 100 bases:
>100_bases ATACTTTTAAAATTCAAGTTACTTAATACTTGTAAAATTTCTTAAGTAGATTTAAAATGTTTCTTGTGACATAAAAAATG TAGGAGGGGAACAGGTGGAA
Product: DNA translocase FtsK/SpoIIIE
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 758; Mature: 757
Protein sequence:
>758_residues MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKI NLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIIS FILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGRNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFG VEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDE FQKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYI SRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQ GAFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
Sequences:
>Translated_758_residues MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKI NLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIIS FILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGRNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFG VEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDE FQKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYI SRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQ GAFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM >Mature_757_residues AKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSLVFPILIIFTGCCFIGKKNKIN LNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKFYREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISF ILIFQVSLGTILQTLQVKRSIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLNI VDNSVSENIEKSKEDTGEEAIKEELSKNINEGRNNVKIEYNYPTLELLKQNIQSKLNKQDKKELINNANKLEETLSSFGV EAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALNLAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEF QKFDDGLAFALGKDISGSCVVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIPH LLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVIIIDELADLMMVCPNDIEDYIS RLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISFAVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQG AFISESEVEKVVSCIKDEQGEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARII EQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM
Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind
COG id: COG1674
COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 FtsK domain [H]
Homologues:
Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=48.1481481481481, Blast_Score=431, Evalue=1e-122,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR018541 - InterPro: IPR002543 [H]
Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]
EC number: NA
Molecular weight: Translated: 84010; Mature: 83879
Theoretical pI: Translated: 6.43; Mature: 6.43
Prosite motif: PS50901 FTSK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSL CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH VFPILIIFTGCCFIGKKNKINLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKF HHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH YREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISFILIFQVSLGTILQTLQVKR HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGRNNVKIEYNYPTLELLKQNIQSKLNKQ HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCHH DKKELINNANKLEETLSSFGVEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALN HHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH LAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEFQKFDDGLAFALGKDISGSC EECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCH VVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCC HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVI CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCEEEE IIDELADLMMVCPNDIEDYISRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISF EHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEH AVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQGAFISESEVEKVVSCIKDEQ HHHCCCCCCEEEECCCHHHHHCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCC GEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI CCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM HHHHHHCCEEECCCCCCCCEEEEECCCCCHHHHHCCCC >Mature Secondary Structure AKKRTKSNKTEKKNNDITGIILISMGIFVLFSVFSPSASGIVGSFIKKVLIAVLGLGSL CCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH VFPILIIFTGCCFIGKKNKINLNSKFYGIVLFSINTLLFLQMILLKSYGTEDIMLGISKF HHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH YREDTMIHGGIISYLIDVPLYKLFGTIGCYILFICVYIISFILIFQVSLGTILQTLQVKR HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIKNKKVKEKSIEDKEDIDGIEKELAPDLEKDEGLTRNIKDKIKILDFMKNSEIKEGPLN HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCH IVDNSVSENIEKSKEDTGEEAIKEELSKNINEGRNNVKIEYNYPTLELLKQNIQSKLNKQ HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCHH DKKELINNANKLEETLSSFGVEAKVMQVSRGPSVTRFELQPNAGVKVSKIVNLADDIALN HHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH LAASGVRIEAPIPGKSAVGIEVPNKSLTPVYLREVIEGDEFQKFDDGLAFALGKDISGSC EECCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCCCCH VVSDLSKMPHLLIAGATGSGKSVCINTLIISILYKYSPENVKLLMVDPKVVELSIYNGIP HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCC HLLIPVVTDPKKAAGALHWAVNEMTKRYSLFAENSVRNIEGYNNLYDQGKIENKLPYVVI CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCEEEE IIDELADLMMVCPNDIEDYISRLAQMARAAGMHLVIATQRPSVDVITGIIKANIPSRISF EHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEH AVSSSIDSRTILDMSGAEKLLGKGDMLFYPTGSPKPTRIQGAFISESEVEKVVSCIKDEQ HHHCCCCCCEEEECCCHHHHHCCCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHCCC GEAEYREEIIDQIDTAVNVEAGDEDELLEEAIRICIQLGEVSTSLIQRKLRIGYNRAARI CCHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH IEQLEAKGIISGRDGNKPRQVIIDKNNETYGKYFRGNM HHHHHHCCEEECCCCCCCCEEEEECCCCCHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11466286 [H]