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The map label for this gene is agrA [H]

Identifier: 226948454

GI number: 226948454

Start: 1397419

End: 1398138

Strand: Direct

Name: agrA [H]

Synonym: CLM_1338

Alternate gene names: 226948454

Gene position: 1397419-1398138 (Clockwise)

Preceding gene: 226948452

Following gene: 226948455

Centisome position: 33.63

GC content: 26.81

Gene sequence:

>720_bases
ATGTTAAGAGTAATGATTTGTGAGGATAATGAAGTCCATAGAGTTAAGCTGAAGCAAATTGTAGAGAATACTATCCTAAG
AGAAAAATTAGATTTAGATATAGTACTAGCTACAGAAAATCCTGAGGAAATAATAAGTTATATAAAAGAAAACAGGAGCA
CTGGTATTTATCTTTTGGATGTGGAGCTAAAAAATGATATAAATGGTATAAAGCTTGGCGAAAAAATTAGAGAATTAGAT
CCATTAGGATATATAATATTTACTACTACTCATTTAGAAATGAGTTATTTAGCATTTAAATATAAAGTAGAAGCTATGGA
TTATGTAATTAAGGATGATGATGATTTTAAAGAAAGAGTAAATAGTTGTATTATAAAGGCTTATAATAGATATAATAAAC
AAGAACATGAAGAAGAATATATTTCAATAGATACAGATACACGAATAATAAATATTAGACCCAGTGACATTCTATTCATT
GAAACTACAGGAACCCCTCATAAAATAAGAATTCATGAGGAAACAAGACAGATTGAAATGTATGCTAATTTGAGAGATAT
ACAAAAAAAACTACCTCTAAGCTTTTATAGGTGCCATAAATCTTACATTGTAAACAAAAATAAAATTGAAGAAATAGACA
AGAAACATAATAAGATAATAATGAAAAATCAGGAAGAGTGTTATGTTTCCTTTAGATATATGAAGGGACTAATAGTATGA

Upstream 100 bases:

>100_bases
AAAGAAAACATTATCTTTCATGGGAAAAAATGTTGTTAGTATTTTTCATGTTTATATATGAATATCAAAAAGTTTTATAT
AAAAGTAAGGAGAAAAAGTA

Downstream 100 bases:

>100_bases
CTTTTACTAATTTTATAAATATGTTTTTACATTATACAATTATTCCCTCTATACTAATGAGTATTTTGTGCTTCATTTCA
ATATATATTTTATATAAAAA

Product: LytTr family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLRVMICEDNEVHRVKLKQIVENTILREKLDLDIVLATENPEEIISYIKENRSTGIYLLDVELKNDINGIKLGEKIRELD
PLGYIIFTTTHLEMSYLAFKYKVEAMDYVIKDDDDFKERVNSCIIKAYNRYNKQEHEEEYISIDTDTRIINIRPSDILFI
ETTGTPHKIRIHEETRQIEMYANLRDIQKKLPLSFYRCHKSYIVNKNKIEEIDKKHNKIIMKNQEECYVSFRYMKGLIV

Sequences:

>Translated_239_residues
MLRVMICEDNEVHRVKLKQIVENTILREKLDLDIVLATENPEEIISYIKENRSTGIYLLDVELKNDINGIKLGEKIRELD
PLGYIIFTTTHLEMSYLAFKYKVEAMDYVIKDDDDFKERVNSCIIKAYNRYNKQEHEEEYISIDTDTRIINIRPSDILFI
ETTGTPHKIRIHEETRQIEMYANLRDIQKKLPLSFYRCHKSYIVNKNKIEEIDKKHNKIIMKNQEECYVSFRYMKGLIV
>Mature_239_residues
MLRVMICEDNEVHRVKLKQIVENTILREKLDLDIVLATENPEEIISYIKENRSTGIYLLDVELKNDINGIKLGEKIRELD
PLGYIIFTTTHLEMSYLAFKYKVEAMDYVIKDDDDFKERVNSCIIKAYNRYNKQEHEEEYISIDTDTRIINIRPSDILFI
ETTGTPHKIRIHEETRQIEMYANLRDIQKKLPLSFYRCHKSYIVNKNKIEEIDKKHNKIIMKNQEECYVSFRYMKGLIV

Specific function: Required for high-level post-exponential phase expression of a series of secreted proteins [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082052, Length=250, Percent_Identity=26.4, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28544; Mature: 28544

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRVMICEDNEVHRVKLKQIVENTILREKLDLDIVLATENPEEIISYIKENRSTGIYLLD
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCCCEEEEE
VELKNDINGIKLGEKIRELDPLGYIIFTTTHLEMSYLAFKYKVEAMDYVIKDDDDFKERV
EEECCCCCCCHHHHHHHHCCCCEEEEEEEEEEEEEEEEEEEEEEEEEEEECCCHHHHHHH
NSCIIKAYNRYNKQEHEEEYISIDTDTRIINIRPSDILFIETTGTPHKIRIHEETRQIEM
HHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCEEEEEECCCCEEEEEECHHHEEHH
YANLRDIQKKLPLSFYRCHKSYIVNKNKIEEIDKKHNKIIMKNQEECYVSFRYMKGLIV
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCHHHEEEEEHHCCCCC
>Mature Secondary Structure
MLRVMICEDNEVHRVKLKQIVENTILREKLDLDIVLATENPEEIISYIKENRSTGIYLLD
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHCCCCCCEEEEE
VELKNDINGIKLGEKIRELDPLGYIIFTTTHLEMSYLAFKYKVEAMDYVIKDDDDFKERV
EEECCCCCCCHHHHHHHHCCCCEEEEEEEEEEEEEEEEEEEEEEEEEEEECCCHHHHHHH
NSCIIKAYNRYNKQEHEEEYISIDTDTRIINIRPSDILFIETTGTPHKIRIHEETRQIEM
HHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCEEEEEECCCCEEEEEECHHHEEHH
YANLRDIQKKLPLSFYRCHKSYIVNKNKIEEIDKKHNKIIMKNQEECYVSFRYMKGLIV
HHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHCCEEEEECCHHHEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA