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The map label for this gene is noxA [H]

Identifier: 226948613

GI number: 226948613

Start: 1564974

End: 1566200

Strand: Direct

Name: noxA [H]

Synonym: CLM_1508

Alternate gene names: 226948613

Gene position: 1564974-1566200 (Clockwise)

Preceding gene: 226948612

Following gene: 226948615

Centisome position: 37.66

GC content: 29.18

Gene sequence:

>1227_bases
ATGAAATATGTGATAATAGGGGCTAGTGCAGCAGGAATTTCAGCAGTTAAAACTTTGAGAACATTAGATAAAGATTCTCA
AATAGTTATGATTTCTAAAGATGATAAAGTATATTCAAGATGTTTGCTGCATCATTTTATAGGTGGAAATAGAGAAATAG
AGGGATTATCTTTTATAGAAAAGGATTTTTTCGCTAAGTATAATGTGAAATGGATAAAAAATAAAAAAGTAGAAACTGTA
GATATAGATAAAAAGATAGTAAAAGTGCAAGGAAAAATTTCAGAACATTATGATAAATTACTTATAGCATCAGGTTCTTA
TGCGTCTATACCGCCGATTAAAAATTTAAGAGAAGCTAAAAGAGTGTACACTTTAAGGGATTTAGATGATGCAATAGCTA
TAAAAGAAGAGGCTAAAAAGATTAAAAAAGCAGCAGTAATAGGGGCAGGACTTGTTGGGATAGATGCTACTATGGGATTA
TTAGAAAACGACGTAGAGGTAACTGTTATAGAAATGGGAAATAGAATGCTTCCACTACAATTAGACCAAAGAGCATCAAA
AACTTACGAAGAATTATTTAGAAAACACAATGTTAATATAAAAACCAGTGTAGGAGCTGAAGAAGCTTTAATAGATGAGA
ATGAAAATGTTTGTGGGATAAAATTAAGTAATGGTGAAAAGATAGATTGTGATATTATAGTTGTAGCAGCAGGAGTTAGA
CCTAATATAGATTTTATAAAGGATGAAAGAATAAAGATAGAAAGAGGCATAGTTATAAATGATAATTGTGAAACTACAGT
TAAAGATATATATGCTGCAGGAGACGTAACCTTTAGAGCACCTATATGGCCAATAGCTATGAAACAAGGAAGGATAGCTG
CTTGTAATATGGCAGGAGAAAAGAAGCTATTAGATGATAATTTTGGTGCAAGAAATTCCATGAATTTTTTAGGGGTATAT
ACTATATCTTTAGGTATAGTAGAGCCAAAGGATGAAAGTTATAAAGTAGATATAATAGATAAAAATGGAGTTTATAAAAA
AATAATACACAAAGATGGAATCATATATGGAGCTATACTTCAGGGGGATATAGCTTATGCTGGAGTATTAACAGAACTAA
TAAAAAATAAAATAGATATATCAAAAATAAATAAGGACATATTTGATATAAGTTTTGCAGATTTTTTTAATATAAAAGAA
AATGGAGAATTTAGTTATAAAAAATAA

Upstream 100 bases:

>100_bases
GGATGTAAATAAATTAGCAGAGATTAGTATAAAATTTTCTCTAATAAGAATTTGATTTTATAATATTATAAAAAATATTA
AGGCTCAGGAGGTAAATAAT

Downstream 100 bases:

>100_bases
GGAAAGTGCGAGGCACTTTCCTTAAAATATTTTATTTAATCTCAGTTTTCATAAGTGGTTTTAGAGGTGACTTCTAACTT
TTTATCGGGTCTCTTAAATA

Product: nitrate reductase, NADH oxidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGKISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAAVIGAGLVGIDATMGL
LENDVEVTVIEMGNRMLPLQLDQRASKTYEELFRKHNVNIKTSVGAEEALIDENENVCGIKLSNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAACNMAGEKKLLDDNFGARNSMNFLGVY
TISLGIVEPKDESYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYKK

Sequences:

>Translated_408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGKISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAAVIGAGLVGIDATMGL
LENDVEVTVIEMGNRMLPLQLDQRASKTYEELFRKHNVNIKTSVGAEEALIDENENVCGIKLSNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAACNMAGEKKLLDDNFGARNSMNFLGVY
TISLGIVEPKDESYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYKK
>Mature_408_residues
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIEKDFFAKYNVKWIKNKKVETV
DIDKKIVKVQGKISEHYDKLLIASGSYASIPPIKNLREAKRVYTLRDLDDAIAIKEEAKKIKKAAVIGAGLVGIDATMGL
LENDVEVTVIEMGNRMLPLQLDQRASKTYEELFRKHNVNIKTSVGAEEALIDENENVCGIKLSNGEKIDCDIIVVAAGVR
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAACNMAGEKKLLDDNFGARNSMNFLGVY
TISLGIVEPKDESYKVDIIDKNGVYKKIIHKDGIIYGAILQGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKE
NGEFSYKK

Specific function: Required for nitrite assimilation [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=312, Percent_Identity=28.525641025641, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI65787454, Length=312, Percent_Identity=28.525641025641, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226437568, Length=312, Percent_Identity=28.525641025641, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1789765, Length=404, Percent_Identity=26.980198019802, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789065, Length=294, Percent_Identity=24.1496598639456, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788892, Length=219, Percent_Identity=24.2009132420091, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559934, Length=292, Percent_Identity=25.6849315068493, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639257, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI281359715, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281359713, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639250, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18543267, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639252, Length=352, Percent_Identity=25, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24585130, Length=312, Percent_Identity=23.7179487179487, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24581020, Length=355, Percent_Identity=24.2253521126761, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573993, Length=355, Percent_Identity=24.2253521126761, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585384, Length=228, Percent_Identity=26.7543859649123, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR013027
- InterPro:   IPR005117
- InterPro:   IPR012744
- InterPro:   IPR017121
- InterPro:   IPR006067
- InterPro:   IPR006066
- InterPro:   IPR001327 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01077 NIR_SIR; PF03460 NIR_SIR_ferr; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.7.1.4 [H]

Molecular weight: Translated: 45536; Mature: 45536

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIE
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHH
KDFFAKYNVKWIKNKKVETVDIDKKIVKVQGKISEHYDKLLIASGSYASIPPIKNLREAK
HHHHHCCCEEEECCCCEEEEECCCEEEEEECCHHHCCCEEEEECCCCCCCCCHHHHHHHH
RVYTLRDLDDAIAIKEEAKKIKKAAVIGAGLVGIDATMGLLENDVEVTVIEMGNRMLPLQ
HHEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEEEECCCEEECEE
LDQRASKTYEELFRKHNVNIKTSVGAEEALIDENENVCGIKLSNGEKIDCDIIVVAAGVR
CCHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCEEEEEECCCCEEEEEEEEEEECCC
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAACNMAGE
CCCCEECCCCEEEECCEEECCCCCHHHHHHHCCCCEEEECCCCEEEECCCCEEEECCCCC
KKLLDDNFGARNSMNFLGVYTISLGIVEPKDESYKVDIIDKNGVYKKIIHKDGIIYGAIL
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHCCCEEEEEEE
QGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKENGEFSYKK
ECCHHHHHHHHHHHHCCCCHHHHCCHHHEEEHHHEECCCCCCCCCCCC
>Mature Secondary Structure
MKYVIIGASAAGISAVKTLRTLDKDSQIVMISKDDKVYSRCLLHHFIGGNREIEGLSFIE
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHH
KDFFAKYNVKWIKNKKVETVDIDKKIVKVQGKISEHYDKLLIASGSYASIPPIKNLREAK
HHHHHCCCEEEECCCCEEEEECCCEEEEEECCHHHCCCEEEEECCCCCCCCCHHHHHHHH
RVYTLRDLDDAIAIKEEAKKIKKAAVIGAGLVGIDATMGLLENDVEVTVIEMGNRMLPLQ
HHEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCEEEEEECCCEEECEE
LDQRASKTYEELFRKHNVNIKTSVGAEEALIDENENVCGIKLSNGEKIDCDIIVVAAGVR
CCHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCEEEEEECCCCEEEEEEEEEEECCC
PNIDFIKDERIKIERGIVINDNCETTVKDIYAAGDVTFRAPIWPIAMKQGRIAACNMAGE
CCCCEECCCCEEEECCEEECCCCCHHHHHHHCCCCEEEECCCCEEEECCCCEEEECCCCC
KKLLDDNFGARNSMNFLGVYTISLGIVEPKDESYKVDIIDKNGVYKKIIHKDGIIYGAIL
CCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEECCCCHHHHHHCCCEEEEEEE
QGDIAYAGVLTELIKNKIDISKINKDIFDISFADFFNIKENGEFSYKK
ECCHHHHHHHHHHHHCCCCHHHHCCHHHEEEHHHEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7868621; 8969502; 9384377 [H]