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The map label for this gene is xdhC [H]

Identifier: 226948554

GI number: 226948554

Start: 1497860

End: 1498333

Strand: Direct

Name: xdhC [H]

Synonym: CLM_1446

Alternate gene names: 226948554

Gene position: 1497860-1498333 (Clockwise)

Preceding gene: 226948553

Following gene: 226948555

Centisome position: 36.05

GC content: 30.59

Gene sequence:

>474_bases
ATGAGTTTAAAAAGAAAAATAAAATTTACAGTTAATGATAAAAAGTATGAAGTAGAAATAGATATTAGAGAATCTTTATC
AGAAGTGTTAAGAAGTAGATTACATTTAACAGGTGTTAAACAAGGATGTCTTGTAGGAGAATGTGGAGCATGTACTGTCT
TAATAGATGGTGTCCCAACAGACTCATGTATTTACTTAGCGGCTTGGGCTGATGGTAAAACAATAAAAACTATTGAGGGG
GTACAAAAAAATGGTGAGCTTTCAGAGATTCAAAAAGCCTTTATAGATGAAGGTGCTGTACAATGTGGATTCTGTACACC
GGGTTTAGTTTTAACTACAACAGCTTTAGTAGAAAGCGAAAAAAACTATACTGATGATGAAATAAAAAGAGAAATATCAG
GTCATTTATGCAGATGTACTGGATATAATAAAATATTTAATGCTACCAAAAAAGCTATTTTAAAAAGAAAATAA

Upstream 100 bases:

>100_bases
CAAGAATTAACTTATAGAGGACTTAAAGAATCTGTTAAAAGAGCAGAAAATTTTGAAAATATAAAGTAATAGGATACAGT
TAGGGGGATGATGAATATAT

Downstream 100 bases:

>100_bases
TATTTAGGTTTATAATATGATAATCACTACAAGGTAAGTTTTGACAAGATTATTTTTAAAGTATAATATTAAGATATATA
GTTTAATTATTAAATGATTT

Product: xanthine dehydrogenase family protein iron-sulfur binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEIQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Sequences:

>Translated_157_residues
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEG
VQKNGELSEIQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
>Mature_156_residues
SLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPTDSCIYLAAWADGKTIKTIEGV
QKNGELSEIQKAFIDEGAVQCGFCTPGLVLTTTALVESEKNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK

Specific function: Iron-sulfur subunit of the xanthine dehydrogenase complex [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=162, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=32.484076433121, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1789232, Length=143, Percent_Identity=54.5454545454545, Blast_Score=161, Evalue=2e-41,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=37.037037037037, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=38.8157894736842, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=38.3116883116883, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32566215, Length=153, Percent_Identity=34.640522875817, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737937, Length=154, Percent_Identity=34.4155844155844, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=35, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=35, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24647201, Length=152, Percent_Identity=36.1842105263158, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=36.1290322580645, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=30.379746835443, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: NA

Molecular weight: Translated: 17363; Mature: 17232

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEIQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLKRKIKFTVNDKKYEVEIDIRESLSEVLRSRLHLTGVKQGCLVGECGACTVLIDGVPT
CCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEECCCC
DSCIYLAAWADGKTIKTIEGVQKNGELSEIQKAFIDEGAVQCGFCTPGLVLTTTALVESE
CCEEEEEEECCCCEEHHHHCCCCCCCHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCC
KNYTDDEIKREISGHLCRCTGYNKIFNATKKAILKRK
CCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]