Click here to switch to the map view.

The map label for this gene is xdhB [H]

Identifier: 226948553

GI number: 226948553

Start: 1496944

End: 1497828

Strand: Direct

Name: xdhB [H]

Synonym: CLM_1445

Alternate gene names: 226948553

Gene position: 1496944-1497828 (Clockwise)

Preceding gene: 226948552

Following gene: 226948554

Centisome position: 36.03

GC content: 28.25

Gene sequence:

>885_bases
ATGTATGATATAAATGAAATTTTAGAACCTAAAACATTAGAAAAGGCATTAGAATTATTATCAGAACACGATAATTTAAC
GGTAATAGCTGGAGGAACTGATGTACTTGTAAAACTTCATGAAGAAAGATTTAATTCTTTAAATTTAATAAGTATTAGAA
ACATAGAGAGTTTAAATGAAATAAAAGTAATTGAGAATGGCTCAATAGAAATAGGTGCTATGGCAACTTTTTCAGAAATA
TTTAGGGATGATATAGTGAATAAAAATATTCCTATACTAGCAGAAGCAGCAGTTTCTATGGGAGGACCTCAAATTAGAAA
TATGGCAACTATTGGAGGAAATATTTGTAATGGAGCTGTATCCGGAGATAGTGCACCATCATTATTTGCATTAAATAGTA
AATTAAGACTTAAATCTAAAAATGGTGAGAGAATAGTTAAAATAAAAGATTTTTATATAGGGCCTGGACAGGTTGACATC
AGGAAAGATGAGATATTAATTAGTATAATTATTGAAAAAAAAGATTATGAAAATAAGTATGGTAATTATATTAAATTTGC
TAGTAGAAATGCAATGGACATAGCTTTAATGGGAGTTGCTGTACTTGTAGAAGTTAAGAATAAAAAGTTTGAAGATTTAA
GAATAGCGTTAGGTGTATCAGGTCCAACACCTATAAGATGTGAAATAGCTGAAGCAGAGGGAAAGCATATGAAAGTTACG
GATGAAAATATAAGATTAATAGGAAATTTAGCTCTAAAATCTTCAAAAGCAATAGATTTTTGGAATGCATCAAAGGAATT
TAAAGAGCATTTAATACAAGAATTAACTTATAGAGGACTTAAAGAATCTGTTAAAAGAGCAGAAAATTTTGAAAATATAA
AGTAA

Upstream 100 bases:

>100_bases
TTAAATGCAACAGGAGTAGCATTTAATAAATTGCCAATGGATGCTCAATCTGTTTTTGAGAAATTTAAAGAGGTTGGACT
TATATAGGAGGCGAAATAAT

Downstream 100 bases:

>100_bases
TAGGATACAGTTAGGGGGATGATGAATATATATGAGTTTAAAAAGAAAAATAAAATTTACAGTTAATGATAAAAAGTATG
AAGTAGAAATAGATATTAGA

Product: xanthine dehydrogenase subunit XdhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVDI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLKESVKRAENFENIK

Sequences:

>Translated_294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVDI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLKESVKRAENFENIK
>Mature_294_residues
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNEIKVIENGSIEIGAMATFSEI
FRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAVSGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVDI
RKDEILISIIIEKKDYENKYGNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLKESVKRAENFENIK

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=287, Percent_Identity=38.6759581881533, Blast_Score=231, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17540638, Length=228, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737937, Length=234, Percent_Identity=29.4871794871795, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 32747; Mature: 32747

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNE
CCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHCCCEEEEEECCCCCCCE
IKVIENGSIEIGAMATFSEIFRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAV
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHCCCCCCCCCCC
SGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVDIRKDEILISIIIEKKDYENKY
CCCCCCCEEEECCEEEEECCCCCEEEEEEEEEECCCEEEEECCEEEEEEEEECCCCCCCC
GNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
CCEEEECCCCCHHHHHHHEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEE
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLKESVKRAENFENIK
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYDINEILEPKTLEKALELLSEHDNLTVIAGGTDVLVKLHEERFNSLNLISIRNIESLNE
CCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEHHHCCCEEEEEECCCCCCCE
IKVIENGSIEIGAMATFSEIFRDDIVNKNIPILAEAAVSMGGPQIRNMATIGGNICNGAV
EEEEECCCEEEEHHHHHHHHHHHHHCCCCCCEEEHHHHHCCCHHHHHHHCCCCCCCCCCC
SGDSAPSLFALNSKLRLKSKNGERIVKIKDFYIGPGQVDIRKDEILISIIIEKKDYENKY
CCCCCCCEEEECCEEEEECCCCCEEEEEEEEEECCCEEEEECCEEEEEEEEECCCCCCCC
GNYIKFASRNAMDIALMGVAVLVEVKNKKFEDLRIALGVSGPTPIRCEIAEAEGKHMKVT
CCEEEECCCCCHHHHHHHEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEE
DENIRLIGNLALKSSKAIDFWNASKEFKEHLIQELTYRGLKESVKRAENFENIK
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]