Click here to switch to the map view.

The map label for this gene is steT [H]

Identifier: 226948655

GI number: 226948655

Start: 1610362

End: 1611681

Strand: Direct

Name: steT [H]

Synonym: CLM_1550

Alternate gene names: 226948655

Gene position: 1610362-1611681 (Clockwise)

Preceding gene: 226948654

Following gene: 226948656

Centisome position: 38.75

GC content: 30.53

Gene sequence:

>1320_bases
ATGAAAAATGCTAAAGAAGAAAATTTCCAAAAAAACCTAGGATTATTTGATGCTATAGCTATAGTTATAGGTATGGTTAT
AGGATCAGGTATATTTTTTAAGCCAGCTATAGTTTTTAAAAATGCTGGTTCACCAATGTTAGGTATATTGGCTTGGTTAG
TTGGAGGCTTAATTACTATAGCTTCTGGCCTTACAGTAGCAGAAATTGCTGCAGCTATTCCTAAGACTGGGGGAATATTT
GTTTATATTAAAGAATTATATGGAGAAAAATTTGCATTTTTACTGGGATGGGTCCAATCAATTGTATATATACCAGGGTC
AGCGGCAGCTTTATCCATAATACTTTCTATACAGATTACTAGTTTTATACCTTTAACAGCTATTGAACAAAAAGTTTTAG
CTATAGTATTTATAATATTCATCATGATTTTAAATATTATATCTACTAAATTAGTAAGTAAAATGCAAGGGATAATAAGT
ATTGCTAAACTAATACCTATCATCGCTATAATAGCTTTAGGATTTATAAAGGGAACAGCAAAATGGGATATACTAAATAT
TAGTTCTTCAAGTACTGTATCTGGGTTTGGAGCTGCACTTTTAGGAACTTTATGGGCTTATGATGGATGGATAAGTGTAG
GTAATATGGCAGGAGAACTTAAAAATCCTAAAAAAGATTTGCCAAGATCTATAATAATAGGTTTAGGTACTACTATAGTA
GTGTATGTACTTATAAATTTAGCTCTAATTAATATAATGCCAATGGGTGCAATAATAACATCTGAAAAACCAGCTTCAGA
TGCAGCAGTAGTATTATTAGGAAGTACAGGAGCAAAAATCATTTCAGCAGGAATATTAATTTCTATATTCGGAGCCTTAA
ATGGATATTTAATGACAGGAGTTAGAATACCTTTAGCCATGTCTCAGGATAGGAGCATACCTTTTAGTAAGTATTTTAGT
AAAGTTCATGAAAAATCAGGAACACCAGTTAATGCCTTTATATTTGAAACTGTATTAGCTTGTCTATATGTATTATCAGG
ATCATTCAATGTACTAACGGACTTAGTGATGTTTATATTATGGCTATTCTTTATTATGGCGGTAGCAGGCATATTTGTTT
TAAGAACTAAATTTAAACATTTGGATAGACCCTATAAAGTGCCCTTATATCCATTAGTACCTCTTATAGGTATAATAGGA
ATTGGCTATATAATAATAAGTACATTAATAACAAATACTTTCTATGCTCTTTGTGGTATAGGAATAACCTTATTAGGTTT
ACCCGTTTATAGCTATATAAAAAAGAAGAATAAAGTATAA

Upstream 100 bases:

>100_bases
TTATATTTTTAATTTAAGATTATAGACTATAGTAGTTTATGGATAAAATTTTTTAGCAAAGTAATTTGATACTACATACT
AAAGAAAGGGAAGAAATGAT

Downstream 100 bases:

>100_bases
GCATTAGCTCACCATTATATATATTTTGATTTAATATATAAAGAAAAGCAGATTATAAAAAGTTATGGAACTTAGAATTT
TAAAGGATTCTAGAATTTTA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKNAKEENFQKNLGLFDAIAIVIGMVIGSGIFFKPAIVFKNAGSPMLGILAWLVGGLITIASGLTVAEIAAAIPKTGGIF
VYIKELYGEKFAFLLGWVQSIVYIPGSAAALSIILSIQITSFIPLTAIEQKVLAIVFIIFIMILNIISTKLVSKMQGIIS
IAKLIPIIAIIALGFIKGTAKWDILNISSSSTVSGFGAALLGTLWAYDGWISVGNMAGELKNPKKDLPRSIIIGLGTTIV
VYVLINLALINIMPMGAIITSEKPASDAAVVLLGSTGAKIISAGILISIFGALNGYLMTGVRIPLAMSQDRSIPFSKYFS
KVHEKSGTPVNAFIFETVLACLYVLSGSFNVLTDLVMFILWLFFIMAVAGIFVLRTKFKHLDRPYKVPLYPLVPLIGIIG
IGYIIISTLITNTFYALCGIGITLLGLPVYSYIKKKNKV

Sequences:

>Translated_439_residues
MKNAKEENFQKNLGLFDAIAIVIGMVIGSGIFFKPAIVFKNAGSPMLGILAWLVGGLITIASGLTVAEIAAAIPKTGGIF
VYIKELYGEKFAFLLGWVQSIVYIPGSAAALSIILSIQITSFIPLTAIEQKVLAIVFIIFIMILNIISTKLVSKMQGIIS
IAKLIPIIAIIALGFIKGTAKWDILNISSSSTVSGFGAALLGTLWAYDGWISVGNMAGELKNPKKDLPRSIIIGLGTTIV
VYVLINLALINIMPMGAIITSEKPASDAAVVLLGSTGAKIISAGILISIFGALNGYLMTGVRIPLAMSQDRSIPFSKYFS
KVHEKSGTPVNAFIFETVLACLYVLSGSFNVLTDLVMFILWLFFIMAVAGIFVLRTKFKHLDRPYKVPLYPLVPLIGIIG
IGYIIISTLITNTFYALCGIGITLLGLPVYSYIKKKNKV
>Mature_439_residues
MKNAKEENFQKNLGLFDAIAIVIGMVIGSGIFFKPAIVFKNAGSPMLGILAWLVGGLITIASGLTVAEIAAAIPKTGGIF
VYIKELYGEKFAFLLGWVQSIVYIPGSAAALSIILSIQITSFIPLTAIEQKVLAIVFIIFIMILNIISTKLVSKMQGIIS
IAKLIPIIAIIALGFIKGTAKWDILNISSSSTVSGFGAALLGTLWAYDGWISVGNMAGELKNPKKDLPRSIIIGLGTTIV
VYVLINLALINIMPMGAIITSEKPASDAAVVLLGSTGAKIISAGILISIFGALNGYLMTGVRIPLAMSQDRSIPFSKYFS
KVHEKSGTPVNAFIFETVLACLYVLSGSFNVLTDLVMFILWLFFIMAVAGIFVLRTKFKHLDRPYKVPLYPLVPLIGIIG
IGYIIISTLITNTFYALCGIGITLLGLPVYSYIKKKNKV

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI71979932, Length=443, Percent_Identity=31.3769751693002, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI33286428, Length=448, Percent_Identity=30.8035714285714, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI187423910, Length=403, Percent_Identity=31.7617866004963, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI7657591, Length=403, Percent_Identity=31.7617866004963, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI115648063, Length=448, Percent_Identity=27.2321428571429, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI115648022, Length=448, Percent_Identity=27.2321428571429, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI186910308, Length=436, Percent_Identity=27.5229357798165, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI186910306, Length=436, Percent_Identity=27.5229357798165, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI186910304, Length=436, Percent_Identity=27.5229357798165, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI7657683, Length=406, Percent_Identity=29.064039408867, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI9790235, Length=435, Percent_Identity=27.816091954023, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI33286430, Length=246, Percent_Identity=32.1138211382114, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI258614003, Length=431, Percent_Identity=22.969837587007, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4507047, Length=426, Percent_Identity=23.4741784037559, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI258614005, Length=431, Percent_Identity=22.969837587007, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI258645169, Length=431, Percent_Identity=22.969837587007, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI71999149, Length=425, Percent_Identity=24.7058823529412, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI110347453, Length=351, Percent_Identity=24.5014245014245, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87082250, Length=449, Percent_Identity=29.8440979955457, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI2367353, Length=350, Percent_Identity=27.4285714285714, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081708, Length=433, Percent_Identity=25.1732101616628, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788480, Length=437, Percent_Identity=24.2562929061785, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1786694, Length=454, Percent_Identity=23.7885462555066, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081915, Length=338, Percent_Identity=23.9644970414201, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790653, Length=436, Percent_Identity=20.1834862385321, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790575, Length=339, Percent_Identity=22.7138643067847, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=456, Percent_Identity=30.9210526315789, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71993915, Length=453, Percent_Identity=26.4900662251656, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17568033, Length=441, Percent_Identity=27.437641723356, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982612, Length=444, Percent_Identity=26.3513513513513, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71982608, Length=444, Percent_Identity=26.3513513513513, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71995382, Length=467, Percent_Identity=26.5524625267666, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71995388, Length=467, Percent_Identity=26.5524625267666, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32566699, Length=408, Percent_Identity=27.9411764705882, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32566695, Length=399, Percent_Identity=26.0651629072682, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193208714, Length=399, Percent_Identity=26.0651629072682, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71990446, Length=462, Percent_Identity=25.1082251082251, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982623, Length=273, Percent_Identity=26.7399267399267, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71987339, Length=368, Percent_Identity=25, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531343, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17532491, Length=349, Percent_Identity=22.3495702005731, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321492, Length=352, Percent_Identity=23.8636363636364, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321751, Length=399, Percent_Identity=25.31328320802, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641993, Length=403, Percent_Identity=29.2803970223325, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24641995, Length=403, Percent_Identity=29.2803970223325, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45550968, Length=438, Percent_Identity=28.5388127853881, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI19921172, Length=438, Percent_Identity=28.5388127853881, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21357367, Length=434, Percent_Identity=27.8801843317972, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24651635, Length=443, Percent_Identity=28.8939051918736, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24651633, Length=443, Percent_Identity=28.8939051918736, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI221331183, Length=432, Percent_Identity=28.2407407407407, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17647653, Length=432, Percent_Identity=28.2407407407407, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24664379, Length=432, Percent_Identity=28.2407407407407, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221512776, Length=416, Percent_Identity=23.3173076923077, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666159, Length=416, Percent_Identity=23.3173076923077, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667468, Length=416, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24668806, Length=409, Percent_Identity=23.2273838630807, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356285, Length=409, Percent_Identity=23.2273838630807, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668802, Length=409, Percent_Identity=23.2273838630807, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47094; Mature: 47094

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAKEENFQKNLGLFDAIAIVIGMVIGSGIFFKPAIVFKNAGSPMLGILAWLVGGLITI
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHH
ASGLTVAEIAAAIPKTGGIFVYIKELYGEKFAFLLGWVQSIVYIPGSAAALSIILSIQIT
HCCCHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SFIPLTAIEQKVLAIVFIIFIMILNIISTKLVSKMQGIISIAKLIPIIAIIALGFIKGTA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KWDILNISSSSTVSGFGAALLGTLWAYDGWISVGNMAGELKNPKKDLPRSIIIGLGTTIV
CEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHCCHHHHCCCCHHHCCHHHHHHHHHHHH
VYVLINLALINIMPMGAIITSEKPASDAAVVLLGSTGAKIISAGILISIFGALNGYLMTG
HHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
VRIPLAMSQDRSIPFSKYFSKVHEKSGTPVNAFIFETVLACLYVLSGSFNVLTDLVMFIL
EEECEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WLFFIMAVAGIFVLRTKFKHLDRPYKVPLYPLVPLIGIIGIGYIIISTLITNTFYALCGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITLLGLPVYSYIKKKNKV
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNAKEENFQKNLGLFDAIAIVIGMVIGSGIFFKPAIVFKNAGSPMLGILAWLVGGLITI
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHH
ASGLTVAEIAAAIPKTGGIFVYIKELYGEKFAFLLGWVQSIVYIPGSAAALSIILSIQIT
HCCCHHHHHHHHCCCCCCCEEEHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SFIPLTAIEQKVLAIVFIIFIMILNIISTKLVSKMQGIISIAKLIPIIAIIALGFIKGTA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KWDILNISSSSTVSGFGAALLGTLWAYDGWISVGNMAGELKNPKKDLPRSIIIGLGTTIV
CEEEEECCCCCCCHHHHHHHHHHHHHHCCHHHHCCHHHHCCCCHHHCCHHHHHHHHHHHH
VYVLINLALINIMPMGAIITSEKPASDAAVVLLGSTGAKIISAGILISIFGALNGYLMTG
HHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
VRIPLAMSQDRSIPFSKYFSKVHEKSGTPVNAFIFETVLACLYVLSGSFNVLTDLVMFIL
EEECEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WLFFIMAVAGIFVLRTKFKHLDRPYKVPLYPLVPLIGIIGIGYIIISTLITNTFYALCGI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITLLGLPVYSYIKKKNKV
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]