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The map label for this gene is 226949659

Identifier: 226949659

GI number: 226949659

Start: 2628578

End: 2629414

Strand: Reverse

Name: 226949659

Synonym: CLM_2596

Alternate gene names: NA

Gene position: 2629414-2628578 (Counterclockwise)

Preceding gene: 226949660

Following gene: 226949658

Centisome position: 63.28

GC content: 33.57

Gene sequence:

>837_bases
ATGAAGCTGATTGCACTTATAGAAAACAAATCTAACTCTGATCTTATAGGAGAACATGGATTAGCTATACATATTGAATA
TAATGGTAAGCACTATCTTTTAGATACAGGAGCATCTGATTATTTTACTGATAATGCCCTTAAATTAGGAGTGGATTTGA
GTAGAGTGGATGCTGCAATTCTTTCACATAGTCACTATGATCACTCTGGTGGCTATAATGGTTTTTTTCATATAAATAAG
AGGGCTAATGTGTATGTTAGAAAGGAAGCTAAAGAATTATGCTATGGTAAAATAGGACCATTTAAGCGCTATATTGGTAT
TCCAAAAGATATTTTAAATAAGTATGCAGATAGATTTATTTATGTACATGAAGATTATAAAATTAATGAAGGGGTATGGC
TTATTTCACACAATACTGATAACCTAGAGGCTAGAGGTAAAAAAGCTCATATGTATCGTATGACAAACAATGGACTAAAG
CCTGATGATTTTCATCATGAGCAAAGCTTAGTATTTGATACTGATGATGGTTTGGTAATCCTAAATAGTTGTTCGCATGG
TGGTATAGATAATATTGTGGAAGAAGTAAAGGCTACTTTTGAAGGTAAGAAAGTCTTAGCAGTTATCGGGGGATTTCATT
TAATGGGACTTACGGGTACAAGTTCTATGAGCATTAAATCTGAAGAAGTTGAAGCCCTTGGCAATCGTTTGGTTGATTTG
GGAGTAGAGCATATTTATACTTGTCATTGTACTGGAGACCCAGCTTATAAGATACTGAAGAAAACATTAGGTGATAGAGT
AGAATATTTTAGTACTGGAACTGTTGTAGAACTGTAA

Upstream 100 bases:

>100_bases
TAGTAAATGGTGTCTAGCAAATATGCTACAATAAAGTATAATGAAATTGTAAAATTAGACAAAGTAAGATTCGTTTATAT
TTTACAAAGGAGGACTATTT

Downstream 100 bases:

>100_bases
ATAGATTATAAATAAGATTTATTTATGTTGGATAAAGTCTATATAATAAAATATAACAAAATTAAATGAAGAGGTGAACA
ATTTGATTAAACATATTGTA

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLIALIENKSNSDLIGEHGLAIHIEYNGKHYLLDTGASDYFTDNALKLGVDLSRVDAAILSHSHYDHSGGYNGFFHINK
RANVYVRKEAKELCYGKIGPFKRYIGIPKDILNKYADRFIYVHEDYKINEGVWLISHNTDNLEARGKKAHMYRMTNNGLK
PDDFHHEQSLVFDTDDGLVILNSCSHGGIDNIVEEVKATFEGKKVLAVIGGFHLMGLTGTSSMSIKSEEVEALGNRLVDL
GVEHIYTCHCTGDPAYKILKKTLGDRVEYFSTGTVVEL

Sequences:

>Translated_278_residues
MKLIALIENKSNSDLIGEHGLAIHIEYNGKHYLLDTGASDYFTDNALKLGVDLSRVDAAILSHSHYDHSGGYNGFFHINK
RANVYVRKEAKELCYGKIGPFKRYIGIPKDILNKYADRFIYVHEDYKINEGVWLISHNTDNLEARGKKAHMYRMTNNGLK
PDDFHHEQSLVFDTDDGLVILNSCSHGGIDNIVEEVKATFEGKKVLAVIGGFHLMGLTGTSSMSIKSEEVEALGNRLVDL
GVEHIYTCHCTGDPAYKILKKTLGDRVEYFSTGTVVEL
>Mature_278_residues
MKLIALIENKSNSDLIGEHGLAIHIEYNGKHYLLDTGASDYFTDNALKLGVDLSRVDAAILSHSHYDHSGGYNGFFHINK
RANVYVRKEAKELCYGKIGPFKRYIGIPKDILNKYADRFIYVHEDYKINEGVWLISHNTDNLEARGKKAHMYRMTNNGLK
PDDFHHEQSLVFDTDDGLVILNSCSHGGIDNIVEEVKATFEGKKVLAVIGGFHLMGLTGTSSMSIKSEEVEALGNRLVDL
GVEHIYTCHCTGDPAYKILKKTLGDRVEYFSTGTVVEL

Specific function: Catalyzes the condensation of 6-hydroxymethyl-7,8- dihydropterin pyrophosphate (DHPP) with 4-(beta-D-ribofuranosyl)- aminobenzene-5'-phosphate (beta-RFA-P) to form 7,8-dihydropterin- 6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate, a precursor

COG id: COG1237

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31111; Mature: 31111

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIALIENKSNSDLIGEHGLAIHIEYNGKHYLLDTGASDYFTDNALKLGVDLSRVDAAI
CEEEEEEECCCCCCEECCCCEEEEEEECCEEEEEECCCCCCCCCCEEEECCCHHHHHHHH
LSHSHYDHSGGYNGFFHINKRANVYVRKEAKELCYGKIGPFKRYIGIPKDILNKYADRFI
HHCCCCCCCCCCCCEEEECCCCCEEEEECHHHHHHCCCCCHHHHCCCCHHHHHHHHHEEE
YVHEDYKINEGVWLISHNTDNLEARGKKAHMYRMTNNGLKPDDFHHEQSLVFDTDDGLVI
EEECCEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
LNSCSHGGIDNIVEEVKATFEGKKVLAVIGGFHLMGLTGTSSMSIKSEEVEALGNRLVDL
EECCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCCCEECHHHHHHHHHHHHHC
GVEHIYTCHCTGDPAYKILKKTLGDRVEYFSTGTVVEL
CCCEEEEEEECCCHHHHHHHHHHCCCEEEECCCCEEEC
>Mature Secondary Structure
MKLIALIENKSNSDLIGEHGLAIHIEYNGKHYLLDTGASDYFTDNALKLGVDLSRVDAAI
CEEEEEEECCCCCCEECCCCEEEEEEECCEEEEEECCCCCCCCCCEEEECCCHHHHHHHH
LSHSHYDHSGGYNGFFHINKRANVYVRKEAKELCYGKIGPFKRYIGIPKDILNKYADRFI
HHCCCCCCCCCCCCEEEECCCCCEEEEECHHHHHHCCCCCHHHHCCCCHHHHHHHHHEEE
YVHEDYKINEGVWLISHNTDNLEARGKKAHMYRMTNNGLKPDDFHHEQSLVFDTDDGLVI
EEECCEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEE
LNSCSHGGIDNIVEEVKATFEGKKVLAVIGGFHLMGLTGTSSMSIKSEEVEALGNRLVDL
EECCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCCCEECHHHHHHHHHHHHHC
GVEHIYTCHCTGDPAYKILKKTLGDRVEYFSTGTVVEL
CCCEEEEEEECCCHHHHHHHHHHCCCEEEECCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]